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Platform for ultra-sensitive Point-of-Care diagnostics for Infectious Diseases

Objective

The aim of the PoC-ID project is to develop new micro- and nanoelectronic-based sensing and integration concepts for advanced miniaturised in vitro diagnostic devices. The project addresses the increasing demand for rapid and ultra-sensitive point-of-care diagnostics to reduce healthcare costs and increase the quality of life with a focus on infectious diseases, one of the world’s leading causes of morbidity and death. Interdisciplinary collaboration using the technology and expertise of the consortium members will be applied to develop and test a breakthrough PoC prototype for the diagnosis of respiratory syncytial virus infections and host responses in the paediatric context. PoC-ID will enable new types of point-of-care diagnostics for virtually any type of complex liquid sample. Applications are disease diagnosis, monitoring of therapeutic responses, clinical research of pathogen-host interaction and personalised medicine. The platform technology can easily be adapted to a variety of diagnostic or biosensing purposes, such as in health/environmental monitoring or food quality testing. PoC-ID will combine the detection of both pathogens and host responses leading to more accurate diagnosis as compared to the current standard which is focused on detection of pathogens only. This novel approach will support prevention and control of pathogen spread and enable faster and more personalised patient treatment. Improved performance in terms of robustness, sensitivity and selectivity will be reached by a combination of innovative nanomembrane technology, molecular engineered capture molecules and two novel sensing concepts. Further advances will be realised in terms of usability and speed of data-analysis arising from the integration of sensors, read-out electronics and microfluidics into one user friendly point-of-care (PoC) platform. Costs of the new disposable sensors will be ultra-low at high volumes, thanks to designing into microelectronics production flows.

Call for proposal

H2020-PHC-2014-two-stage
See other projects for this call

Funding Scheme

RIA - Research and Innovation action

Coordinator

TECHNISCHE UNIVERSITAT BERLIN
Address
Strasse Des 17 Juni 135
10623 Berlin
Germany
Activity type
Higher or Secondary Education Establishments
EU contribution
€ 1 315 125

Participants (13)

CNM TECHNOLOGIES GMBH
Germany
EU contribution
€ 397 897,50
Address
Morgenbreede 1
33615 Bielefeld
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
VAN HEEREN ARIE HENDRIK
Netherlands
EU contribution
€ 81 112
Address
Drakensteynlaan 34
3319 RG Dordrecht
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
Germany
EU contribution
€ 829 803,75
Address
Hansastrasse 27C
80686 Munchen
Activity type
Research Organisations
MERCENE LABS AB
Sweden
EU contribution
€ 115 000
Address
Teknikringen 38
114 28 Stockholm
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
MICROPATHOLOGY LIMITED
United Kingdom
EU contribution
€ 118 625
Address
Sir William Lyons Road
CV4 7EZ Coventry
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
NOXXON PHARMA AG

Participation ended

Germany
EU contribution
€ 387 926,06
Address
Max Dohrn Strasse 8 10
10589 Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
STICHTING RADBOUD UNIVERSITEIT
Netherlands
EU contribution
€ 693 432,50
Address
Houtlaan 4
6525 XZ Nijmegen
Activity type
Higher or Secondary Education Establishments
SIGNALGENERIX LIMITED
Cyprus
EU contribution
€ 323 000
Address
Grigori Afxentiou 23C Mesa Geitonia
4003 Limassol
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
FRIEDRICH-SCHILLER-UNIVERSITAT JENA
Germany
EU contribution
€ 666 906
Address
Furstengraben 1
07743 Jena
Activity type
Higher or Secondary Education Establishments
SERVIZO GALEGO DE SAUDE
Spain
EU contribution
€ 214 606
Address
Edificio Administrativo San Lázaro
15703 Santiago De Compostela
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
MEMSOP CONSULTING
Romania
EU contribution
€ 64 000
Address
Sat Vidra
627415 Vidra Vrancea
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
enablingMNT GMBH
Germany
EU contribution
€ 320 753,94
Address
Holsteinische Str 23
12161 Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
APTARION BIOTECH AG
Germany
EU contribution
€ 434 945
Address
Max Dohrn Str 8-10
10589 Berlin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)