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NOROSENSOR - A real-time monitoring system for airborne norovirus

Objective

Gastroenteritis, caused by the airborne Norovirus, is the third most deadly infectious disease worldwide, infecting ~4% of the population annually, worldwide, and has related costs measured in billions € annually in the EU alone. Today, detection of airborne viruses can only be done in retrospect in the laboratory, which severely limits the ability to rapidly react and limit the spread of an outbreak. The NOROSENSOR consortium will address this problem by developing the first of its kind, real-time sensor for airborne viruses, with particular focus on the NoV. Because the virus concentration in air can be very low, and because rapid and efficient virus trapping and concentration methods have been missing, no solution exists today. The NOROSENSOR project will fill this important need by integrating a number of recently developed, highly powerful technologies:
• Novel nanobiotechnology: nanobead enhanced rolling circle amplification (nano-RCA), engineered synthetic DNA aptamers, and proximity ligation assays (PLA)
• First ever airborne nanoparticle manipulation: capturing, filtering and up-concentration of viruses using acoustophoresis and electrostatic precipitation.
with beyond state-of-the-art:
• Ultra-sensitive QCM mass-sensitive transducers and electronics.
• Novel Off-stoichiometry Thiol-Ene-Epoxies (OSTE) polymers for cartridge and reagent storage on-chip.
The consortium consist of six of the highest ranked European Universities, each experts in their research area, two SMEs providing a unique expertise in their core business areas, and a large multinational industry in infection control technology.

Field of science

  • /natural sciences/biological sciences/microbiology/virology
  • /natural sciences/chemical sciences/polymer science
  • /social sciences/economics and business

Call for proposal

FP7-NMP-2013-SMALL-7
See other projects for this call

Funding Scheme

CP-FP - Small or medium-scale focused research project

Coordinator

KUNGLIGA TEKNISKA HOEGSKOLAN
Address
Brinellvagen 8
100 44 Stockholm
Sweden
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 772 764
Administrative Contact
Erika Appel (Mrs.)

Participants (10)

KATHOLIEKE UNIVERSITEIT LEUVEN
Belgium
EU contribution
€ 597 450
Address
Oude Markt 13
3000 Leuven
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Tine Heylen (Ms.)
STOCKHOLMS UNIVERSITET
Sweden
EU contribution
€ 305 326
Address
Universitetsvagen 10
10691 Stockholm
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Ann Nielsen (Ms.)
QCM LAB AB
Sweden
EU contribution
€ 380 800
Address
Gaddvagen 16
175 47 Jarfalla
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Lars Möller (Dr.)
LINKOPINGS UNIVERSITET
Sweden
EU contribution
€ 364 236
Address
Campus Valla
581 83 Linkoping
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Gunilla Avefeldt (Mrs.)
THE CHANCELLOR MASTERS AND SCHOLARSOF THE UNIVERSITY OF CAMBRIDGE
United Kingdom
EU contribution
€ 39 792
Address
Trinity Lane The Old Schools
CB2 1TN Cambridge
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Renata Schaeffer (Ms.)
FUTURE DIAGNOSTICS BV
Netherlands
EU contribution
€ 350 000
Address
Nieuweweg 279
6603 BN Wijchen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Mike Martens (Dr.)
KAROLINSKA INSTITUTET
Sweden
EU contribution
€ 175 800
Address
Nobels Vag 5
17177 Stockholm
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Natalie Sundberg (Ms.)
GETINGE INFECTION CONTROL AB
Sweden
EU contribution
€ 141 200
Address
Ekebergsvagen 26
305 05 Getinge
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Per Norlin (Mr.)
LOUGHBOROUGH UNIVERSITY
United Kingdom
EU contribution
€ 272 632
Address
Ashby Road
LE11 3TU Loughborough
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Christopher Malins (Dr.)
FUTURE DIAGNOSTICS SOLUTIONS BV
Netherlands
Address
Nieuweweg 279
6603 BN Wijchen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Mike Martens (Dr.)