Project description Heterogeneous Integration and take-up of of Key Enabling Technologies for Components and Systems Show the project objective Hide the project objective Through further development, integration and validation of micro-nano-bio and biophotonics systems from previous projects CanDo will develop an instrument that will permit the identification and concentration determination of rare cells in peripheral blood for two key societal challenges, early and low cost anti-cancer drug efficacy determination and cancer diagnosis/monitoring.A cellular link between the primary malignant tumor and the peripheral metastases, responsible for 90% of cancer-related deaths, has been established in the form of circulating tumor cells (CTCs) in peripheral blood. Furthermore the relatively short survival time of CTCs in peripheral blood means that their detection is indicative of tumor progression thereby providing in addition to a prognostic value an evaluation of therapeutic efficacy and early recognition of tumor progression in theranostics. In cancer patients however blood concentrations are very low (=1 CTC/1E9 cells) and current detection strategies are too insensitive, limiting use to prognosis of only those with advanced metastatic cancer. Similarly problems occur in therapeutics with anti-cancer drug development leading to lengthy and costly trials often preventing access to market. There is therefore a clear need for a novel analytical platform capable of highly reproducible and reliable identification of CTC concentrations of interest in an easily accessible format.With all relevant industrial stakeholders and users onboard CanDo is uniquely capable of delivering such a platform. Its novel cell separation/SERS analysis technologies plus nucleic acid based molecular characterization will provide an accurate CTC count with high throughput and high yield meeting both key societal challenges. Being beyond the state of art it will lead to substantial share gains not just in the high end markets of drug discovery and cancer diagnostics but due to modular technologies in others e.g. transport, security and safety and environment. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverynatural sciencesbiological sciencesbiochemistrybiomoleculesnucleic acidsmedical and health sciencesclinical medicineoncology Programme(s) FP7-ICT - Specific Programme "Cooperation": Information and communication technologies Topic(s) ICT-2013.3.3 - Heterogeneous Integration and take-up of Key Enabling Technologies for Components and Systems Call for proposal FP7-ICT-2013-10 See other projects for this call Funding Scheme CP - Collaborative project (generic) Coordinator UNIVERSITAT DE VALENCIA EU contribution € 501 501,00 Address AVENIDA BLASCO IBANEZ 13 46010 Valencia Spain See on map Region Este Comunitat Valenciana Valencia/València Activity type Higher or Secondary Education Establishments Administrative Contact Angeles Sanchis (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Participants (9) Sort alphabetically Sort by EU Contribution Expand all Collapse all INTERUNIVERSITAIR MICRO-ELECTRONICA CENTRUM Belgium EU contribution € 461 833,00 Address KAPELDREEF 75 3001 Leuven See on map Region Vlaams Gewest Prov. Vlaams-Brabant Arr. Leuven Activity type Research Organisations Administrative Contact Christine Van Houtven (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data Bayer Pharma AG Germany EU contribution € 253 685,00 Address Muellerstrasse 178 13353 Berlin See on map Region Berlin Berlin Berlin Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Thomas Krahn (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data LEIBNIZ-INSTITUT FUER PHOTONISCHE TECHNOLOGIEN E.V. Germany EU contribution € 311 013,00 Address Albert Einstein strasse 9 07745 Jena See on map Region Thüringen Thüringen Jena, Kreisfreie Stadt Activity type Research Organisations Administrative Contact Gabriele Hamm (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data GILUPI GMBH Germany EU contribution € 290 946,00 Address AM MUEHLENBERG 11 14476 Postdam See on map Region Brandenburg Brandenburg Potsdam Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Klaus Luecke (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data MICROFLUIDIC CHIPSHOP GMBH Germany EU contribution € 496 857,00 Address STOCKHOLMER STRASSE 20 07747 Jena See on map Region Thüringen Thüringen Jena, Kreisfreie Stadt Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Claudia Gärtner (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data IKERLAN S. COOP Spain EU contribution € 391 264,00 Address P JOSE MARIA ARIZMENDIARRIETA 2 20500 Mondragon See on map Region Noreste País Vasco Gipuzkoa Activity type Research Organisations Administrative Contact Chris Merveille (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data STOCKHOLMS UNIVERSITET Sweden EU contribution € 400 312,00 Address UNIVERSITETSVAGEN 10 10691 Stockholm See on map Region Östra Sverige Stockholm Stockholms län Activity type Higher or Secondary Education Establishments Administrative Contact Ann Nielsen (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data KUNGLIGA TEKNISKA HOEGSKOLAN Sweden EU contribution € 549 409,00 Address BRINELLVAGEN 8 100 44 Stockholm See on map Region Östra Sverige Stockholm Stockholms län Activity type Higher or Secondary Education Establishments Administrative Contact Marianne Fridborn (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Total cost No data REGION STOCKHOLM Sweden EU contribution € 343 180,00 Address HANTVERKARGATAN 45 104 22 Stockholm See on map Region Östra Sverige Stockholm Stockholms län Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Administrative Contact Erica Oeqvist Links Contact the organisation Opens in new window Website Opens in new window Total cost No data