Objective
Enzymes find manifold economical applications reflected by a rapidly growing multi-billion dollar market covering industrial sectors from textiles and detergents to pharmaceuticals and the food and feed market. In order to adapt nature's products to industrial processes, one of the challenging tasks of protein engineering is the development of enzymes with new or improved properties. In this context proteases are of outstanding interest.
Proteases are nowadays used as one of the main components of detergents and additionally have an enormous potential as highly target-specific pharmaceuticals. With their enzymatic turnover they can catalytically inactivate target proteins thereby acting efficiently in unrivalled low concentrations. c-LEcta has developed proprietary technologies to evolutionary develop and optimize properties of enzymes.
With its unrivalled screening technology allowing looking through enzyme libraries with complexities of up to 100 million variants, c-LEcta develops enzyme products to be used as biocatalysts in chemical synthesis and as tools in molecular biology research. The screening technology of c-LEcta will be adapted to the enzyme class of proteases allowing c-LEcta to address the above mentioned markets. c-LEcta will enter the enzyme engineering market for the development of improved proteases for the detergent market and will establish the requirements to address the challenge of evolving highly sequence specific proteases as pharmaceutical drug candidates.
Two experienced researcher from the protease field will be integrated into c-LEcta's lab staff for 2.5 years with the aim of establishing the adaptation of the technology and realizing the proof of principle for the technology application for at least two examples. These researchers will work closely together with the members of the c-LEcta staff, of which one will do training for three months in our partner organisation in Barcelona.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs
- natural sciences biological sciences genetics DNA
- natural sciences chemical sciences catalysis biocatalysis
- natural sciences biological sciences biochemistry biomolecules proteins enzymes
- natural sciences biological sciences molecular biology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-MOBILITY-3
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
LEIPZIG
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.