Project description
Virtual Physiological Human
Developing robust, reproducible, interoperable and collaborative hyper-models of diseases and normal physiology is a sine qua non necessity if rational, coherent and comprehensive exploitation of the invaluable information hidden within human multiscale biological data is envisaged. Responding to this imperative in the context of both the broad Virtual Physiological Human (VPH) initiative and the paradigmatic cancer domain, CHIC proposes the development of a suite of tools, services and secure infrastructure that will support accessibility and reusability of VPH mathematical and computational hypermodels. These will include a hypermodelling infrastructure consisting primarily of a hypermodelling editor and a hypermodelling execution environment, an infrastructure for semantic metadata management, a hypermodel repository, a hypermodel-driven clinical data repository, a distributed metadata repository and an in silico trial repository for the storage of executed simulation scenarios. Multiscale models and data will be semantically annotated using the ontological and annotating tools to be developed. An image processing and visualization toolkit, and cloud and virtualization services will also be developed. The CHIC tools, services, infrastructure and repositories will provide the community with a collaborative interface for exchanging knowledge and sharing work in an effective and standardized way. A number of open source features and tools will enhance usability and accessibility. In order to ensure clinical relevance and foster clinical acceptance of hypermodelling in the future, the whole endeavour will be driven by the clinical partners of the consortium. Cancer hypermodels to be collaboratively developed by the consortium cancer modellers will provide the framework and the testbed for the development of the CHIC technologies. Clinical adaptation and partial clinical validation of hypermodels and hypermodel oncosimulators will be undertaken.
Fields of science
Call for proposal
FP7-ICT-2011-9
See other projects for this call
Funding Scheme
CP - Collaborative project (generic)Coordinator
106 82 ATHINA
Greece
See on map
Participants (16)
9830 Sint-Martens-Latem
See on map
3000 Leuven
See on map
3012 Bern
See on map
66123 Saarbrucken
See on map
30167 Hannover
See on map
66386 St Ingbert
See on map
710 04 IRAKLEIO
See on map
70013 Irakleio
See on map
40033 Casalecchio Di Reno Bo
See on map
10124 Torino
See on map
5656 AG Eindhoven
See on map
S10 2TN Sheffield
See on map
OX1 2JD Oxford
See on map
LU1 3JU Luton
See on map
WC1E 6BT LONDON
See on map
19104 Philadelphia
See on map