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Content archived on 2024-06-18

Methodology for and Synthesis of Highly Congested Molecules

Objective

The development of new methodologies which allow for the direct synthesis of highly complex molecular entities bearing vicinal all carbon quaternary stereocentres remains a most important goal for modern synthetic chemists.
The aim of this proposal is to develop cutting-edge methodology for congested molecule synthesis and apply it to the total synthesis of the core of a highly complex natural product.
Phase 1 of the project will involve the development of three related methodologies which will allow for the efficient synthesis of a wide range of highly complex tricyclic molecules bearing multiple stereocentres including vicinal all carbon quaternary stereocentres from simple achiral starting materials.
In Phase 2 of the project the developed methodologies will be used to synthesise the complex tetracyclic core of a highly complex biologically active terpenoid natural product. The tetracyclic core will be further functionalised using state-of-the-art synthetic transformations.

Topic(s)

Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.

Call for proposal

Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.

FP7-PEOPLE-2012-IEF
See other projects for this call

Funding Scheme

Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.

MC-IEF - Intra-European Fellowships (IEF)

Coordinator

THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
EU contribution
€ 221 606,40
Address
WELLINGTON SQUARE UNIVERSITY OFFICES
OX1 2JD Oxford
United Kingdom

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Region
South East (England) Berkshire, Buckinghamshire and Oxfordshire Oxfordshire
Activity type
Higher or Secondary Education Establishments
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Total cost

The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.

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