Objective
Thiols (RSH) play an important role in the living cells taking part in the chemical repair reactions of radical damages induced in DNA. As the result of such repair thiyl radicals (RS) are formed. The aim of this project is to broaden the knowledge concer ning kinetics of chemical repair reactions of nucleobase derived radicals by thiols. Moreover, to study in detail photosensitized generation of thiyl radicals from thiols and their possible interaction with unsaturated bonds in purines. In continuation of the former RTN project, by means of pulse radiolysis behaviour of the nucleobase-derived radicals with defined structures in the presence of thiols will be investigated. On this basis the repair rate constants will be determined. Photosensitized generation of thiyl radicals will be studied by laser flash photolysis technique. Behaviour of thiyl radicals in the presence of purines will be observed in order to answer the question whether thiyl radicals interact with unsaturated bonds in purine bases.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences organic chemistry ketones
- natural sciences biological sciences genetics DNA
- natural sciences chemical sciences electrochemistry electrolysis
- natural sciences chemical sciences nuclear chemistry radiation chemistry
- natural sciences physical sciences optics laser physics
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2004-MOBILITY-11
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
POZNAN
Poland
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.