Objective
Yeast mannoprotein could be useful to reduce colonisation by enteropathogenic bacteria. The use of yeast cells or yeast cell wall preparations has been associated with the reduction of different enteric pathogens. Campylobacter je/uni and related species a re now recognised as the most common causes of bacterial foodborne diarrhoeal disease throughout the world and poultry, especially chickens, are the main reservoir of this pathogen. However, no attempts have been made to establish a relationship between specific mannoproteins and its efficacy to reduce Campylobacter in chickens.
We propose as main aim of this investigation to study the effect of mannoproteins on Campylobacter adherence to ephitelial cells of chicken gut, identifying fractions especially effective against Campylobacter. Mannoprotein properties may be affected by the procedure used for its extraction and purification. Thus, different methods for mannoprotein extraction and fractionation will be evaluated. Also, some enological variables that ma y have influence on the mannoproteins obtained, as the different steps of winemaking, culture conditions and relevant enological stresses, will be studied.
Mannoproteins as inhibitor of Campylobacter adherence will be tested, trying to establish a relation ship between mannoproteins composition and its capacity to inhibit Campylobacter adherence in vitro. This information may contribute to establish novel industrial process for preparation of mannoproteins and may have a positive influence on the selection o f new natural strains and the genetic engineering experiments designed to obtain super producers strains of specific mannoproteins. Findings derived of this project will contribute to understand the relationship between mannoproteins composition and its potential effect on food security. These investigations may provide theoretical and practical valuable results useful for academic and food industry.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences microbiology bacteriology
- medical and health sciences medical biotechnology genetic engineering
- medical and health sciences health sciences nutrition
- natural sciences chemical sciences organic chemistry alcohols
- engineering and technology industrial biotechnology bioprocessing technologies fermentation
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-11
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
MADRID
Spain
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.