Objective
EMBIC virtual European laboratory on major mechanisms of implantation will study thoroughly the main cellular - cytokine networks/ key pathways promoting the de novo development of the decidua basalis and the mature placenta. Present fragmentation of experimental capacity and disparate approaches result in lack of a comprehensive skills base, and of access to specialised approaches/ technological platforms such as strict animal experimentation, genomics and proteomics facilities or multicentric clinical evaluation. Which need coordinated approach. We will thus: 1. Assemble critical talents and approaches, to Integrate EMBIC laboratories via the joint programme of activities: 1.1. Early embryo signalling to ultimately allow selection of only those embryos which will effectively implant; 1.2. Key events in tissue remodelling: 1.3. Homing/ proper activation of Natural Killer (NK) cells 1.4. Role of MHC class I gene products and their recognition by NK cells 1.5. Control of the inflammation complement related pathways 1.6. Cytokine/ chemokines/ profiling 1.7. Invasion and early post implantation events, Matrix Metallo Protease based proteolysis/ adhesion molecule functions. 2. Constitute a European cohort of infertile women and RT generated DNA, sera and micro-biopsy tissue samples banks. 3. Establish guidelines for management of infertile women combined with diagnosis procedures and ultimately recombinant technologies therapies for selected pathologies. 4. Open the network for education and cooperative experimentation. EMBIC will contribute and benefit from the creation of integrated platforms based on animal models, genomic and proteomic facilities, protein intra-net database set-up, integrated clinical set-up, and will spread excellence by facilitating the exchange of scientists within the laboratories, promote recruitment/training of out network post-docs, organise workshops and satellite meetings and an annual summer school.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine gynaecology reproductive medicine
- medical and health sciences basic medicine immunology
- medical and health sciences clinical medicine obstetrics
- medical and health sciences basic medicine pathology
- medical and health sciences clinical medicine embryology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2003-LIFESCIHEALTH-I
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
PARIS
France
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Participants (22)
OXFORD
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BELLATERRA CERDANYOLA DEL VALLÈS)
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ROME
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RIJEKA
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TRIESTE
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MILAN
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BERLIN
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JENA
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PARIS
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LEICESTER
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FLORENCE
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LIÈGE
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PECS
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GRAZ
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PARIS
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PARIS
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SAINT QUENTIN EN YVELINES
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ROZZANO - MILANO
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DUBLIN 4
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ATHENS
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LIEGE
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EDINBURGH
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