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Platform for ultra-sensitive Point-of-Care diagnostics for Infectious Diseases

Obiettivo

The aim of the PoC-ID project is to develop new micro- and nanoelectronic-based sensing and integration concepts for advanced miniaturised in vitro diagnostic devices. The project addresses the increasing demand for rapid and ultra-sensitive point-of-care diagnostics to reduce healthcare costs and increase the quality of life with a focus on infectious diseases, one of the world’s leading causes of morbidity and death. Interdisciplinary collaboration using the technology and expertise of the consortium members will be applied to develop and test a breakthrough PoC prototype for the diagnosis of respiratory syncytial virus infections and host responses in the paediatric context. PoC-ID will enable new types of point-of-care diagnostics for virtually any type of complex liquid sample. Applications are disease diagnosis, monitoring of therapeutic responses, clinical research of pathogen-host interaction and personalised medicine. The platform technology can easily be adapted to a variety of diagnostic or biosensing purposes, such as in health/environmental monitoring or food quality testing. PoC-ID will combine the detection of both pathogens and host responses leading to more accurate diagnosis as compared to the current standard which is focused on detection of pathogens only. This novel approach will support prevention and control of pathogen spread and enable faster and more personalised patient treatment. Improved performance in terms of robustness, sensitivity and selectivity will be reached by a combination of innovative nanomembrane technology, molecular engineered capture molecules and two novel sensing concepts. Further advances will be realised in terms of usability and speed of data-analysis arising from the integration of sensors, read-out electronics and microfluidics into one user friendly point-of-care (PoC) platform. Costs of the new disposable sensors will be ultra-low at high volumes, thanks to designing into microelectronics production flows.

Invito a presentare proposte

H2020-PHC-2014-two-stage
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Meccanismo di finanziamento

RIA - Research and Innovation action

Coordinatore

TECHNISCHE UNIVERSITAT BERLIN
Indirizzo
Strasse Des 17 Juni 135
10623 Berlin
Germania
Tipo di attività
Higher or Secondary Education Establishments
Contributo UE
€ 1 315 125

Partecipanti (13)

CNM TECHNOLOGIES GMBH
Germania
Contributo UE
€ 397 897,50
Indirizzo
Morgenbreede 1
33615 Bielefeld
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
VAN HEEREN ARIE HENDRIK
Paesi Bassi
Contributo UE
€ 81 112
Indirizzo
Drakensteynlaan 34
3319 RG Dordrecht
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
FRAUNHOFER GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V.
Germania
Contributo UE
€ 829 803,75
Indirizzo
Hansastrasse 27C
80686 Munchen
Tipo di attività
Research Organisations
MERCENE LABS AB
Svezia
Contributo UE
€ 115 000
Indirizzo
Teknikringen 38
114 28 Stockholm
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
MICROPATHOLOGY LIMITED
United Kingdom
Contributo UE
€ 118 625
Indirizzo
Sir William Lyons Road
CV4 7EZ Coventry
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
NOXXON PHARMA AG

Partecipazione conclusa

Germania
Contributo UE
€ 387 926,06
Indirizzo
Max Dohrn Strasse 8 10
10589 Berlin
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
STICHTING RADBOUD UNIVERSITEIT
Paesi Bassi
Contributo UE
€ 693 432,50
Indirizzo
Houtlaan 4
6525 XZ Nijmegen
Tipo di attività
Higher or Secondary Education Establishments
SIGNALGENERIX LIMITED
Cipro
Contributo UE
€ 323 000
Indirizzo
Grigori Afxentiou 23C Mesa Geitonia
4003 Limassol
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
FRIEDRICH-SCHILLER-UNIVERSITAT JENA
Germania
Contributo UE
€ 666 906
Indirizzo
Furstengraben 1
07743 Jena
Tipo di attività
Higher or Secondary Education Establishments
SERVIZO GALEGO DE SAUDE
Spagna
Contributo UE
€ 214 606
Indirizzo
Edificio Administrativo San Lázaro
15703 Santiago De Compostela
Tipo di attività
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
MEMSOP CONSULTING
Romania
Contributo UE
€ 64 000
Indirizzo
Sat Vidra
627415 Vidra Vrancea
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
enablingMNT GMBH
Germania
Contributo UE
€ 320 753,94
Indirizzo
Holsteinische Str 23
12161 Berlin
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)
APTARION BIOTECH AG
Germania
Contributo UE
€ 434 945
Indirizzo
Max Dohrn Str 8-10
10589 Berlin
Tipo di attività
Private for-profit entities (excluding Higher or Secondary Education Establishments)