Objective
                                The development of new methodologies which allow for the direct synthesis of highly complex molecular entities bearing vicinal all carbon quaternary stereocentres remains a most important goal for modern synthetic chemists.
The aim of this proposal is to develop cutting-edge methodology for congested molecule synthesis and apply it to the total synthesis of the core of a highly complex natural product.
Phase 1 of the project will involve the development of three related methodologies which will allow for the efficient synthesis of a wide range of highly complex tricyclic molecules bearing multiple stereocentres including vicinal all carbon quaternary stereocentres from simple achiral starting materials.
In Phase 2 of the project the developed methodologies will be used to synthesise the complex tetracyclic core of a highly complex biologically active terpenoid natural product.  The tetracyclic core will be further functionalised using state-of-the-art synthetic transformations.
                            
    Programme(s)
    
      
      
        Multi-annual funding programmes that define the EU’s priorities for research and innovation.
        
      
    
  
      
  Multi-annual funding programmes that define the EU’s priorities for research and innovation.
    Topic(s)
    
      
      
        Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
        
      
    
  
      
  Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
      Call for proposal
      
        
        
          Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
          
        
      
    
          Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
        FP7-PEOPLE-2012-IEF
          
            See other projects for this call
          
      
    Funding Scheme
    
      
      
        Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
        
      
    
  
  
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
OX1 2JD Oxford
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.