Objective "Pain-OMICS is a multidisciplinary consortium of leading clinical, academic and SME researchers in pain and different omics technologies. Genome-wide association studies identified a number of loci associated with pain, but the level of knowledge about underlying mechanisms of different pain syndromes as well as individual variation in the disease course remains inadequate. Pain-OMICS will capitalise on its existing high quality clinical, genetic, biochemical and pharmacological data and biological samples on over 5000 well characterised patients with low-back pain (LBP) and controls available to our EU and US clinical partners. We will exploit novel technological approaches made available through the expertise and global leading position of our analytical partners. These comprise cutting edge genomic, epigenomic, glycomic, and activomic approaches which reflect signal transduction and membrane dynamics. We believe that the inclusion of these complementary analyses will elucidate pathways through which acute LBP fails to resolve and becomes chronic LBP. In addition, these approaches will reveal pathways and biomarkers of chronic pain through which individual differences affects symptoms and response to therapy. Participation of leading clinics on both sides of the Atlantic will enable replication of all finding in at least three independent large cohorts, as well as in prospective study and a large twin cohort. A complex systems biology approach will be used to integrate, interrogate and understand this multidimensional dataset in order to achieve the aims of identifying novel diagnostic and prognostic biomarkers as well as new targets for therapeutic intervention. The track record of achievement of our partners coupled to participation of research-intensive SMEs is a strong indication that the ambitious work programme will be achieved and provides a framework for rapid translation of research discoveries into solutions for the benefit of large numbers of patients." Programme(s) FP7-HEALTH - Specific Programme "Cooperation": Health Topic(s) HEALTH.2013.2.2.1-5 - Understanding and controlling pain Call for proposal FP7-HEALTH-2013-INNOVATION-1 See other projects for this call Funding Scheme CP-FP - Small or medium-scale focused research project Coordinator UNIVERSITA DEGLI STUDI DI PARMA EU contribution € 1 156 980,00 Address Via universita 12 43121 Parma Italy See on map Region Nord-Est Emilia-Romagna Parma Activity type Higher or Secondary Education Establishments Administrative Contact Massimo Allegri (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (10) Sort alphabetically Sort by EU Contribution Expand all Collapse all ZIEKENHUIS OOST-LIMBURG AUTONOME VERZORGINGSINSTELLING Belgium EU contribution € 322 400,00 Address Synaps park 1 3600 Genk See on map Region Vlaams Gewest Prov. Limburg (BE) Arr. Hasselt Activity type Research Organisations Administrative Contact Joke Vanlangenaeker (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data "SPECIJALNA BOLNICA ZA ORTOPEDIJU, KIRURGIJU, NEUROLOGIJU I FIZIKALNU MEDICINU I REHABILITACIJU SVETA KATARINA USTANOVA" Croatia EU contribution € 669 300,00 Address Bracak 8 49210 Zabok See on map Activity type Research Organisations Administrative Contact Dragan Primorac (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data FONDAZIONE IRCCS POLICLINICO SAN MATTEO Italy EU contribution € 320 000,00 Address Viale golgi 19 27100 Pavia See on map Region Nord-Ovest Lombardia Pavia Activity type Research Organisations Administrative Contact Franco Marazza (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data KING'S COLLEGE LONDON United Kingdom EU contribution € 524 124,00 Address Strand WC2R 2LS London See on map Region London Inner London — West Westminster Activity type Higher or Secondary Education Establishments Administrative Contact Paul Labbett (Mr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH Germany EU contribution € 750 364,00 Address Ingolstadter landstrasse 1 85764 Neuherberg See on map Region Bayern Oberbayern München, Landkreis Activity type Research Organisations Administrative Contact Juergen Ertel (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data YURII AULCHENKO Netherlands EU contribution € 324 498,00 Address See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Yury Aulchenko (Dr.) Links Contact the organisation Opens in new window Total cost No data GENOS DOO ZA VJESTACENJE I ANALIZU Croatia EU contribution € 990 300,00 Address Drniska ulica 9 31000 Osijek See on map Region Hrvatska Panonska Hrvatska Osječko-baranjska županija Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Cizmesija Ivana (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data IP RESEARCH CONSULTING SASU France EU contribution € 359 900,00 Address Quai des deux ponts 31 93160 Noisy le grand See on map Region Ile-de-France Ile-de-France Seine-Saint-Denis Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Iain Pemberton (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data THE CENTER FOR CLINICAL RESEARCH LLC United States EU contribution € 581 020,00 Address Kimel park drive 145 suite 330 27103 Winston salem See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Leonardo Kapural (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Edith Cowan University Australia EU contribution No data Address Joondalup drive 270 6027 Joondalup See on map Activity type Higher or Secondary Education Establishments Administrative Contact Linda Penny (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data