Objective
Traumatic Brain Injury (TBI) is a major cause of death and disability, leading to great personal suffering to victim and relatives, as well as huge direct and indirect costs to society. Strong ethical, medical, social and health economic reasons therefore exist for improving treatment. The CENTER-TBI project will collect a prospective, contemporary, highly granular, observational dataset of 5400 patients, which will be used for better characterization of TBI and for Comparative Effectiveness Research (CER). The generalisability of our results will be reinforced by a contemporaneous registry level data collection in 15-25,000 patients. Our conceptual approach is to exploit the heterogeneity in biology, care, and outcome of TBI, to discover novel pathophysiology, refine disease characterization, and identify effective clinical interventions. Key elements are the use of emerging technologies (biomarkers, genomics and advanced MR imaging) in large numbers of patients, across the entire course of TBI (from injury to late outcome) and across all severities of injury (mild to severe). Improved characterization with these tools will aid Precision Medicine, a concept recently advocated by the US National Academy of Science, facilitating targeted management for individual patients. Our consortium includes leading experts and will bring outstanding biostatistical and neuroinformatics expertise to the project. Collaborations with external partners, other FP7 consortia, and international links within InTBIR, will greatly augment scientific resources and broaden the global scope of our research. We anticipate that the project could revolutionize our view of TBI, leading to more effective and efficient therapy, thus improving outcome and reducing costs. These outcomes reflect the goals of CER to assist consumers, clinicians, health care purchasers, and policy makers to make informed decisions, and will improve healthcare at both individual and population levels.
Fields of science
Call for proposal
FP7-HEALTH-2013-INNOVATION-1
See other projects for this call
Funding Scheme
CP-IP - Large-scale integrating projectCoordinator
UNIVERSITAIR ZIEKENHUIS ANTWERPEN
EU contribution
€ 11 728 072,00
Address
DRIE EIKENSTRAAT 655
2650 Edegem
Belgium
2650 Edegem
Belgium
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Region
Vlaams Gewest
Prov. Antwerpen
Arr. Antwerpen
Activity type
Research Organisations
Administrative Contact
Tomas Menovsky (Prof.)
Links
Total cost
No data
Participants (42)
THE CHANCELLOR MASTERS AND SCHOLARS OF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
EU contribution
€ 2 997 529,00
Address
TRINITY LANE THE OLD SCHOOLS
CB2 1TN Cambridge
CB2 1TN Cambridge
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Region
East of England
East Anglia
Cambridgeshire CC
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Renata Schaeffer (Ms.)
Links
Total cost
No data
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 1 049 970,00
Address
Nobels Vag 5
17177 Stockholm
17177 Stockholm
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Region
Östra Sverige
Stockholm
Stockholms län
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Karin Buzzi-Donato (Ms.)
Links
Total cost
No data
ERASMUS UNIVERSITAIR MEDISCH CENTRUM ROTTERDAM
Netherlands
EU contribution
€ 3 054 520,00
Address
DR MOLEWATERPLEIN 40
3015 GD Rotterdam
3015 GD Rotterdam
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Region
West-Nederland
Zuid-Holland
Groot-Rijnmond
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Hester Lingsma (Dr.)
Links
Total cost
No data
UNIVERSITAETSMEDIZIN GOETTINGEN - GEORG-AUGUST-UNIVERSITAET GOETTINGEN - STIFTUNG OEFFENTLICHEN RECHTS
Germany
EU contribution
€ 866 664,00
Address
Robert-Koch-Strasse 40
37075 Goettingen
37075 Goettingen
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Region
Niedersachsen
Braunschweig
Göttingen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Christiane Hennecke (Mrs.)
Links
Total cost
No data
TRNAVSKA UNIVERZITA V TRNAVE
Slovakia
EU contribution
€ 399 955,00
Address
HORNOPOTOCNA 23
918 43 Trnava
918 43 Trnava
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Region
Slovensko
Západné Slovensko
Trnavský kraj
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Daniela Naništová (Mrs.)
Links
Total cost
No data
PECSI TUDOMANYEGYETEM - UNIVERSITY OF PECS
Hungary
EU contribution
€ 1 652 438,00
Address
VASVARI PAL UTCA 4
7622 Pecs
7622 Pecs
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Region
Dunántúl
Dél-Dunántúl
Baranya
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Edina Kicsindi (Mrs.)
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No data
VARSINAIS-SUOMEN SAIRAANHOITOPIIRIN KUNTAYHTYMA
Finland
EU contribution
€ 48 596,00
Address
KIINAMYLLYNKATU 4-8
20520 Turku
20520 Turku
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Region
Manner-Suomi
Etelä-Suomi
Varsinais-Suomi
Activity type
Research Organisations
Administrative Contact
Olli Tenovuo (Prof.)
Links
Total cost
No data
ICOMETRIX NV
Belgium
EU contribution
€ 2 110 000,00
Address
KOLONEL BEGAULTLAAN 1B
3012 Leuven
3012 Leuven
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Region
Vlaams Gewest
Prov. Vlaams-Brabant
Arr. Leuven
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Dirk Smeets (Dr.)
Links
Total cost
No data
ASSISTANCE PUBLIQUE HOPITAUX DE PARIS
France
EU contribution
€ 533 706,00
Address
55 BOULEVARD DIDEROT
75012 Paris
75012 Paris
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Region
Ile-de-France
Ile-de-France
Val-de-Marne
Activity type
Research Organisations
Administrative Contact
Alix Pillot (Ms.)
Links
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No data
AZIENDA OSPEDALIERA SAN GERARDO DI MONZA
Participation ended
Italy
EU contribution
No data
Address
VIA PERGOLESI 33
20052 MONZA
20052 MONZA
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Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Enzo Vigutto (Mr.)
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No data
AZIENDA SOCIO-SANITARIA TERRITORIALE (ASST) DI MONZA
Participation ended
Italy
EU contribution
€ 61 741,00
Address
VIA GIAMBATTISTA PERGOLESI 33
20900 MONZA
20900 MONZA
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Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Enzo Vigutto (Mr.)
Links
Total cost
No data
GENOME RESEARCH LIMITED
Participation ended
United Kingdom
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No data
Address
WELLCOME SANGER INSTITUTE WELLCOME GENOME CAMPUS HINXTON
CB10 1SA SAFFRON WALDEN
CB10 1SA SAFFRON WALDEN
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Region
East of England
East Anglia
Cambridgeshire CC
Activity type
Research Organisations
Administrative Contact
David Davison (Mr.)
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No data
MEDICAL RESEARCH COUNCIL
Participation ended
United Kingdom
EU contribution
No data
Address
20 Park Crescent
W1B 1AL LONDON
W1B 1AL LONDON
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Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Sylvia Richardson (Dr.)
Links
Total cost
No data
Private Universitaet Witten/Herdecke gGmbH
Germany
EU contribution
€ 376 324,00
Address
Alfred-Herrhaussen Strasse 50
58455 Witten
58455 Witten
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Region
Nordrhein-Westfalen
Arnsberg
Ennepe-Ruhr-Kreis
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Marc Maegele (Prof.)
Links
Total cost
No data
ACADEMISCH ZIEKENHUIS LEIDEN
Netherlands
EU contribution
€ 163 858,00
Address
ALBINUSDREEF 2
2333 ZA Leiden
2333 ZA Leiden
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Region
West-Nederland
Zuid-Holland
Agglomeratie Leiden en Bollenstreek
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Wilco Peul (Prof.)
Links
Total cost
No data
THE UNIVERSITY OF SHEFFIELD
United Kingdom
EU contribution
€ 401 775,00
Address
FIRTH COURT WESTERN BANK
S10 2TN Sheffield
S10 2TN Sheffield
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Region
Yorkshire and the Humber
South Yorkshire
Sheffield
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Andrew King (Mr.)
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No data
UNIVERSITE DE LIEGE
Belgium
EU contribution
€ 203 874,00
Address
PLACE DU 20 AOUT 7
4000 Liege
4000 Liege
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Region
Région wallonne
Prov. Liège
Arr. Liège
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Isabelle Halleux (Prof.)
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No data
GABO:MI GESELLSCHAFT FUR ABLAUFORGANISATION:MILLIARIUM MBH & CO KG
Participation ended
Germany
EU contribution
€ 173 130,00
Address
OSKAR VON MILLER RING 29
80333 Muenchen
80333 Muenchen
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Region
Bayern
Oberbayern
München, Kreisfreie Stadt
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Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Birgit Fuchs (Mrs.)
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No data
GREATER GLASGOW HEALTH BOARD
United Kingdom
EU contribution
€ 126 951,00
Address
GREAT WESTERN ROAD 1055 J B RUSSELL
G12 0XH Glasgow
G12 0XH Glasgow
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Region
Scotland
West Central Scotland
Glasgow City
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Brenda Colvin (Mrs.)
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No data
UNIVERSITATSKLINIKUM HEIDELBERG
Germany
EU contribution
€ 85 000,00
Address
IM NEUENHEIMER FELD 672
69120 Heidelberg
69120 Heidelberg
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Region
Baden-Württemberg
Karlsruhe
Heidelberg, Stadtkreis
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Thorsten Brietz (Mr.)
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Total cost
No data
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom
EU contribution
€ 211 676,00
Address
SOUTH KENSINGTON CAMPUS EXHIBITION ROAD
SW7 2AZ LONDON
SW7 2AZ LONDON
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Region
London
Inner London — West
Westminster
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Shaun Power (Mr.)
Links
Total cost
No data
TEKNOLOGIAN TUTKIMUSKESKUS VTT
Participation ended
Finland
EU contribution
No data
Address
TEKNIIKANTIE 4 A
02044 VTT ESPOO
02044 VTT ESPOO
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Activity type
Research Organisations
Administrative Contact
Jaana Heino (Ms.)
Links
Total cost
No data
TEKNOLOGIAN TUTKIMUSKESKUS VTT OY
Finland
EU contribution
€ 224 455,00
Address
TEKNIIKANTIE 21
02150 Espoo
02150 Espoo
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Region
Manner-Suomi
Helsinki-Uusimaa
Helsinki-Uusimaa
Activity type
Research Organisations
Administrative Contact
Jaana Heino (Ms.)
Links
Total cost
No data
THE UNIVERSITY OF STIRLING
United Kingdom
EU contribution
€ 224 684,00
Address
.
FK9 4LA Stirling
FK9 4LA Stirling
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Region
Scotland
Eastern Scotland
Perth & Kinross and Stirling
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Eric Gibb (Mr.)
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Total cost
No data
REGION HOVEDSTADEN
Denmark
EU contribution
€ 46 924,00
Address
KONGENS VAENGE 2
3400 Hillerod
3400 Hillerod
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Region
Danmark
Hovedstaden
Nordsjælland
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Administrative Contact
Martin Fabricius (Dr.)
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Total cost
No data
OSLO UNIVERSITETSSYKEHUS HF
Norway
EU contribution
€ 109 908,00
Address
KIRKEVEIEN 166 TARNBYGGET
0450 Oslo
0450 Oslo
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Region
Norge
Oslo og Viken
Oslo
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Cecilie Roe (Prof.)
Links
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No data
OXFORD BROOKES UNIVERSITY
United Kingdom
EU contribution
€ 197 230,00
Address
HEADINGTON CAMPUS GIPSY LANE
OX3 OBP Oxford
OX3 OBP Oxford
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Region
South East (England)
Berkshire, Buckinghamshire and Oxfordshire
Oxfordshire
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Higher or Secondary Education Establishments
Administrative Contact
Andrew Fleming (Mr.)
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No data
NHS BLOOD AND TRANSPLANT
United Kingdom
EU contribution
€ 22 100,00
Address
OAK HOUSE REEDS CRESCENT
WD24 4QN Watford
WD24 4QN Watford
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Region
East of England
Bedfordshire and Hertfordshire
Hertfordshire
Activity type
Research Organisations
Administrative Contact
Simon Stanworth (Dr.)
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No data
FONDAZIONE IRCCS CA' GRANDA - OSPEDALE MAGGIORE POLICLINICO
Italy
EU contribution
€ 327 000,00
Address
VIA FRANCESCO SFORZA 28
20122 Milano
20122 Milano
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Region
Nord-Ovest
Lombardia
Milano
Activity type
Other
Administrative Contact
Nino Stocchetti (Prof.)
Links
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No data
HELSINGIN YLIOPISTO
Finland
EU contribution
€ 1 391 982,00
Address
YLIOPISTONKATU 3
00014 Helsingin Yliopisto
00014 Helsingin Yliopisto
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Region
Manner-Suomi
Helsinki-Uusimaa
Helsinki-Uusimaa
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Higher or Secondary Education Establishments
Administrative Contact
Mika Frederiksen (Mr.)
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No data
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
United States
EU contribution
€ 93 225,00
Address
FRANKLIN STREET 1111 12 FLOOR
94607 OAKLAND CA
94607 OAKLAND CA
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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Mayra Sustaita (Mrs.)
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No data
UNIVERSITY OF FLORIDA
United States
EU contribution
€ 79 999,00
Address
GRINTER HALL 223
32611 5500 Gainesville
32611 5500 Gainesville
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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Kevin Wang (Dr.)
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No data
University of Cincinnati
United States
EU contribution
€ 32 000,00
Address
Cincinnati,Ohio
45221-0222 Cincinnati
45221-0222 Cincinnati
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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Carol Ross (Ms.)
Links
Total cost
No data
MONASH UNIVERSITY
Australia
EU contribution
€ 279 499,00
Address
Wellington Road
3800 Victoria
3800 Victoria
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Activity type
Higher or Secondary Education Establishments
Administrative Contact
D. James Cooper (Prof.)
Links
Total cost
No data
AUCKLAND UNIVERSITY OF TECHNOLOGY
New Zealand
EU contribution
€ 25 000,00
Address
55 WELLESLEY STREET EAST
1142 AUCKLAND
1142 AUCKLAND
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Activity type
Higher or Secondary Education Establishments
Administrative Contact
Filomena Davies (Mrs.)
Links
Total cost
No data
RENJI HOSPITAL SHANGHAI JIAOTONG UNIVERSITY SCHOOL OF MEDICINE
China
EU contribution
€ 50 000,00
Address
DONGFANG ROAD 1630
200127 SHANGHAI
200127 SHANGHAI
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Activity type
Other
Administrative Contact
Ji-Yao Jiang (Prof.)
Links
Total cost
No data
UNIVERSITAET GREIFSWALD
Germany
EU contribution
€ 19 000,00
Address
DOMSTRASSE 11
17489 Greifswald
17489 Greifswald
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Region
Brandenburg
Brandenburg
Uckermark
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Diana Lode (Mrs.)
Links
Total cost
No data
INTERNATIONALE GESELLSCHAFT ZUR ERFORSCHUNG VON HIRNTRAUMATA
Austria
EU contribution
€ 10 346,00
Address
MOLKERGASSE 3/4
1080 WIEN
1080 WIEN
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Activity type
Research Organisations
Administrative Contact
Walter Mauritz (Prof.)
Links
Total cost
No data
CHARITE - UNIVERSITAETSMEDIZIN BERLIN
Germany
EU contribution
€ 37 000,00
Address
Chariteplatz 1
10117 Berlin
10117 Berlin
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Region
Berlin
Berlin
Berlin
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Eveline Fräßdorf (Ms.)
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Total cost
No data
ARTTIC
France
EU contribution
€ 355 168,00
Address
39 RUE DES MATHURINS
75008 Paris
75008 Paris
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Region
Ile-de-France
Ile-de-France
Paris
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Martin Dietz (Dr.)
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No data
QUESGEN SYSTEMS, INC
United States
EU contribution
€ 127 500,00
Address
357 BEACH ROAD
94010 BURLINGAME
94010 BURLINGAME
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Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Michael Jarrett (Mr.)
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No data
UNIVERSITA' DEGLI STUDI DI MILANO-BICOCCA
Italy
EU contribution
€ 100 104,00
Address
PIAZZA DELL'ATENEO NUOVO 1
20126 Milano
20126 Milano
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Region
Nord-Ovest
Lombardia
Milano
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Miriam Puttini (Dr.)
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Total cost
No data