Objective
"Recent disparate studies on lion (Panthera leo) phylogeography have focused on both the mitochondrial cytochrome b gene and autosomal markers (SNP/Microsatellites) to produce a patchwork of results covering select regions of the lions range. The lack of an integrated approach to the question of lion evolutionary development has actively hindered conservation efforts, which rely on knowledge of the interrelationships between populations to effectively manage natural diversity. A major hurdle to achieving complete genetic coverage of lion populations throughout their modern range has been the very recent extinction of populations from North Africa (extinct ~1940) and the Middle East (extinct ~1957) and the rarity of lions representing the West African (P.l.senegalensis) and Central African (P.l.azandica) subspecies in the wild and in zoo populations. Recent advances in ancient DNA techniques now allow for the routine generation of sequence data in the range of millions of basepairs (MBP) from ancient material, opening up the possibility of recovering whole genomes (both mitochondrial and nuclear) from preserved remains. Application of cutting-edge aDNA techniques to the problems presented by lion phylogeography offers the means to produce a comprehensive study of lion evolution and expansion. To achieve these objective, the project will aim to:
1) Extract and enrich DNA from museum and modern P.leo samples representing rare and extinct populations, to produce high quality genomic libraries.
2) Generate complete mitochondrial genomes, the first to be sequenced from P.leo and informative autosomal genes as well as a library of modern P.leo LINE elements
3) Generate a species level phylogeny covering complete range for modern lions using combined dataset of mtDNA and nuDNA, incorporating all previously published data.
4) Identify Barbary lion specific mtDNA SNPs, nuDNA SNPs and LINEs with which to screen zoo population."
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences biological morphology comparative morphology
- natural sciences biological sciences genetics DNA
- natural sciences biological sciences genetics genomes
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2011-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
1165 KOBENHAVN
Denmark
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.