Objective The purpose of the project INSERT is to provide clinically relevant stratification and improved personalized radio-chemo therapy for brain tumour patients using a specifically developed multi-modality imaging tool. The system will also be used for early assessment of treatment efficacy. The initial focus will be on patients with glioma but there is future potential to target a range of tumours in the head and neck region. The proposed system is based on the development of a novel SPECT (Single Photon Emission Computed Tomography) system, suitable for insertion in the bore of an existing MRI (Magnetic Resonance Imaging) system, a cost-effective solution for widespread application. The combined system will allow the simultaneous measurement of anatomical (MRI) and functional (SPECT & MRI) information and the evaluation of their correlation in space and time. The SPECT design will enable acquisition of fast dynamic studies, with possibility for simultaneous measurement using multiple radionuclides (emitting at different energies), a distinct advantage compared to positron emission tomography (PET). This property can allow in-vivo simultaneous visualisation of spectrally resolved molecular and biochemical tumour properties. The stationary SPECT system is based on recently developed innovative gamma-ray detectors made with Silicon Drift Photodetectors, technology that achieves high-spatial resolution and is compatible with MRI thanks to the use of a silicon photodetector instead of photomultiplier tubes. The multi-modality SPECT/MRI imaging here proposed will apply a fully translational, vertical integration of research and development from technology design through preclinical models to clinical validation. Fields of science engineering and technologyelectrical engineering, electronic engineering, information engineeringelectronic engineeringsensorsoptical sensorsengineering and technologymedical engineeringdiagnostic imagingmagnetic resonance imagingnatural scienceschemical sciencesinorganic chemistrymetalloidsnatural scienceschemical sciencesnuclear chemistryradiation chemistrynatural sciencesphysical sciencestheoretical physicsparticle physicsphotons Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH.2012.1.2-1 - Development of technologies with a view to patient group stratification for personalised medicine applications Call for proposal FP7-HEALTH-2012-INNOVATION-1 See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator POLITECNICO DI MILANO Address Piazza leonardo da vinci 32 20133 Milano Italy See on map Region Nord-Ovest Lombardia Milano Activity type Higher or Secondary Education Establishments Administrative Contact Fabio Conti (Mr.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution € 715 000,00 Participants (10) Sort alphabetically Sort by EU Contribution Expand all Collapse all Mediso Orvosi Berendezes Fejleszto es Szerviz Kft. Hungary EU contribution € 1 100 000,00 Address Alsotorokvesz 14 1022 Budapest See on map Region Közép-Magyarország Budapest Budapest Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Erzsébet Zelei (Ms.) Links Contact the organisation Opens in new window Website Opens in new window FONDAZIONE BRUNO KESSLER Italy EU contribution € 400 000,00 Address Via santa croce 77 38122 Trento See on map Region Nord-Est Provincia Autonoma di Trento Trento Activity type Research Organisations Administrative Contact Umberto Silvestri (Mr.) Links Contact the organisation Opens in new window Website Opens in new window NUCLEARFIELDS INTERNATIONAL BV Netherlands EU contribution € 200 000,00 Address Akkervoortweg 7-11 5827AP Vortum mullem See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Gerjan Roelofs (Mr.) Links Contact the organisation Opens in new window Website Opens in new window MRI. TOOLS GMBH Germany EU contribution € 500 000,00 Address Robert rossle strasse 10 13125 Berlin See on map Region Berlin Berlin Berlin Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Thoralf Niendorf (Prof.) Links Contact the organisation Opens in new window Website Opens in new window UCL Elizabeth Garrett Anderson Institute for Women’s Health United Kingdom EU contribution € 575 622,70 Address Gower street WC1E 6BT London See on map Region London Inner London — West Camden and City of London Activity type Higher or Secondary Education Establishments Administrative Contact Greta Borg-Carbott (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITA VITA-SALUTE SAN RAFFAELE Italy EU contribution € 250 000,00 Address Via olgettina 58 20132 Milano See on map Region Nord-Ovest Lombardia Milano Activity type Higher or Secondary Education Establishments Administrative Contact Maria Rosa Pedrazzi (Dr.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITA DEGLI STUDI DI MILANO Italy EU contribution € 270 000,00 Address Via festa del perdono 7 20122 Milano See on map Region Nord-Ovest Lombardia Milano Activity type Higher or Secondary Education Establishments Administrative Contact Maria Antonia Giofrè (Dr.) Links Contact the organisation Opens in new window Website Opens in new window CROMED KUTATO ES SZOLGALTATO KOZPONTOK KFT Hungary EU contribution € 350 000,00 Address Baross utca 91 95 1047 Budapest See on map Region Közép-Magyarország Budapest Budapest Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Péter Riczu (Mr.) Links Contact the organisation Opens in new window Website Opens in new window CF CONSULTING FINANZIAMENTI UNIONE EUROPEA SRL Italy EU contribution € 115 000,00 Address Via giuseppe mussi 1 20154 Milano See on map Region Nord-Ovest Lombardia Milano Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Carla Finocchiaro (Ms.) Links Contact the organisation Opens in new window Website Opens in new window UNIVERSITY COLLEGE LONDON HOSPITALSNHS FOUNDATION TRUST United Kingdom EU contribution € 124 377,30 Address Euston road 250 NW1 2PG London See on map Region London Inner London — West Camden and City of London Activity type Research Organisations Administrative Contact Joe Mwanza (Mr.) Links Contact the organisation Opens in new window
