Final Report Summary - RARITOR (mTOR pathophysiology in rare human diseases)
1) How caloric restriction may delay senescence and ageing.
2) How lipid accumulation in liver may contribute to cancer development.
3) What is the origin of rhabdomyolysis and lipid accumulation in lipin1 deficiency
4) Why aberrant mTOR activation may also trigger seizures and polycystic kidney, as observed in several genetic diseases.