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GENOMIC TOOLS FOR BREEDING AGAINST HERITABLE DISEASES IN HORSES

Objective

The project will use reliable state-of-the-art genomic technologies for the rapid identification of genetic markers for heritable diseases in horses, which will facilitate effective genomics based selection against disease susceptibility. The diseases of particular focus for this project are osteochondrosis (OC), insect bite hypersensitivity (IBH) and chronic progressive lymphedema (CPL). The occurrence of these diseases is a significant problem for horse owners and breeders and leads to poor animal welfare and severe economic losses. The initiative of this project is mainly based on the strong wish from the studbooks to obtain a genetic alternative to the more traditional breeding methods which are often not feasible in the smaller breeds. For each disease, a genetic component to disease susceptibility has been confirmed and several research groups in Europe have independently carried out small to medium-sized studies in order to find the causative genetic mechanisms underlying the disorder. However, the mode of inheritance for these diseases appears to be complex, and no genes or mutations have been identified yet, suggesting that analysis of much larger sample sizes is required or across datasets. This project aims to bring together the efforts of European research groups that are currently working on the genetics of disease susceptibility in horses. This collaboration will enable the groups to pool data for meta-analysis leading to more rapid progress in the identification of the genes and suitable gene markers for use in genomic selection against disease susceptibility. The SME associations, in close collaboration with the RTD performers, will develop breeding strategies that are optimized to the specific situation of that SME association. Once genetic markers are found, these markers will be implemented in the breeding programs of the different SME associations and can be commercialized. This will improve the competitive position of the SME partners represented by the associations. The breeding organisations will have direct access to the tests through commercial labs and through the labs they already collaborate with for their parentage control.

Call for proposal

FP7-SME-2013
See other projects for this call

Coordinator

KATHOLIEKE UNIVERSITEIT LEUVEN
Address
Oude Markt 13
3000 Leuven
Belgium
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 102 100
Administrative Contact
Tine Heylen (Ms.)

Participants (15)

BRITISH EQUESTRIAN FEDERATION LBG
United Kingdom
EU contribution
€ 240 819
Address
Stoneleigh Park National Agricultural Center
CV8 2RH Kenilworth Warwickshire
Activity type
Other
Administrative Contact
Jan Rogers (Mrs.)
KONINKLIJKE VERENIGING HET FRIESCH PAARDEN-STAMBOEK
Netherlands
EU contribution
€ 250 484
Address
Oprijlaan 1
9205 BZ Drachten
Activity type
Other
Administrative Contact
Ids Hellinga (Mr.)
SVENSKA ISLANDSHASTFORBUNDET
Sweden
EU contribution
€ 173 000
Address
Ridsportens Hus
734 94 Stromsholm
Activity type
Other
Administrative Contact
Göran Montan (Mr.)
BELGISCH WARMBLOEDPAARD/CHEVAL DE SANG BELGE/BELGISCHES WARMBLUTPFERDGOE BWP VZW
Belgium
EU contribution
€ 163 820
Address
Waversebaan 99
3050 Oud Heverlee
Activity type
Other
Administrative Contact
Rudi Eerdekens (Mr.)
SVENSKA HASTAVELSFORBUNDET
Sweden
EU contribution
€ 245 820
Address
Grabrodragatan 1
532 24 Skara
Activity type
Other
Administrative Contact
Christina Storm (Mrs.)
KONINKLIJKE MAATSCHAPPIJ HET BELGISCH TREKPAARD VZW
Belgium
EU contribution
€ 11 820
Address
Algemeen Stemrechtlaan 49
1030 Brussel
Activity type
Other
Administrative Contact
Jan De Boitselier (Mr.)
BRONDEEL MAARTEN EN DONAAT LV
Belgium
EU contribution
€ 52 337,75
Address
Breemeersen 36
9880 Lotenhulle Aalter
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Maarten Brondeel (Mr.)
STAL GROENEWEG BV
Netherlands
EU contribution
€ 52 337,75
Address
Groeneweg 28A
1861 PH Bergen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Cees Roozemond (Mr.)
SUNDQVIST MARIE CHARLOTTE HELENA
Sweden
EU contribution
€ 52 337
Address
Vialmvagen 5
387 91 Borgholm
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Marie Sundquist (Dr.)
DR. VAN HAERINGEN LABORATORIUM BV
Netherlands
EU contribution
€ 108 700
Address
Agro Business Park 100
6708 PW Wageningen
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Wim Van Haeringen (Dr.)
ANIMAL HEALTH TRUST

Participation ended

United Kingdom
Address
Lanwades Park Kentford
CB8 7UU Suffolk
Activity type
Research Organisations
Administrative Contact
Caroline Reynolds (Dr.)
WAGENINGEN UNIVERSITY
Netherlands
Address
Droevendaalsesteeg 4
6708 PB Wageningen
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Gerda Bakker (Ms.)
SVERIGES LANTBRUKSUNIVERSITET
Sweden
EU contribution
€ 3 114,83
Address
Almas Alle 8
750 07 Uppsala
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Helena Pettersson (Mrs.)
THE UNIVERSITY OF NOTTINGHAM
United Kingdom
EU contribution
€ 1 936,86
Address
University Park
NG7 2RD Nottingham
Activity type
Higher or Secondary Education Establishments
Administrative Contact
Paul Cartledge (Mr.)
DIEPENSTEYN NV
Belgium
EU contribution
€ 40 640
Address
Brouwerijstraat 1
1840 Londerzeel
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Administrative Contact
Geert Van De Voorde (Mr.)