Objective
The current proposal ChiralMOF has the aim to develop rationally designed novel nanoporous materials for the separation of enantiomers. The separation of enantiomers is of great importance to industry in the domain of medicine. New treatments often rely on medication consisting of pure enantiomers. Enantiomers separation is extremely challenging as the molecules are nearly identical (shape and properties) and is achieved at great cost by relying on expensive, time consuming and complex processes. Separation through adsorption using chiral stationary phases is a viable alternative to the current technology.
It is the aim of the project to develop novel porous materials that allow for fast, efficient and inexpensive separation of enantiomers. In the past decade, a new class of porous materials was developed: metal-organic frameworks. This new class of materials can be rationally designed, exhibits highly specific properties and may be economically viable and a stable alternative to classical stationary phases. Surprisingly, very little attention has been devoted to the design of homochiral metal-organic frameworks for enantiomer separation. The chiral structure of these metal-organic frameworks favours the interaction with one specific enantiomer. The preferential interaction, adsorption, is the basis for an efficient chromatographic purification process.
A combination of theoretical and experimental work is proposed. Advanced molecular simulations allow for the rational design of novel structures and prediction of the adsorption, separation potential of these nanoporous materials. Computational screening of hypothetical structures is a fast and efficient tool to identify high potential structures. A selected set of promising structures will be synthesized, characterized and validated using state of the art equipment. The validated structures shall be put to a test to assess their potential as stationary phases and stability in industrially realistic conditions.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pharmacology and pharmacy pharmaceutical drugs
- engineering and technology chemical engineering separation technologies
You need to log in or register to use this function
We are sorry... an unexpected error occurred during execution.
You need to be authenticated. Your session might have expired.
Thank you for your feedback. You will soon receive an email to confirm the submission. If you have selected to be notified about the reporting status, you will also be contacted when the reporting status will change.
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP7-PEOPLE-2013-IOF
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
1050 BRUSSEL
Belgium
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.