Objective The overall aim of this project is to identify genes associated with stress and disease resitance in oyster, trout, sea bream, and sea bass in order to provide a physiological and genetic basis for marker-assisted selection. These studies will be carried o ut for fish using stress and pathogen challenges directly relevant to aquaculture and for oyster using environmental conditions that are known to lead to significant summer mortalities. In Part 1 of the project the genes involved in the functional response to stress or pathogen exposure will be identified. This will be carried out in the four species by (i) constructing relevant EST collections using SSH cDNA libraries which will be spotted on microarrays, followed by (ii) analysis of gene expression profil es in various tissues of animals exposed to stressors or pathogens. This analysis will be also carried out in families that are divergent for stress response or disease resistance (fish) or for summer survival (oyster). In order to investigate relationship between potential candidate genes and QTL for these traits, Part 2 of the project will identify Single Nucleotide Polymorphisms (SNP) in these candidate genes in oyster and trout. This polymorphism will be analysed both in the EST sequences and in the pro moter region. In Part 3 of the project QTL analysis will be used to identify genes that are associated with stress specific traits and disease resistance traits using previously characterized SNP and also microsatellites markers. We will also carry out map ping of these genes in linkage and gene maps.Part 4 is devoted to outline operational genetic protocols incorporating identified QTL and traditional breeding approaches in oyster, sea bream and sea bass. This knowledge will be transferred to the industry t hrough organisation of workshops gathering scientists and RTD performers. Fields of science agricultural sciencesagricultural biotechnologymarker assisted selection Keywords disease resistance fish gene expression quantitative trait locus shellfish stress response Programme(s) FP6-POLICIES - Policy support: Specific activities covering wider field of research under the Focusing and Integrating Community Research programme 2002-2006. Topic(s) POLICIES-1.3 - The modernisation and sustainability of fisheries policies Call for proposal FP6-2003-SSP-3 See other projects for this call Funding Scheme NoE - Network of Excellence Coordinator INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE EU contribution No data Address 147 rue de l'universite PARIS France See on map Links Website Opens in new window Total cost No data Participants (16) Sort alphabetically Sort by EU Contribution Expand all Collapse all THE UNIVERSITY COURT OF THE UNIVERSITY OF ABERDEEN United Kingdom EU contribution No data Address Kings College AB24 3FX ABERDEEN See on map Links Website Opens in new window Total cost No data THE NATURAL ENVIRONMENT RESEARCH COUNCIL United Kingdom EU contribution No data Address Polaris House, North Star Avenue SWINDON See on map Links Website Opens in new window Total cost No data UPPSALA UNIVERSITY Sweden EU contribution No data Address S:t Olofsgatan 10B 256 UPPSALA See on map Links Website Opens in new window Total cost No data INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER France EU contribution No data Address Rue Jean-Jacques Rousseau, 155 ISSY-LES-MOULINEAUX See on map Links Website Opens in new window Total cost No data AGENCIA ESTATAL CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS Spain EU contribution No data Address Serrano 117 MADRID See on map Total cost No data INSTITUTO CANARIO DE CIENCIAS MARINAS Spain EU contribution No data Address muelle de Taliarte s/n TELDE See on map Links Website Opens in new window Total cost No data WAGENINGEN UNIVERSITY Netherlands EU contribution No data Address Costerweg 50 9101 WAGENINGEN See on map Links Website Opens in new window Total cost No data NATIONAL UNIVERSITY OF IRELAND, GALWAY Ireland EU contribution No data Address University Road - GALWAY See on map Links Website Opens in new window Total cost No data PLYMOUTH MARINE LABORATORY United Kingdom EU contribution No data Address Prospect Place, The Hoe PLYMOUTH See on map Links Website Opens in new window Total cost No data CENTRO DE CIENCIAS DO MAR DO ALGARVE Portugal EU contribution No data Address Universidade do Algarve, Campus de Gambelas FARO See on map Links Website Opens in new window Total cost No data KATHOLIEKE UNIVERSITEIT LEUVEN Belgium EU contribution No data Address Oude Markt 13 LEUVEN See on map Links Website Opens in new window Total cost No data HELLENIC CENTRE FOR MARINE RESEARCH Greece EU contribution No data Address 46.7 km Athens-Sounio, Mavro Lithari 712 ANAVISSOS ATTIKIS See on map Links Website Opens in new window Total cost No data UNIVERSITA DEGLI STUDI DI PADOVA Italy EU contribution No data Address Via 8 Febbraio, 2 PADOVA See on map Links Website Opens in new window Total cost No data ROSLIN FOUNDATION United Kingdom EU contribution No data Address Wallace Building, Roslin Biocentre ROSLIN (MIDLOTHIAN) See on map Links Website Opens in new window Total cost No data CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE DELEGATION REGION BRETAGNE ET PAYS DE LA LOIRE France EU contribution No data Address 74 E RUE DE PARIS RENNES See on map Links Website Opens in new window Total cost No data NIREUS CHIOS AQUACULTURE SA Greece EU contribution No data Address 1st klm KOROPIOU-VARIS KOROPI See on map Links Website Opens in new window Total cost No data
