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Breast biopsy system guided by Positron Emission Mammography allowing real-time 3D visualization of tumour lesion and needle insertion guidance for higher sampling accuracy and efficiency

Objective

Breast cancer is the most frequent cancer among women and one of the leading causes of cancer-related mortality and early diagnosis is essential to reduce the risk of mortality. First diagnostic tool is clinical imaging (mainly Mammography and Ultrasound) but suspicious findings usually require a biopsy to confirm the diagnosis; 2% of women who undergo a screening mammogram will require some type of breast biopsy (1,3 million women each year in Europe).

Breast biopsy is an image-guided procedure that can use different imaging technologies. Apart from US-guided biopsy, which is a manual procedure with limited indications, all current solutions are based on discrete scans of static images taken at different steps during the procedure. This guidance method makes current biopsy techniques to be long procedures with limited accuracy.

MAMMOCARE project will develop a PEM (Positron Emission Mammography)-guided breast biopsy system allowing real-time 3D visualization of the lesion and real-time guidance with continuous monitoring of both, lesion position and needle motion. The system will also allow for preoperative planning of the optimal needle path. Exclusive PEM technology used, having the highest sensitivity and spatial resolution in the market, will allow the detection of small lesions difficult to find with conventional morphological imaging technologies, contributing to earlier diagnosis.

Real-time monitoring and control of biopsy procedure, together with the high precision mechanics of the biopsy positioning module will assure an accurate sampling of the target lesion as well as shortening the procedure with regard to current techniques.

Thus, the consortium will offer an integral diagnosis system based on PEM Imaging, including a biopsy module compatible with this kind of imaging technology.

The consortium integrates 3 SMEs with experience in PEM imaging technology, Mechatronics applied to medical devices and Software Development. Two of the partners will become providers of their developed technologies of the third partner which will integrate the whole MAMMOCARE parts and commercialise the final product. SMEs will increase their portfolio as well as their revenues, while opening new doors to other markets thanks to the knowledge acquired.

R&D activities will be carried out by CSIC, IBV and HERI, increasing their expertise and knowledge, reinforcing new research lines and future projects. Clinical feasibility of the system will be assessed through a clinical validation study at the facilities of NKI, collaborating end-user, therefore demonstrating the MAMMOCARE contribution to defeat women breast cancer.

Field of science

  • /social sciences/economics and business/business and management/commerce
  • /natural sciences/computer and information sciences/software/software development
  • /natural sciences/physical sciences/acoustics/ultrasound
  • /natural sciences/computer and information sciences/software
  • /social sciences/sociology/demography/mortality
  • /medical and health sciences/clinical medicine/oncology/cancer
  • /medical and health sciences/clinical medicine/oncology/cancer/breast cancer
  • /engineering and technology/mechanical engineering/mechatronics

Call for proposal

FP7-SME-2013
See other projects for this call

Funding Scheme

BSG-SME - Research for SMEs

Coordinator

GENERAL EQUIPMENT FOR MEDICAL IMAGING SA
Address
Calle Jeronimo De Monsoriu, Num. 92 Planta Bj, Puerta Izq
46022 Valencia
Spain
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
EU contribution
€ 503 256,45
Administrative Contact
Jorge álamo Valenzuela (Mr.)

Participants (6)

AGENCIA ESTATAL CONSEJO SUPERIOR DEINVESTIGACIONES CIENTIFICAS
Spain
EU contribution
€ 19 229
Address
Calle Serrano 117
28006 Madrid
Activity type
Research Organisations
Administrative Contact
María ángeles López Vázquez (Ms.)
INSTITUTO DE BIOMECANICA DE VALENCIA
Spain
EU contribution
€ 15 436
Address
Camino De Vera Edificio 9C Universidad Politecnica De Valencia
46022 Valencia
Activity type
Research Organisations
Administrative Contact
María Jesús Solera (Mrs.)
THE UK HEALTH & ENVIRONMENT RESEARCH INSTITUTE LIMITED
United Kingdom
EU contribution
€ 30 518
Address
Pera Business Park Nottingham Road
LE13 0PB Melton Mowbray
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Paul Tattersall (Mr.)
VIRTUAL ANGLE BV
Netherlands
EU contribution
€ 224 277,55
Address
Keyserswey 97 C
2201 CX Noordwijk Zh
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Pedro Branco (Mr.)
STATICE SAS
France
EU contribution
€ 242 211
Address
Rue Thomas Edison 9
25000 Besancon
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Olivier Chabod (Mr.)
STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS
Netherlands
EU contribution
€ 42 072
Address
Plesmanlaan 121
1066 CX Amsterdam
Activity type
Research Organisations
Administrative Contact
Henri Van Luenen (Dr.)