Objectif "Perception, cognition and behaviour are achieved through the coordination of multiple brain regions, which exchange information between each other. Large-scale functional interactions arise at two distinct but potentially related temporal scales: “slow” hemodynamic fluctuations measured with functional magnetic resonance imaging (fMRI); and “fast” electrophysiological oscillations of the neurons, as measured non-invasively by electroencephalography (EEG) and magnetoencephalography, and invasively at finer spatial scales by local field potentials and multi-unit activity. Despite enormous recent progress, our understanding of the relationship between, and functional role of fast and slow synchronization in inter-areal cortical communication is still limited. In this project, we will study interactions in large-scale functional networks of healthy human volunteers using combined electrophysiological and hemodynamic measures. We will characterize functional brain networks showing coherent hemodynamic activity at rest and examine how the functional architecture of these networks varies with active behaviour. Moreover, we will study large-scale interactions at different spatio-temporal scales, relating slow fMRI fluctuations with fast EEG oscillations recorded simultaneously. Finally, we will target specific areas under different states by transcranial magnetic stimulation to investigate the causal effects of these focal perturbations on the spatial and temporal properties of brain networks. These studies will provide deeper insights into the mechanisms underlying inter-areal cortical communication and their functional role with respect to behaviour." Champ scientifique engineering and technologymedical engineeringdiagnostic imagingmagnetic resonance imaging Programme(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Thème(s) FP7-PEOPLE-2012-CIG - Marie-Curie Action: "Career Integration Grants" Appel à propositions FP7-PEOPLE-2012-CIG Voir d’autres projets de cet appel Régime de financement MC-CIG - Support for training and career development of researcher (CIG) Coordinateur EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH Contribution de l’UE € 100 000,00 Adresse Raemistrasse 101 8092 Zuerich Suisse Voir sur la carte Région Schweiz/Suisse/Svizzera Zürich Zürich Type d’activité Higher or Secondary Education Establishments Contact administratif Nicole Wenderoth (Prof.) Liens Contacter l’organisation Opens in new window Site web Opens in new window Coût total Aucune donnée
