Objective
Successful pathogens often induce plant developmental pathways to suppress plant defence. As a result, diseased plants frequently display symptoms such as hypertrophy, hyperplasia, hypocotyls elongation and increase of bushiness. Plasmodiophora brassicae is such a pathogen. P.brassicae is a biotrophic fungus, the causal agent of clubroot disease of brassica and Arabidopsis. This disease is characterized by the production of galls on the root of the plant. To produce the gall, the pathogen induces the local accumulation of two phytohormones: auxin and cytokinin in plant roots. These hormones activate the division and the enlargement of meristematic root cells resulting in the production of this “new organ”. Previous studies demonstrated that auxin and cytokinin are able to suppress the induction of salicylic acid (SA), which controls the main defence pathway against biotrophic pathogen. Using both pathogen-free and Arabidopsis-P.brassica experimental systems, I aim to understand the mechanism by which auxin and cytokinin interact with SA signalling in roots, and how the induction of a developmental program interferes with SA signalling. I will first examine which parts of the auxin and cytokinin pathways are required to suppress SA and to promote P.brassicae virulence. In addition to the perception of phytohormones (auxin and cytokinin for example) the induction of the developmental program is controlled by the presence of “master regulator”, often transcription factors, and epigenetic modification of the DNA. Thus, next, I will examine the involvement of the key transcription factors and epigenetic modification in the suppression of SA signalling and in P.brassicae virulence. The project will improve our knowledge on the cross talk between growth hormones and plant defence against pathogens and will contribute to develop a new generation of resistant plants.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences biological sciences genetics DNA
- natural sciences biological sciences microbiology mycology
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-IEF
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Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
75007 PARIS CEDEX 07
France
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.