Objective
The OptiCryst STREP aims to take a leap forward scientifically and commercially to obtain high-quality crystals of proteins which are proving difficult to crystallise, providing a support platform for Europe's Structural Genomics initiatives that are struggling to deliver structures. Protein crystallisation has gained a new strategic and commercial relevance in the post-genomic era due to its pivotal role in Structural Genomics: producing high-quality crystals has always been a bottleneck to structure determination and this problem is becoming increasingly acute within worldwide initiatives.
This is especially true for challenging therapeutically important proteins that typically do not form suitable crystals. It is clear that the only way to relieve the bottleneck of crystallisation is to focus a concerted effort on the science that underlies it. Research advances in recent years have opened up the scope for development and commercialisation of new tools and methods to adopt this relatively unexplored approach. 7 research-intensive SMEs' from 5 European countries (holding 54.4% of the total budget) and 4 research institutions' scientific expertise will reinforce technological knowledge and the validation of innovative solutions. The SMEs play leading roles and one is the coordinator. Opticryst will capitalise on this momentum and prevent difficult proteins from being consigned to Structural Genomics's 'back burner'.
Opticryst has 2 key objectives: Develop and commercialise new, improved methods and equipment to obtain high-quality crystals of proteins difficult to crystallise; develop a platform for supporting the Structural Genomics initiatives in Europe struggling to deliver the number of structures that was hoped for. In conclusion, OptiCryst is designed to establish a new state-of-the-art in protein crystallisation. Our consortium of commercial and academic partners will give Europe a leading role in an area crucial to improving human health and the economy.'
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics
- natural sciences biological sciences biochemistry biomolecules proteins
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2005-LIFESCIHEALTH-7
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
BIRMINGHAM
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.