Heart OMics in AGEing

Project Information

HOMAGE

Grant agreement ID: 305507

Project closed

Start date 1 February 2013

End date 31 January 2019

Funded under

• Specific Programme "Cooperation": Health

Total cost € 16 366 890,17

EU contribution € 12 000 000,00

Coordinated by

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France

Objective

As more people survive into old age, the prevalence of heart failure (HF), one of the most common and debilitating diseases in older people, will rise still further. Delaying or preventing HF will have great benefit to those at personal risk, their families, society and the economy. HOMAGE aims to provide a biomarker (BM) approach that will a) help identify i. patients at high risk of developing HF before the onset of symptoms and ii. subsets of patients who are more likely to respond to specifically targeted therapies (personalized medicine). In available cohorts, we will identify the most promising ‘omics-based BM profiles for the pre-symptomatic diagnosis and future prediction of HF in patients at risk. The predictive value of the BMs for other co-morbidities commonly associated with HF and ageing will also be investigated. Furthermore, in a prospective trial, we will investigate the potential for targeting preventive therapy at patients with the greatest likelihood of response and the lowest risk of adverse effects. Our selection of innovative ‘omics-based BMs is based on knowledge of biological pathways of the disease, which may facilitate identification of ‘Biotargets’ for future therapies. On the economic side, HOMAGE will act as an economic catalyst for European SMEs in the field of cardiovascular and ageing BMs, estimated to peak annual turnovers of up to 800 M€.

Fields of science

• natural sciences › chemical sciences › catalysis
• medical and health sciences › clinical medicine › cardiology

Programme(s)

• FP7-HEALTH - Specific Programme "Cooperation": Health

Topic(s)

• HEALTH.2012.2.1.1-2 - Validation of -omics-based biomarkers for diseases affecting the elderly

Call for proposal

FP7-HEALTH-2012-INNOVATION-1
See other projects for this call

Funding Scheme

CP-IP - Large-scale integrating project

Coordinator

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE

• EU contribution: € 2 288 623,66
• Address: RUE DE TOLBIAC 101 ; 75654 Paris ; France
• Region: Ile-de-France › Ile-de-France › Paris
• Activity type: Research Organisations
• Administrative Contact: Marie-Ange Luc (Mrs.)
• Total cost: No data

Participants (21)

INSERM TRANSFERT SA

France

• EU contribution: € 450 000,00
• Address: 10 RUE D'ORADOUR-SUR-GLANE - PARISANTE CAMPUS ; 75015 PARIS
• Region: Ile-de-France › Ile-de-France › Paris
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Patricia Joseph-Mathieu (Ms.)
• Total cost: No data

FONDATION TRANSPLANTATION

France

• EU contribution: € 827 185,89
• Address: rue de la Brot 4 ; 21850 St Apollinaire
• Activity type: Research Organisations
• Administrative Contact: Stéphanie Grojean (Dr.)
• Total cost: No data

ACS BIOMARKER BV

Netherlands

• EU contribution: € 1 762 123,92
• Address: MEIBERGDREEF 5 ; 1105 AZ AMSTERDAM
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Heico Breek (Mr.)
• Total cost: No data

Randox Clinics Limited

Participation ended

United Kingdom

• EU contribution: € 43 655,52
• Address: Diamond Road 34 ; BT29 4QY Crumlin
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Andrew Cartwright (Mr.)
• Total cost: No data

MEDIZINISCHE UNIVERSITAT GRAZ

Participation ended

Austria

• EU contribution: € 19 574,47
• Address: NEUE STIFTINGTALSTRASSE 6 ; 8010 Graz
• Region: Südösterreich › Steiermark › Graz
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Burkert Pieske (Prof.)
• Total cost: No data

THE UNIVERSITY OF MANCHESTER

Participation ended

United Kingdom

• EU contribution: No data
• Address: OXFORD ROAD ; M13 9PL Manchester
• Region: North West (England) › Greater Manchester › Manchester
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Liz Fay (Ms.)
• Total cost: No data

FUNDACION PARA LA INVESTIGACION MEDICA APLICADA FIMA

Spain

• EU contribution: € 310 045,05
• Address: AVENIDA DE PIO XII 55 ; 31008 Pamplona
• Region: Noreste › Comunidad Foral de Navarra › Navarra
• Activity type: Research Organisations
• Administrative Contact: Andrew Solomon (Dr.)
• Total cost: No data

UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN

Ireland

• EU contribution: € 341 742,53
• Address: BELFIELD ; 4 Dublin
• Region: Ireland › Eastern and Midland › Dublin
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Donal Doolan (Mr.)
• Total cost: No data

UNIVERSITY OF HULL

United Kingdom

• EU contribution: € 575 893,07
• Address: COTTINGHAM ROAD ; HU6 7RX Hull
• Region: Yorkshire and the Humber › East Yorkshire and Northern Lincolnshire › Kingston upon Hull, City of
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Neil Scott (Mr.)
• Total cost: No data

UNIVERSITEIT MAASTRICHT

Netherlands

• EU contribution: € 1 000 658,31
• Address: MINDERBROEDERSBERG 4 ; 6200 MD Maastricht
• Region: Zuid-Nederland › Limburg (NL) › Zuid-Limburg
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Rob Van Der Zander (Mr.)
• Total cost: No data

ISTITUTO DI RICERCHE FARMACOLOGICHE MARIO NEGRI

Italy

• EU contribution: € 381 362,14
• Address: VIA MARIO NEGRI 2 ; 20156 Milano
• Region: Nord-Ovest › Lombardia › Milano
• Activity type: Research Organisations
• Administrative Contact: Maria Grazia Pezzoni (Ms.)
• Total cost: No data

MEDIZINISCHE HOCHSCHULE HANNOVER

Germany

• EU contribution: € 382 605,19
• Address: Carl-Neuberg-Strasse 1 ; 30625 Hannover
• Region: Niedersachsen › Hannover › Region Hannover
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Frank Dittrich (Mr.)
• Total cost: No data

KATHOLIEKE UNIVERSITEIT LEUVEN

Belgium

• EU contribution: € 872 879,91
• Address: OUDE MARKT 13 ; 3000 Leuven
• Region: Vlaams Gewest › Prov. Vlaams-Brabant › Arr. Leuven
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Elke Lammertyn (Dr.)
• Total cost: No data

LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE ROYAL CHARTER

United Kingdom

• EU contribution: € 190 101,50
• Address: KEPPEL STREET ; WC1E 7HT London
• Region: London › Inner London — West › Camden and City of London
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Michael Robinson (Mr.)
• Total cost: No data

EMORY UNIVERSITY NON PROFIT CORP

Participation ended

United States

• EU contribution: € 40 566,49
• Address: Clifton Road, NE, 4th Floor 1599 ; 30322 Atlanta
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Javed Butler (Prof.)
• Total cost: No data

UNIVERSITY OF GLASGOW

United Kingdom

• EU contribution: € 288 183,03
• Address: UNIVERSITY AVENUE ; G12 8QQ Glasgow
• Region: Scotland › West Central Scotland › Glasgow City
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Joe Galloway (Mr.)
• Total cost: No data

MOSAIQUES DIAGNOSTICS GMBH

Germany

• EU contribution: € 863 635,47
• Address: ROTENBURGER STRASSE 20 ; 30659 Hannover
• Region: Niedersachsen › Hannover › Region Hannover
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Harald Mischak (Prof.)
• Total cost: No data

THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK

Participation ended

United States

• EU contribution: € 64 203,47
• Address: STATE STREET 35 ; 12201 Albany Ny
• Activity type: Other
• Administrative Contact: Alina Stroia (Ms.)
• Total cost: No data

UNIVERSITY OF KEELE ROYAL CHARTER

United Kingdom

• EU contribution: € 190 438,36
• Address: KEELE UNIVERSITY FINANCE DPT ; ST5 5BG Keele
• Region: West Midlands (England) › Shropshire and Staffordshire › Staffordshire CC
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: James Allman (Mr.)
• Total cost: No data

TATAA BIOCENTER AB

Sweden

• EU contribution: € 930 600,72
• Address: SOFIEROGATAN 3A ; 412 51 GOTEBORG
• Region: Södra Sverige › Västsverige › Västra Götalands län
• Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
• Administrative Contact: Anne Hansen (Ms.)
• Total cost: No data

CHARITE - UNIVERSITAETSMEDIZIN BERLIN

Germany

• EU contribution: € 175 921,30
• Address: Chariteplatz 1 ; 10117 Berlin
• Region: Berlin › Berlin › Berlin
• Activity type: Higher or Secondary Education Establishments
• Administrative Contact: Martina Eickmann (Mrs.)
• Total cost: No data