Skip to main content

Optimisation of early reproductive success in dairy cattle through the definition of new traits and improved reproductive biotechnology

Objectif

Good fertility is essential for the sustainability of livestock production. Of all livestock sectors, fertility of dairy cattle is raising the greatest cause for concern. Cow fertility has declined, particularly in Holstein cattle, from 80% pregnancy to first service 20 years ago to less than 40% today. Poor fertility is one of the main reasons for early culling, such that modern dairy cows complete fewer than 3 lactations, on average. The FECUND project will address the metabolic and genetic causes of low reproductive success of dairy cows in an interdisciplinary approach that will integrate in vivo and in vitro studies, biology, physiology, -omics technologies and bioinformatics. FECUND will focus on the early phases of reproduction from oocyte development to implantation of the conceptus. Starting from biological materials produced from high and low genetic merit cattle and from cows under energy stress of early lactation vs dry cows and heifers, FECUND will study, independently, the effects of genetics and metabolic stress on reproductive physiology to identify factors and early markers associated with high and low developmental potential, and with positive mother-conceptus interaction during the early stages of reproduction. These data will be mined to reveal physiological pathways and key candidate genes controlling variations of fertility. The biological knowledge created on early reproductive events in vivo will be validated in vitro, and extended to create further knowledge on the effects of the local environment on oocyte and embryo programming at the epigenetic level. Validated information will be used to improve herd management, gene assisted and genomic selection and assisted reproductive technologies, from in vitro ooctye maturation to optimised embryo culture. Information on biomarkers, indicator traits and improvements in assisted reproduction will be translated to applications that can be immediately implemented by SMEs.

Appel à propositions

FP7-KBBE-2012-6-singlestage
Voir d’autres projets de cet appel

Coordinateur

Fondazione Parco Tecnologico Padano
Adresse
Via Einstein - Loc. Cascina Codazza
26900 Lodi
Italie

Voir sur la carte

Type d’activité
Research Organisations
Contact administratif
Augusto Prete (Mr.)
Contribution de l’UE
€ 746 552,20

Participants (12)

LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Allemagne
Contribution de l’UE
€ 301 932,50
Adresse
Geschwister Scholl Platz 1
80539 Muenchen

Voir sur la carte

Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Helmut Blum (Dr.)
INSTITUT NATIONAL DE RECHERCHE POUR L'AGRICULTURE, L'ALIMENTATION ET L'ENVIRONNEMENT
France
Contribution de l’UE
€ 264 750,80
Adresse
147 Rue De L'universite
75007 Paris Cedex 07

Voir sur la carte

Type d’activité
Research Organisations
Contact administratif
Claire Poitelon (Dr.)
UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN
Irlande
Contribution de l’UE
€ 485 200
Adresse
Belfield
4 Dublin

Voir sur la carte

Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Donal Doolan (Mr.)
VETERINAERMEDIZINISCHE UNIVERSITAET WIEN
Autriche
Contribution de l’UE
€ 248 280
Adresse
Veterinaerplatz 1
1210 Vienna

Voir sur la carte

Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Sabine Ecker (Dr.)
INSTYTUT GENETYKI I BIOTECHNOLOGII ZWIERZAT POLSKIEJ AKADEMII NAUK
Pologne
Contribution de l’UE
€ 210 000
Adresse
Jastrzebiec, Ul. Postepu 36a
05-552 Magdalenka

Voir sur la carte

Type d’activité
Research Organisations
Contact administratif
Cyprian Tomasik (Mr.)
AVANTEA srl
Italie
Contribution de l’UE
€ 285 000
Adresse
Via Cabrini 12
26100 Cremona

Voir sur la carte

Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Giovanna Lazzari (Dr.)
BAYERN GENETIK GMBH

Participation terminée

Allemagne
Adresse
Gut Altenbach
84036 Landshut

Voir sur la carte

Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Christoph Gschoederer (Mr.)
NATIONAL CATTLE BREEDING CENTRE LIMITED
Irlande
Contribution de l’UE
€ 20 040
Adresse
Kilcorney
Enfield

Voir sur la carte

Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Bernard Eivers (Mr.)
ELIANCE
France
Contribution de l’UE
€ 288 037,50
Adresse
149 Rue De Bercy
75595 Paris Cedex 12

Voir sur la carte

Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Claire Ponsart (Dr.)
OSRODEK HODOWLI ZARODOWEJ OSIECINYSP ZOO

Participation terminée

Pologne
Adresse
Ul Wloclawska 2
88 220 Osieciny

Voir sur la carte

Type d’activité
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Contact administratif
Jacek Wyrębski (Mr.)
EUROPEAN FORUM OF FARM ANIMAL BREEDERS
Pays-Bas
Contribution de l’UE
€ 49 600
Adresse
Silkeborg 75
2905 AT Capelle Aan Den Ijssel

Voir sur la carte

Type d’activité
Research Organisations
Contact administratif
Marjolein Neuteboom (Ms.)
UNIVERSITA CATTOLICA DEL SACRO CUORE
Italie
Contribution de l’UE
€ 100 000
Adresse
Largo Gemelli 1
20123 Milano

Voir sur la carte

Type d’activité
Higher or Secondary Education Establishments
Contact administratif
Mauro Balordi (Dr.)