Objective
BEDimplants project represents an innovative concept in oral implantology based on a multidisciplinary approach in periodontal regenerative medicine and tissue engineering that has the potential to significantly influence the outcome of medical and dental therapies. The project aims to develop novel biomimetic engineered dental implants (BEDimplants) that self-promote the regeneration of periodontal ligament (PDL) and provide in a single implant therapy the adequate environment to promote specific cell lineages, such as primary human gingival fibroblast (hGF) and dental pulp stem cells (hDPSC), to integrate, differentiate and proliferate within an artificial biomimetic extracellular matrix (aECM). The utilization of natural products and biomolecules present in the native periodontal ECM such as collagen, hyaluronic acid and cell signaling molecules, BMPs and TGFbs, to be grafted onto titanium surfaces is presented as a promising approach to the development of novelty implantable devices that mimic the complexity of ECM which can be reabsorbed or degraded by the organism after their implantation. Furthermore, self-crosslinkable bioactive peptide sequences (RGD and DGEA) can be synthesized and chemically linked to those biomolecules tailoring their biofunctionality and providing a biomimetic three-dimensional aECM-g-Ti scaffold that can be implanted in the presence of the appropriate cell cocktail that fulfill all the requirements of PDL tissue engineering.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine odontology dental implantology
- natural sciences biological sciences biochemistry biomolecules
- medical and health sciences medical biotechnology tissue engineering
- medical and health sciences medical biotechnology cells technologies stem cells
- medical and health sciences medical biotechnology implants
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-IEF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
WC2R 2LS London
United Kingdom
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.