Deliverables Websites, patent fillings, videos etc. (7) Third set of scientific publications three scientific publications in highquality international refereed journals on CARBAZYME results Posts, press releases, news items Coverage of CARBAZYMES activities in social media showcasing IPRcleared information press releases covering CARBAZYMES achievements meetings and workshops and through public presentations during Open Days scientific seminars and lectures to undergraduate or graduate students First set of scientific publications two scientific publications in highquality international refereed journals on CARBAZYME results Fourth set of scientific publications three scientific publications in high-quality international refereed journals on CARBAZYME results Project website Project web site to support project visibility and distribution of information to the public including opportunity for subscription to an enewsletter on specific sections related to every RTD Work Package and report news about events meetings etc Second set of scientific publications two scientific publications in highquality international refereed journals on CARBAZYME results Dissemination and branding standards Dissemination standards and publicity material that contribute to associate a corporate image to CARBAZYMES and thus contribute to branding which contains the following elements Project logo website layout project flyers layout project slides layout enewsletter layout Other (2) Publicity materials Publicity material to promote visibility of ECsupported research activities of CARBAZYMES at public locations and events International Outreach Symposium International Symposium organized (or-co-organized) in the field of biocatalysis for active dissemination of specific CARBAZYME results to stakeholders and technology users in the academic and industrial sectors Publications Peer reviewed articles (21) Cover Picture: Nucleophile Promiscuity of Engineered Class II Pyruvate Aldolase YfaU from E. Coli (Angew. Chem. Int. Ed. 14/2018) Author(s): Karel Hernández, Jesús Joglar, Jordi Bujons, Teodor Parella, Pere Clapés Published in: Angewandte Chemie International Edition, Issue 57/14, 2018, Page(s) 3521-3521, ISSN 1433-7851 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/anie.201802275 Mathematical model of the MenD-catalyzed 1,4-addition (Stetter reaction) of α-ketoglutaric acid to acrylonitrile Author(s): Martina Sudar, Đurđa Vasić-Rački, Michael Müller, Alexandra Walter, Zvjezdana Findrik Blažević Published in: Journal of Biotechnology, Issue 268, 2018, Page(s) 71-80, ISSN 0168-1656 Publisher: Elsevier BV DOI: 10.1016/j.jbiotec.2018.01.013 2-Keto-3-Deoxy- l -Rhamnonate Aldolase (YfaU) as Catalyst in Aldol Additions of Pyruvate to Amino Aldehyde Derivatives Author(s): Karel Hernández, Ariadna Gómez, Jesús Joglar, Jordi Bujons, Teodor Parella, Pere Clapés Published in: Advanced Synthesis & Catalysis, Issue 359/12, 2017, Page(s) 2090-2100, ISSN 1615-4150 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/adsc.201700360 Fluorogenic kinetic assay for high-throughput discovery of stereoselective ketoreductases relevant to pharmaceutical synthesis Author(s): Yen-Chi Thai, Anna Szekrenyi, Yuyin Qi, Gary W. Black, Simon J. Charnock, Wolf-Dieter Fessner Published in: Bioorganic & Medicinal Chemistry, Issue 26/7, 2018, Page(s) 1320-1326, ISSN 0968-0896 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.bmc.2017.05.024 Recent advances on halohydrin dehalogenases—from enzyme identification to novel biocatalytic applications Author(s): Anett Schallmey, Marcus Schallmey Published in: Applied Microbiology and Biotechnology, Issue 100/18, 2016, Page(s) 7827-7839, ISSN 0175-7598 Publisher: Springer Verlag DOI: 10.1007/s00253-016-7750-y The Generation and Exploitation of Protein Mutability Landscapes for Enzyme Engineering Author(s): Jan-Ytzen van der Meer, Lieuwe Biewenga, Gerrit J. Poelarends Published in: ChemBioChem, 2016, ISSN 1439-4227 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/cbic.201600382 Biocatalytic Aldol Addition of Simple Aliphatic Nucleophiles to Hydroxyaldehydes Author(s): Raquel Roldán, Karel Hernandez, Jesús Joglar, Jordi Bujons, Teodor Parella, Israel Sánchez-Moreno, Virgil Hélaine, Marielle Lemaire, Christine Guérard-Hélaine, Wolf-Dieter Fessner, Pere Clapés Published in: ACS Catalysis, Issue 8/9, 2018, Page(s) 8804-8809, ISSN 2155-5435 Publisher: American Chemical Society DOI: 10.1021/acscatal.8b02486 Exploiting distant homologues for phasing through the generation of compact fragments, local fold refinement and partial solution combination. Author(s): Millán, Claudia; Sammito, Massimo; McCoy, Airlie; Nascimento, Andrey F Ziem; Petrillo, Giovanna; Oeffner, Robert; Domínguez-Gil, Teresa; Hermoso, Juan A; Read, Randy; Usón, Isabel Published in: Acta Crystallographica. Section D, Structural Biology, Issue 6, 2018, Page(s) D74, 290–304, ISSN 2059-7983 Publisher: IUCr Journals CRYSTALLOGRAPHY JOURNALS ONLINE DOI: 10.17863/CAM.25122 Aldolase-Catalyzed Asymmetric Synthesis of N-Heterocycles by Addition of Simple Aliphatic Nucleophiles to Aminoaldehydes Author(s): Raquel Roldán, Karel Hernández, Jesús Joglar, Jordi Bujons, Teodor Parella, Wolf-Dieter Fessner, Pere Clapés Published in: Advanced Synthesis & Catalysis, Issue Adv. Synth. Catal., 2019, Page(s) 361, 1–16, ISSN 1615-4150 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/adsc.201801530 Complete Switch of Reaction Specificity of an Aldolase by Directed Evolution In Vitro: Synthesis of Generic Aliphatic Aldol Products Author(s): Sebastian Junker, Raquel Roldan, Henk-Jan Joosten, Pere Clapés, Wolf-Dieter Fessner Published in: Angewandte Chemie International Edition, Issue 57/32, 2018, Page(s) 10153-10157, ISSN 1433-7851 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/anie.201804831 Nucleophile Promiscuity of Engineered Class II Pyruvate Aldolase YfaU from E. Coli Author(s): Karel Hernández, Jesús Joglar, Jordi Bujons, Teodor Parella, Pere Clapés Published in: Angewandte Chemie, Issue 130/14, 2018, Page(s) 3645-3649, ISSN 0044-8249 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/ange.201711289 nanoDSF as screening tool for enzyme libraries and biotechnology development Author(s): Anders O. Magnusson, Anna Szekrenyi, Henk‐Jan Joosten, James Finnigan, Simon Charnock, Wolf‐Dieter Fessner Published in: The FEBS Journal, Issue 286/1, 2018, Page(s) 184-204, ISSN 1742-464X Publisher: Blackwell Publishing Inc. DOI: 10.1111/febs.14696 Application of Chemical Engineering Methodology in Process Development: A Case Study of MenD-catalyzed Synthesis of 6-Cyano-4-oxohexanoic Acid Author(s): M. Sudar Published in: Chemical and Biochemical Engineering Quarterly, Issue 32/4, 2019, Page(s) 501-510, ISSN 0352-9568 Publisher: Hrvatsko Drustvo Kemijskih Inzenjera i Tehnologa/Croatian Society of Chemical Engineers DOI: 10.15255/cabeq.2018.1393 Structural and Mutagenesis Studies of the Thiamine-Dependent, Ketone-Accepting YerE from Pseudomonas protegens Author(s): Sabrina Hampel, Jan-Patrick Steitz, Anna Baierl, Patrizia Lehwald, Luzia Wiesli, Michael Richter, Alexander Fries, Martina Pohl, Gunter Schneider, Doreen Dobritzsch, Michael Müller Published in: ChemBioChem, Issue 19/21, 2018, Page(s) 2283-2292, ISSN 1439-4227 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/cbic.201800325 Enantioselective Synthesis of Pharmaceutically Active γ-Aminobutyric Acids Using a Tailor-Made Artificial Michaelase in One-Pot Cascade Reactions Author(s): Lieuwe Biewenga, Thangavelu Saravanan, Andreas Kunzendorf, Jan-Ytzen van der Meer, Tjaard Pijning, Pieter G. Tepper, Ronald van Merkerk, Simon J. Charnock, Andy-Mark W. H. Thunnissen, Gerrit J. Poelarends Published in: ACS Catalysis, Issue 9/2, 2019, Page(s) 1503-1513, ISSN 2155-5435 Publisher: American Chemical Society DOI: 10.1021/acscatal.8b04299 2‐Deoxyribose‐5‐phosphate aldolase from Thermotoga maritima in the synthesis of a statin side‐chain precursor: characterization, modeling and optimization Author(s): Anera Švarc, Zvjezdana Findrik Blažević, Đurđa Vasić‐Rački, Anna Szekrenyi, Wolf‐Dieter Fessner, Simon J Charnock, Ana Vrsalović Presečki Published in: Journal of Chemical Technology & Biotechnology, Issue 94/6, 2019, Page(s) 1832-1842, ISSN 0268-2575 Publisher: John Wiley & Sons Inc. DOI: 10.1002/jctb.5956 Selective Ring‐Opening of Di‐Substituted Epoxides Catalysed by Halohydrin Dehalogenases Author(s): Elia Calderini, Julia Wessel, Philipp Süss, Patrick Schrepfer, Rainer Wardenga, Anett Schallmey Published in: ChemCatChem, Issue 11/8, 2019, Page(s) 2099-2106, ISSN 1867-3880 Publisher: Wiley - VCH Verlag GmbH & CO. KGaA DOI: 10.1002/cctc.201900103 Biocatalytic Asymmetric Michael Additions of Nitromethane to α,β-Unsaturated Aldehydes via Enzyme-bound Iminium Ion Intermediates Author(s): Chao Guo, Mohammad Saifuddin, Thangavelu Saravanan, Masih Sharifi, Gerrit J. Poelarends Published in: ACS Catalysis, Issue 9/5, 2019, Page(s) 4369-4373, ISSN 2155-5435 Publisher: American Chemical Society DOI: 10.1021/acscatal.9b00780 Alteration of the Route to Menaquinone towards Isochorismate‐Derived Metabolites Author(s): Alexander Fries, Laura S. Mazzaferro, Björn Grüning, Philippe Bisel, Karin Stibal, Patrick C. F. Buchholz, Jürgen Pleiss, Georg A. Sprenger, Michael Müller Published in: ChemBioChem, 2019, ISSN 1439-4227 Publisher: John Wiley & Sons Ltd. DOI: 10.1002/cbic.201900050 Combining Aldolases and Transaminases for the Synthesis of 2-Amino-4-hydroxybutanoic Acid Author(s): Karel Hernandez, Jordi Bujons, Jesús Joglar, Simon J. Charnock, Pablo Domínguez de María, Wolf Dieter Fessner, Pere Clapés Published in: ACS Catalysis, Issue 7/3, 2017, Page(s) 1707-1711, ISSN 2155-5435 Publisher: American Chemical Society DOI: 10.1021/acscatal.6b03181 Are in vivo selections on the path to extinction? Author(s): José Berenguer, Mario Mencía, Aurelio Hidalgo Published in: Microbial Biotechnology, Issue 10/1, 2017, Page(s) 46-49, ISSN 1751-7915 Publisher: John Wiley & Sons, Ltd DOI: 10.1111/1751-7915.12490 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
