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Comparing the effectiveness and safety of additional low-dose glucocorticoid in treatment strategies for elderly patients with rheumatoid arthritis

Deliverables

Main barriers to implementation of GC use

Main barriers to implementation of GC use

Report on guidelines, regulations and ethical guidance

Report on guidelines regulations and ethical guidance

Report on the educational activities and surveys conducted under GLORIA (2)

Report on the educational activities and surveys conducted under GLORIA

Report and Publication: points to consider for clinical trials in the elderly

Report and Publication points to consider for clinical trials in the elderly

Written scientific documents addressing the limitations of current knowledge

Written scientific documents addressing the limitations of current knowledge

Report on the educational activities and surveys conducted under GLORIA (1)

Report on the educational activities and surveys conducted under GLORIA

Report on analysis of existing guidelines and recommendations

Report: Analysis of existing guidelines and recommendations (international and national in participating countries) regarding the role of GC on the treatment of RA, including survey of patients and prescribers on 1. Acceptability and limitations of current recommendations, 2. Information needed to allow improvement of current recommendations

Report on the educational activities and surveys conducted under GLORIA (3)

Report on the educational activities and surveys conducted under GLORIA

Reports on the progress of GLORIA project at European and American Rheumatology Annual Congresses (2)

Reports on the progress of GLORIA project at European and American Rheumatology Annual Congresses

Report on current status of the involvement of the elderly in clinical trials

Report on current status of the involvement of the elderly in clinical trials

Reports on the progress of GLORIA project at European and American Rheumatology Annual Congresses (1)

Reports on the progress of GLORIA project at European and American Rheumatology Annual Congresses

Scientific content with applicable lay versions made available at website.

Scientific content with applicable lay versions made available at website.

Launch of a web-based survey of patient’s opinions

Launch of a web-based survey of patient’s opinions

Launch of web-based survey

Launch of web-based survey of prescriber’s opinions

Searching for OpenAIRE data...

Publications

Remarkable international variability in reasons for ineligibility and non-participation in the GLORIA trial

Author(s): L Hartman, R Bos, F Buttgereit, M Güler-Yuksel, R Ionescu, MR Kok, WF Lems, M Micaelo, D Opris-Belinski, A Pusztai, EJF Santos, JAP Da Silva, Z Szekanecz, K Zeiner, D Zhang, M Boers
Published in: Scandinavian Journal of Rheumatology, 48/4, 2019, Page(s) 340-341, ISSN 0300-9742
Publisher: Taylor & Francis
DOI: 10.1080/03009742.2018.1559880

The GLORIA adherence subproject: problems and randomization mistakes

Author(s): Linda Hartman, Marc R. Kok, Esmeralda Molenaar, Ed N. Griep, Jaap M. van Laar, Jan Maarten van Woerkom, Cornelia F. Allaart, Hennie G. Raterman, Yvonne P. M. Ruiterman, Marieke J. H. Voshaar, João Redol, Rui M. A. Pinto, L. Thomas Klausch, Willem F. Lems, Maarten Boers
Published in: Journal of Trial and Error, 1, 2021, ISSN 2667-1204
Publisher: University of Utrecht
DOI: 10.36850/e6

Recruitment and Retention of Older People in Clinical Research: A Systematic Literature Review

Author(s): Noah D. Forsat, Andriko Palmowski, Yannick Palmowski, Maarten Boers, Frank Buttgereit
Published in: Journal of the American Geriatrics Society, 2020, ISSN 0002-8614
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/jgs.16875

Association Between Participant Retention and the Proportion of Included Elderly People in Rheumatology Trials: Results From a Series of Exploratory Meta‐Regression Analyses

Author(s): Andriko Palmowski, Sabrina M. Nielsen, Thomas Buttgereit, Yannick Palmowski, Maarten Boers, Robin Christensen, Frank Buttgereit
Published in: Arthritis Care & Research, 72/10, 2020, Page(s) 1490-1496, ISSN 2151-464X
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/acr.24051

Applicability of trials in rheumatoid arthritis and osteoarthritis: A systematic review and meta-analysis of trial populations showing adequate proportion of women, but underrepresentation of elderly people

Author(s): Andriko Palmowski, Thomas Buttgereit, Yannick Palmowski, Sabrina M Nielsen, Maarten Boers, Robin Christensen, Frank Buttgereit
Published in: Seminars in Arthritis and Rheumatism, 48/6, 2019, Page(s) 983-989, ISSN 0049-0172
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.semarthrit.2018.10.017

“Official View” on Glucocorticoids in Rheumatoid Arthritis: A Systematic Review of International Guidelines and Consensus Statements

Author(s): Yannick Palmowski, Thomas Buttgereit, Christian Dejaco, Johannes W. Bijlsma, Eric L. Matteson, Marieke Voshaar, Maarten Boers, Frank Buttgereit
Published in: Arthritis Care & Research, 69/8, 2017, Page(s) 1134-1141, ISSN 2151-464X
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/acr.23185

Outcome measures for adherence data from a medication event monitoring system: A literature review

Author(s): Linda Hartman, Willem F. Lems, Maarten Boers
Published in: Journal of Clinical Pharmacy and Therapeutics, 44/1, 2019, Page(s) 1-5, ISSN 0269-4727
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/jcpt.12757

Harm, benefit and costs associated with low-dose glucocorticoids added to the treatment strategies for rheumatoid arthritis in elderly patients (GLORIA trial): study protocol for a randomised controlled trial.

Author(s): Hartman, L; Rasch, La; Klausch, T; Bijlsma, Hwj; Christensen, R; Smulders, Ym; Ralston, Sh; Buttgereit, F; Cutolo, M; Da Silva JAP,; Opris, D; Rovenský, J; Szamosi, S; Middelink, Lm; Lems, Wf; Boers, M.
Published in: Trials 2018;19:67., 2018, ISSN 1745-6215
Publisher: BioMed Central
DOI: 10.1186/s13063-017-2396-3

Glucocorticoid-trials in rheumatoid arthritis mostly study representative real-world patients: A systematic review and meta-analysis

Author(s): Andriko Palmowski, Sabrina M. Nielsen, Thomas Buttgereit, Yannick Palmowski, Maarten Boers, Robin Christensen, Frank Buttgereit
Published in: Seminars in Arthritis and Rheumatism, 50/6, 2020, Page(s) 1400-1405, ISSN 0049-0172
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.semarthrit.2020.02.016

Patients’ and rheumatologists’ perspectives on the efficacy and safety of low-dose glucocorticoids in rheumatoid arthritis—an international survey within the GLORIA study

Author(s): T Santiago, M Voshaar, M de Wit, P D Carvalho, F Buttgereit, M Cutolo, S   Paolino, G R Castelar Pinheiro, M Boers, J A P Da Silva
Published in: Rheumatology, 60/7, 2021, Page(s) 3334-3342, ISSN 1462-0324
Publisher: Oxford University Press
DOI: 10.1093/rheumatology/keaa785

Barriers and potential solutions in the recruitment and retention of older patients in clinical trials—lessons learned from six large multicentre randomized controlled trials

Author(s): Thomas Buttgereit, Andriko Palmowski, Noah Forsat, Maarten Boers, Miles D Witham, Nicolas Rodondi, Elisavet Moutzouri, Antonio Jesus Quesada Navidad, Arnoud W J van’t Hof, Bart van der Worp, Laura Coll-Planas, Marieke Voshaar, Maarten de Wit, José da Silva, Sven Stegemann, Johannes W Bijlsma, Marcus Koeller, Simon Mooijaart, Patricia M Kearney, Frank Buttgereit
Published in: Age and Ageing, 2021, ISSN 0002-0729
Publisher: Oxford University Press
DOI: 10.1093/ageing/afab147