Deliverables Documents, reports (19) Project guideline document Project guideline document 3rd Report from the Scientific Advisory Board meeting Report from the SAB regarding the project's progress during the third year. Report on critical EDC mixtures I Report on critical EDC mixtures for the three health domains in the SELMA and the Life Child study modelled with covariates and potential confounders (mixtures I). Report on doses and exposure regiments for experimental studies with mixtures 0 Report on doses and exposure regiments for experimental studies with mixtures 0. Mixture 0 is based on a Bio-statistical model (pre-study on existing data) including prenatal EDC exposure for a subset of EDCs (10 phthalate metabolites, 2 phenols and 8 PFCs) and health outcomes at 2.5 years of age in the three health domains. 1st Report from Scientific Advisory Board meeting Report from the SAB regarding the project's progress during the first year. Report on inclusive strategies for the regulatory implementation of risk assessment tools for EDC mixtures Report on inclusive strategies for the regulatory implementation of risk assessment tools for EDC mixtures 2nd Dissemination activity and quality report Report on the activity and quality of dissemination during the second half of the project. Report EDC mixtures III Report on final biostatistical models for identifying critical EDC mixtures including covariates and potential confounders, new biomarkers, genetic/epigenetic analyses and new biomarkers (mixtures III). 1st Dissemination activity and quality report Report on the activity and quality of dissemination during the first half of the project. Report on how to ensure workability of the IPCS definition of EDCs Report on how to ensure workability of the IPCS definition of EDCs. Report on chemical levels in SELMA and Life Child. Report on measured levels of chemicals in serumplasma and urine of mothers in SELMA and Life Child Report on a novel framework for risk assessment of mixtures Report on a novel framework for risk assessment of mixtures Dissemination guideline Guideline on the dissemination of information and results generated within EDC-MixRisk. Meeting report of the WHO Chemical Risk Assessment Network Meeting report of the WHO Chemical Risk Assessment Network Whitepaper on EDCs and health risks Whitepaper on EDCs and health risks 4th Report from the Scientific Advisory Board meeting Report from the SAB regarding the project's progress during the fourth year. Internal communication plan document Document about the internal communication plan Report on doses and exposure regiments for experimental studies with mixtures I Report on doses and exposure regiments for experimental studies with mixtures I. Mixture I on a Bio-statistical model including prenatal EDC exposure (full data set), and health outcome data at 7 years of age, and potential confounders in SELMA and LIFE Child. 2nd Report from the Scientific Advisory Board meeting Report from the SAB regarding the project's progress during the second year. Websites, patent fillings, videos etc. (2) Comprehensive information about ECD-MixRisk in EN, SE, FR, DE, FI, GR, IT Comprehensive information about ECD-MixRisk in EN, SE, FR, DE, FI, GR, IT Launch of webpage Launch of project webpage. Open Research Data Pilot (1) Data management plan document Document about the data management plan Publications Peer reviewed articles (14) Marked for Life: Epigenetic Effects of Endocrine Disrupting Chemicals Author(s): Miriam N. Jacobs, Emma L. Marczylo, Carlos Guerrero-Bosagna, Joëlle Rüegg Published in: Annual Review of Environment and Resources, Issue 42/1, 2017, Page(s) 105-160, ISSN 1543-5938 Publisher: Annual Reviews, Inc. DOI: 10.1146/annurev-environ-102016-061111 Understanding Epigenetic Effects of Endocrine Disrupting Chemicals: From Mechanisms to Novel Test Methods Author(s): Ali Alavian-Ghavanini, Joëlle Rüegg Published in: Basic & Clinical Pharmacology & Toxicology, Issue 122/1, 2018, Page(s) 38-45, ISSN 1742-7835 Publisher: Nordic Pharmacological Society DOI: 10.1111/bcpt.12878 Endokrine Modulatoren Author(s): M. Hoffmann, S. Gebauer, M. Nüchter, R. Baber, J. Ried, M. von Bergen, W. Kiess Published in: Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz, Issue 60/6, 2017, Page(s) 640-648, ISSN 1436-9990 Publisher: Springer Verlag DOI: 10.1007/s00103-017-2551-8 Androgenic potential of human fetal adrenals at the end of the first trimester Author(s): I Savchuk, M L Morvan, J P Antignac, K Gemzell-Danielsson, B Le Bizec, O Söder, K Svechnikov Published in: Endocrine Connections, Issue 6/6, 2017, Page(s) 348-359, ISSN 2049-3614 Publisher: BioScientifica Ltd. DOI: 10.1530/EC-17-0085 Human amniotic fluid contaminants alter thyroid hormone signalling and early brain development in Xenopus embryos Author(s): Jean-Baptiste Fini, Bilal B. Mughal, Sébastien Le Mével, Michelle Leemans, Mélodie Lettmann, Petra Spirhanzlova, Pierre Affaticati, Arnim Jenett, Barbara A. Demeneix Published in: Scientific Reports, Issue 7, 2017, Page(s) 43786, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/srep43786 Uppsala Consensus Statement on Environmental Contaminants and the Global Obesity Epidemic Author(s): Lars Lind, P. Monica Lind, Margareta H. Lejonklou, Linda Dunder, Åke Bergman, Carlos Guerrero-Bosagna, Erik Lampa, Hong Kyu Lee, Juliette Legler, Angel Nadal, Youngmi Kim Pak, Richard P. Phipps, Laura N. Vandenberg, Daniel Zalko, Marlene Ågerstrand, Mattias Öberg, Bruce Blumberg, Jerrold J. Heindel, Linda S. Birnbaum Published in: Environmental Health Perspectives, Issue 124/5, 2016, ISSN 0091-6765 Publisher: US Department of Health and Human Services DOI: 10.1289/ehp.1511115 Effects of pre- and post-natal exposure to bisphenol A on the stress system Author(s): E. Kitraki, I. Nalvarte, A. Alavian-Ghavanini, J. Rüegg Published in: Endocrine Disruptors, Issue 4/1, 2016, Page(s) e1184775, ISSN 2327-3747 Publisher: Taylor & Francis DOI: 10.1080/23273747.2016.1184775 Scientific principles for the identification of endocrine-disrupting chemicals: a consensus statement Author(s): Roland Solecki, Andreas Kortenkamp, Åke Bergman, Ibrahim Chahoud, Gisela H. Degen, Daniel Dietrich, Helmut Greim, Helen Håkansson, Ulla Hass, Trine Husoy, Miriam Jacobs, Susan Jobling, Alberto Mantovani, Philip Marx-Stoelting, Aldert Piersma, Vera Ritz, Remy Slama, Ralf Stahlmann, Martin van den Berg, R. Thomas Zoeller, Alan R. Boobis Published in: Archives of Toxicology, 2016, ISSN 0340-5761 Publisher: Springer Verlag DOI: 10.1007/s00204-016-1866-9 Thyroid-disrupting chemicals and brain development: an update Author(s): Bilal B Mughal, Jean-Baptiste Fini, Barbara A Demeneix Published in: Endocrine Connections, Issue 7/4, 2018, Page(s) R160-R186, ISSN 2049-3614 Publisher: BioScientifica Ltd. DOI: 10.1530/EC-18-0029 Prenatal Bisphenol A Exposure is Linked to Epigenetic Changes in Glutamate Receptor Subunit Gene Grin2b in Female Rats and Humans Author(s): Ali Alavian-Ghavanini, Ping-I Lin, P. Monica Lind, Sabina Risén Rimfors, Margareta Halin Lejonklou, Linda Dunder, Mandy Tang, Christian Lindh, Carl-Gustaf Bornehag, Joëlle Rüegg Published in: Scientific Reports, Issue 8/1, 2018, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-018-29732-9 Current EU research activities on combined exposure to multiple chemicals Author(s): Stephanie K. Bopp, Robert Barouki, Werner Brack, Silvia Dalla Costa, Jean-Lou C.M. Dorne, Paula E. Drakvik, Michael Faust, Tuomo K. Karjalainen, Stylianos Kephalopoulos, Jacob van Klaveren, Marike Kolossa-Gehring, Andreas Kortenkamp, Erik Lebret, Teresa Lettieri, Sofie Nørager, Joëlle Rüegg, Jose V. Tarazona, Xenia Trier, Bob van de Water, Jos van Gils, Åke Bergman Published in: Environment International, Issue 120, 2018, Page(s) 544-562, ISSN 0160-4120 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.envint.2018.07.037 Gestational exposure to an epidemiologically defined mixture of phthalates leads to gonadal dysfunction in mouse offspring of both sexes Author(s): Anastasia Repouskou, Emily Panagiotidou, Lydia Panagopoulou, Pernilla Larsdotter Bisting, Astrud R. Tuck, Marcus O. D. Sjödin, Johan Lindberg, Evangelos Bozas, Joëlle Rüegg, Chris Gennings, Carl-Gustaf Bornehag, Pauliina Damdimopoulou, Antonios Stamatakis, Efthymia Kitraki Published in: Scientific Reports, Issue 9/1, 2019, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-019-42377-6 A Novel Approach to Chemical Mixture Risk Assessment—Linking Data from Population‐Based Epidemiology and Experimental Animal Tests Author(s): Carl‐Gustaf Bornehag, Efthymia Kitraki, Antonios Stamatakis, Emily Panagiotidou, Christina Rudén, Huan Shu, Christian Lindh, Joelle Ruegg, Chris Gennings Published in: Risk Analysis, 2019, ISSN 0272-4332 Publisher: Blackwell Publishing Inc. DOI: 10.1111/risa.13323 Following Endocrine-Disrupting Effects on Gene Expression in Xenopus laevis Author(s): Petra Spirhanzlova, Michelle Leemans, Barbara A. Demeneix, Jean-Baptiste Fini Published in: Cold Spring Harbor Protocols, Issue 2019/7, 2019, Page(s) pdb.prot098301, ISSN 1559-6095 Publisher: Cold Spring Harbor Laboratory Press DOI: 10.1101/pdb.prot098301 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
