Objective Alzheimer’s disease (AD) is the major cause of dementia which has no cure at the moment. The overall aim of the work described in this proposal is to create a long-term strategic partnership between Sheffield University (UK), Lisbon University (Portugal), Eli Lilly (UK) and Biofordrug (Italy) in order to develop chemical biology tools for better understanding the role of PrPC in AD and harnessing this understanding to develop novel chemical entities for diagnostic and therapeutics applications.The D3i4AD project brings together a consortium of groups with internationally-leading expertise from academia and industries in chemistry, molecular design and modelling, biochemistry, diagnostic and drug development. Our proposed programme will lead to major increases in the knowledge and capacity of all consortium members, achieved through significant intersectoral exchange of personnel between the partners over the duration of the project (total 134 person months) and through temporary recruitment of 5 new experienced researchers (total 114 person months). The project will thus underpin a substantial programme of intersectoral knowledge transfer and research training and lead to significant innovation and advances in several areas of basic research as well as diagnostics and therapeutics development. These activities will strongly enhance EU standing and international competitiveness in this extremely challenging and increasingly important technological area. Fields of science medical and health sciencesbasic medicinepharmacology and pharmacydrug discoverynatural sciencesbiological sciencesbiochemistrymedical and health sciencesbasic medicineneurologydementiaalzheimer Programme(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Topic(s) FP7-PEOPLE-2013-IAPP - Marie Curie Action: "Industry-Academia Partnerships and Pathways" Call for proposal FP7-PEOPLE-2013-IAPP See other projects for this call Funding Scheme MC-IAPP - Industry-Academia Partnerships and Pathways (IAPP) Coordinator THE UNIVERSITY OF SHEFFIELD Address Firth court western bank S10 2TN Sheffield United Kingdom See on map Region Yorkshire and the Humber South Yorkshire Sheffield Activity type Higher or Secondary Education Establishments Administrative Contact Andrew King (Mr.) Links Contact the organisation Opens in new window Website Opens in new window EU contribution No data Participants (4) Sort alphabetically Sort by EU Contribution Expand all Collapse all ELI LILLY AND COMPANY LTD United Kingdom EU contribution € 290 164,16 Address Lilly house basingview RG21 4FA Basingstoke See on map Region South East (England) Hampshire and Isle of Wight North Hampshire Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Magnus W.Walter (Dr.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data BIOFORDRUG SRL Italy EU contribution € 449 415,60 Address Via edoardo orabona 4 dip farmaco chimico univ bari 70125 Bari See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Nicola Antonio Colabufo (Prof.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data FACULDADE DE CIENCIAS DA UNIVERSIDADE DE LISBOA Portugal EU contribution € 399 591,50 Address Campo grande c5 piso 3 1749-016 Lisboa See on map Region Continente Área Metropolitana de Lisboa Área Metropolitana de Lisboa Activity type Higher or Secondary Education Establishments Administrative Contact Gomes Silvia (Mrs.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data AMORFIX LIFE SCIENCES LTD Canada EU contribution € 60 591,75 Address American drive 3403 M2N 2M6 Mississauga on See on map Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Administrative Contact Janet Clennett (Ms.) Links Contact the organisation Opens in new window Website Opens in new window Other funding No data
