Objetivo Basic processes within individual cells are integrated as part of the development and function of entire multicellular organisms. How this global coordination is achieved is a central question in biology. Plants use silencing small (s)RNA to control physiological and defensive processes at both the cellular and organismal levels by trafficking sRNAs from cell-to-cell through plasmodesmata and over long distances through the phloem. However, the parameters and mechanisms controlling the movement of plant small interfering RNAs (siRNAs) and micro RNAs (miRNAs) remain poorly understood and may well vary extensively depending on the cell types involved, quantities and biochemical nature of sRNAs. Combining biochemical, molecular and genetic approaches, the proposed project aims at deciphering the specific mechanisms underpinning viral, artificial and endogenous sRNA movement. The project is expected to generate a wealth of original information and significantly improve our understanding of RNA silencing in plants and perhaps other organisms. Ámbito científico natural sciencesbiological sciencesgeneticsRNA Programa(s) FP7-PEOPLE - Specific programme "People" implementing the Seventh Framework Programme of the European Community for research, technological development and demonstration activities (2007 to 2013) Tema(s) FP7-PEOPLE-2013-IEF - Marie-Curie Action: "Intra-European fellowships for career development" Convocatoria de propuestas FP7-PEOPLE-2013-IEF Consulte otros proyectos de esta convocatoria Régimen de financiación MC-IEF - Intra-European Fellowships (IEF) Coordinador EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH Aportación de la UE € 199 317,60 Dirección Raemistrasse 101 8092 Zuerich Suiza Ver en el mapa Región Schweiz/Suisse/Svizzera Zürich Zürich Tipo de actividad Higher or Secondary Education Establishments Contacto administrativo Olivier Voinnet (Prof.) Enlaces Contactar con la organización Opens in new window Sitio web Opens in new window Coste total Sin datos