Comparing the effectiveness and safety of additional low-dose glucocorticoid in treatment strategies for elderly patients with rheumatoid arthritis

Livrables

Main barriers to implementation of GC use
Report on guidelines, regulations and ethical guidance

Report on guidelines regulations and ethical guidance

Report on the educational activities and surveys conducted under GLORIA (2)

Report on the educational activities and surveys conducted under GLORIA

Report and Publication: points to consider for clinical trials in the elderly

Report and Publication points to consider for clinical trials in the elderly

Written scientific documents addressing the limitations of current knowledge
Report on the educational activities and surveys conducted under GLORIA (1)

Report on the educational activities and surveys conducted under GLORIA

Report on analysis of existing guidelines and recommendations

Report: Analysis of existing guidelines and recommendations (international and national in participating countries) regarding the role of GC on the treatment of RA, including survey of patients and prescribers on 1. Acceptability and limitations of current recommendations, 2. Information needed to allow improvement of current recommendations

Report on the educational activities and surveys conducted under GLORIA (3)

Report on the educational activities and surveys conducted under GLORIA

Reports on the progress of GLORIA project at European and American Rheumatology Annual Congresses (2)

Reports on the progress of GLORIA project at European and American Rheumatology Annual Congresses

Report on current status of the involvement of the elderly in clinical trials
Reports on the progress of GLORIA project at European and American Rheumatology Annual Congresses (1)

Reports on the progress of GLORIA project at European and American Rheumatology Annual Congresses

Scientific content with applicable lay versions made available at website.
Launch of a web-based survey of patient’s opinions
Launch of web-based survey

Launch of web-based survey of prescriber’s opinions

Publications

Remarkable international variability in reasons for ineligibility and non-participation in the GLORIA trial

Auteurs: L Hartman, R Bos, F Buttgereit, M Güler-Yuksel, R Ionescu, MR Kok, WF Lems, M Micaelo, D Opris-Belinski, A Pusztai, EJF Santos, JAP Da Silva, Z Szekanecz, K Zeiner, D Zhang, M Boers
Publié dans: Scandinavian Journal of Rheumatology, Numéro 48/4, 2019, Page(s) 340-341, ISSN 0300-9742
Éditeur: Taylor & Francis
DOI: 10.1080/03009742.2018.1559880

The GLORIA adherence subproject: problems and randomization mistakes

Auteurs: Linda Hartman, Marc R. Kok, Esmeralda Molenaar, Ed N. Griep, Jaap M. van Laar, Jan Maarten van Woerkom, Cornelia F. Allaart, Hennie G. Raterman, Yvonne P. M. Ruiterman, Marieke J. H. Voshaar, João Redol, Rui M. A. Pinto, L. Thomas Klausch, Willem F. Lems, Maarten Boers
Publié dans: Journal of Trial and Error, Numéro 1, 2021, ISSN 2667-1204
Éditeur: University of Utrecht
DOI: 10.36850/e6

Recruitment and Retention of Older People in Clinical Research: A Systematic Literature Review

Auteurs: Noah D. Forsat, Andriko Palmowski, Yannick Palmowski, Maarten Boers, Frank Buttgereit
Publié dans: Journal of the American Geriatrics Society, 2020, ISSN 0002-8614
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/jgs.16875

Association Between Participant Retention and the Proportion of Included Elderly People in Rheumatology Trials: Results From a Series of Exploratory Meta‐Regression Analyses

Auteurs: Andriko Palmowski, Sabrina M. Nielsen, Thomas Buttgereit, Yannick Palmowski, Maarten Boers, Robin Christensen, Frank Buttgereit
Publié dans: Arthritis Care & Research, Numéro 72/10, 2020, Page(s) 1490-1496, ISSN 2151-464X
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/acr.24051

Applicability of trials in rheumatoid arthritis and osteoarthritis: A systematic review and meta-analysis of trial populations showing adequate proportion of women, but underrepresentation of elderly people

Auteurs: Andriko Palmowski, Thomas Buttgereit, Yannick Palmowski, Sabrina M Nielsen, Maarten Boers, Robin Christensen, Frank Buttgereit
Publié dans: Seminars in Arthritis and Rheumatism, Numéro 48/6, 2019, Page(s) 983-989, ISSN 0049-0172
Éditeur: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.semarthrit.2018.10.017

“Official View” on Glucocorticoids in Rheumatoid Arthritis: A Systematic Review of International Guidelines and Consensus Statements

Auteurs: Yannick Palmowski, Thomas Buttgereit, Christian Dejaco, Johannes W. Bijlsma, Eric L. Matteson, Marieke Voshaar, Maarten Boers, Frank Buttgereit
Publié dans: Arthritis Care & Research, Numéro 69/8, 2017, Page(s) 1134-1141, ISSN 2151-464X
Éditeur: John Wiley & Sons Inc.
DOI: 10.1002/acr.23185

Outcome measures for adherence data from a medication event monitoring system: A literature review

Auteurs: Linda Hartman, Willem F. Lems, Maarten Boers
Publié dans: Journal of Clinical Pharmacy and Therapeutics, Numéro 44/1, 2019, Page(s) 1-5, ISSN 0269-4727
Éditeur: Blackwell Publishing Inc.
DOI: 10.1111/jcpt.12757

Harm, benefit and costs associated with low-dose glucocorticoids added to the treatment strategies for rheumatoid arthritis in elderly patients (GLORIA trial): study protocol for a randomised controlled trial.

Auteurs: Hartman, L; Rasch, La; Klausch, T; Bijlsma, Hwj; Christensen, R; Smulders, Ym; Ralston, Sh; Buttgereit, F; Cutolo, M; Da Silva JAP,; Opris, D; Rovenský, J; Szamosi, S; Middelink, Lm; Lems, Wf; Boers, M.
Publié dans: Trials 2018;19:67., 2018, ISSN 1745-6215
Éditeur: BioMed Central
DOI: 10.1186/s13063-017-2396-3

Glucocorticoid-trials in rheumatoid arthritis mostly study representative real-world patients: A systematic review and meta-analysis

Auteurs: Andriko Palmowski, Sabrina M. Nielsen, Thomas Buttgereit, Yannick Palmowski, Maarten Boers, Robin Christensen, Frank Buttgereit
Publié dans: Seminars in Arthritis and Rheumatism, Numéro 50/6, 2020, Page(s) 1400-1405, ISSN 0049-0172
Éditeur: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.semarthrit.2020.02.016

Patients’ and rheumatologists’ perspectives on the efficacy and safety of low-dose glucocorticoids in rheumatoid arthritis—an international survey within the GLORIA study

Auteurs: T Santiago, M Voshaar, M de Wit, P D Carvalho, F Buttgereit, M Cutolo, S Paolino, G R Castelar Pinheiro, M Boers, J A P Da Silva
Publié dans: Rheumatology, Numéro 60/7, 2021, Page(s) 3334-3342, ISSN 1462-0324
Éditeur: Oxford University Press
DOI: 10.1093/rheumatology/keaa785

Barriers and potential solutions in the recruitment and retention of older patients in clinical trials—lessons learned from six large multicentre randomized controlled trials

Auteurs: Thomas Buttgereit, Andriko Palmowski, Noah Forsat, Maarten Boers, Miles D Witham, Nicolas Rodondi, Elisavet Moutzouri, Antonio Jesus Quesada Navidad, Arnoud W J van’t Hof, Bart van der Worp, Laura Coll-Planas, Marieke Voshaar, Maarten de Wit, José da Silva, Sven Stegemann, Johannes W Bijlsma, Marcus Koeller, Simon Mooijaart, Patricia M Kearney, Frank Buttgereit
Publié dans: Age and Ageing, 2021, ISSN 0002-0729
Éditeur: Oxford University Press
DOI: 10.1093/ageing/afab147

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