Objective The landscape of genetic testing is rapidly changing. Soon, whole genome sequence analysis (3Gb-testing) will be an effective and financially viable alternative to targeted gene analysis. New technologies that allow efficient sequencing of a whole human genome in a diagnostic setting will have an enormous impact on diagnostic centres replacing many existing molecular and cytogenetic tests.Patients deserve to benefit from our vastly growing knowledge on functional genomics. 3Gb-testing is the ideal method to bring these benefits to the public. However, it is critical to avoid mistakes with respect to ethics, quality, over or mis-interpretation of data. It is essential that our society is prepared for the change once it is implemented. Hence, current gaps in our knowledge have to be identified and research has to be initiated to bridge these gaps. The 3Gb-TEST project will bring stakeholders together and ensure they are informed with respect to the desirable and undesirable developments.The clinical utility and cost effectiveness of whole genome sequencing needs to be determined as part of a robust health technology assessment process (HTA). Interpretation of sequence data in terms of clinical relevance will pose a challenge to both laboratory and clinical geneticists. Substantial investments may be required and the logistic restructuring of genetic services will need to be addressed.This project aims to prepare Europe for innovations in molecular testing. Quality assessment schemes, HTA and guidelines have to be in place. Healthcare professionals must be aware of the impending change and potential impact on practice. The Consortium will inform the healthcare community and make recommendations to the European Commission, the European Society of Human Genetics, and national organizations relevant to this field. A key output will be a validated roadmap for the implementation of diagnostic genome sequencing in Europe. Fields of science medical and health sciencesbasic medicinemedical geneticsnatural sciencesbiological sciencesgeneticsgenomes Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH.2013.4.1-4 - Preparing the future for health research and innovation Call for proposal FP7-HEALTH-2013-INNOVATION-1 See other projects for this call Funding Scheme CSA-SA - Support actions Coordinator ACADEMISCH ZIEKENHUIS LEIDEN EU contribution € 85 921,00 Address ALBINUSDREEF 2 2333 ZA Leiden Netherlands See on map Region West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek Activity type Higher or Secondary Education Establishments Administrative Contact Egbert Bakker (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (10) Sort alphabetically Sort by EU Contribution Expand all Collapse all GENOMIC INVESTMENTS BV Netherlands EU contribution € 42 693,00 Address PLESMANLAAN 1D 2333 BZ LEIDEN See on map Region West-Nederland Zuid-Holland Agglomeratie Leiden en Bollenstreek Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Pascal Berserik (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data KATHOLIEKE UNIVERSITEIT LEUVEN Belgium EU contribution € 42 693,00 Address OUDE MARKT 13 3000 Leuven See on map Region Vlaams Gewest Prov. Vlaams-Brabant Arr. Leuven Activity type Higher or Secondary Education Establishments Administrative Contact Karolien Mariën (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data MANCHESTER UNIVERSITY NHS FOUNDATION TRUST United Kingdom EU contribution € 25 252,00 Address OXFORD ROAD M13 9WL Manchester See on map Region North West (England) Greater Manchester Manchester Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Administrative Contact Simon Patton (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data CARTAGENIA NV Belgium EU contribution € 25 252,00 Address TECHNOLOGIELAAN 3 3001 LEUVEN See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Steven Vanvooren (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data STICHTING RADBOUD UNIVERSITEIT Netherlands EU contribution € 42 693,00 Address HOUTLAAN 4 6525 XZ Nijmegen See on map Region Oost-Nederland Gelderland Arnhem/Nijmegen Activity type Higher or Secondary Education Establishments Administrative Contact Wim Van Oijen (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data THE UNIVERSITY OF MANCHESTER United Kingdom EU contribution € 88 168,00 Address OXFORD ROAD M13 9PL Manchester See on map Region North West (England) Greater Manchester Manchester Activity type Higher or Secondary Education Establishments Administrative Contact Claire Faichnie (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Salisbury NHS Foundation Trust United Kingdom EU contribution € 53 393,00 Address ODSTOCK ROAD SP2 8BJ Salisbury See on map Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Administrative Contact Chris Mattocks (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE France EU contribution € 38 734,00 Address RUE DE TOLBIAC 101 75654 Paris See on map Region Ile-de-France Ile-de-France Paris Activity type Research Organisations Administrative Contact Muriel Bouas (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON Greece EU contribution € 42 693,00 Address 6 CHRISTOU LADA STR 10561 Athina See on map Region Αττική Aττική Κεντρικός Τομέας Αθηνών Activity type Higher or Secondary Education Establishments Administrative Contact E Kafentzi (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data UNIVERSITY OF NEWCASTLE UPON TYNE United Kingdom EU contribution € 12 176,00 Address KINGS GATE NE1 7RU Newcastle Upon Tyne See on map Region North East (England) Northumberland and Tyne and Wear Tyneside Activity type Higher or Secondary Education Establishments Administrative Contact Fiona Airey (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data
