Engineering a scaffold based therapy for corneal regeneration

Información del proyecto

EyeRegen

Identificador del acuerdo de subvención: 637460

DOI 10.3030/637460

Proyecto cerrado

Fecha de la firma de la CE 26 Febrero 2015

Fecha de inicio 1 Julio 2015

Fecha de finalización 31 Diciembre 2020

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total € 1 498 734,00

Aportación de la UE € 1 498 734,00

Coordinado por

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Ireland

Publicaciones

Peer reviewed articles (14)

Silk fibroin safety in the eye: a review that highlights a concern

Autores: Peter W Madden, Igor Klyubin, Mark J Ahearne
Publicado en: BMJ Open Ophthalmology, Edición 5/1, 2020, Página(s) e000510, ISSN 2397-3269
Editor: BMJ Journals
DOI: 10.1136/bmjophth-2020-000510

Engineering a Corneal Stromal Equivalent Using a Novel Multilayered Fabrication Assembly Technique

Autores: Julia Fernández-Pérez, Peter W. Madden, Mark Ahearne
Publicado en: Tissue Engineering Part A, Edición 26/19-20, 2020, Página(s) 1030-1041, ISSN 1937-3341
Editor: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tea.2020.0019

Designing Scaffolds for Corneal Regeneration

Autores: Mark Ahearne, Julia Fernández‐Pérez, Sophia Masterton, Peter W. Madden, Promita Bhattacharjee
Publicado en: Advanced Functional Materials, Edición 30/44, 2020, Página(s) 1908996, ISSN 1616-301X
Editor: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.201908996

Effect of substrate topography on the regulation of human corneal stromal cells

Autores: Promita Bhattacharjee, Brenton. L. Cavanagh, Mark Ahearne
Publicado en: Colloids and Surfaces B: Biointerfaces, Edición 190, 2020, Página(s) 110971, ISSN 0927-7765
Editor: Elsevier BV
DOI: 10.1016/j.colsurfb.2020.110971

Fabrication and Biocompatibility of Electroconductive Silk Fibroin/PEDOT: PSS Composites for Corneal Epithelial Regeneration

Autores: Promita Bhattacharjee, Mark Ahearne
Publicado en: Polymers, Edición 12/12, 2020, Página(s) 3028, ISSN 2073-4360
Editor: MDPI
DOI: 10.3390/polym12123028

Influence of micropatterned substrates on keratocyte phenotype

Autores: Promita Bhattacharjee, Brenton L. Cavanagh, Mark Ahearne
Publicado en: Scientific Reports, Edición 10/1, 2020, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-020-62640-5

Mechanobiology of the corneal epithelium

Autores: Sophia Masterton, Mark Ahearne
Publicado en: Experimental Eye Research, Edición 177, 2018, Página(s) 122-129, ISSN 0014-4835
Editor: Academic Press
DOI: 10.1016/j.exer.2018.08.001

Influence of Biochemical Cues in Human Corneal Stromal Cell Phenotype

Autores: Julia Fernández-Pérez, Mark Ahearne
Publicado en: Current Eye Research, Edición 44:2, 135-146, 2018, Página(s) 1-12, ISSN 0271-3683
Editor: Swets & Zeitlinger
DOI: 10.1080/02713683.2018.1536216

Potential for combined delivery of riboflavin and all-trans retinoic acid, from silk fibroin for corneal bioengineering

Autores: Promita Bhattacharjee, Julia Fernández-Pérez, Mark Ahearne
Publicado en: Materials Science and Engineering: C, Edición 105, 2019, Página(s) 110093, ISSN 0928-4931
Editor: Elsevier BV
DOI: 10.1016/j.msec.2019.110093

The impact of decellularization methods on extracellular matrix derived hydrogels

Autores: Julia Fernández-Pérez, Mark Ahearne
Publicado en: Scientific Reports, Edición 9/1, 2019, ISSN 2045-2322
Editor: Nature Publishing Group
DOI: 10.1038/s41598-019-49575-2

Characterization of extracellular matrix modified poly(ε-caprolactone) electrospun scaffolds with differing fiber orientations for corneal stroma regeneration

Autores: Julia Fernández-Pérez, Karl E. Kador, Amy P. Lynch, Mark Ahearne
Publicado en: Materials Science and Engineering: C, Edición 108, 2020, Página(s) 110415, ISSN 0928-4931
Editor: Elsevier BV
DOI: 10.1016/j.msec.2019.110415

Influence of polydimethylsiloxane substrate stiffness on corneal epithelial cells

Autores: Sophia Masterton, Mark Ahearne
Publicado en: Royal Society Open Science, Edición 6/12, 2019, Página(s) 191796, ISSN 2054-5703
Editor: Royal Society
DOI: 10.1098/rsos.191796

The Effect of Calcium and Glucose Concentration on Corneal Epithelial Cell Lines Differentiation, Proliferation, and Focal Adhesion Expression

Autores: Sophia Masterton, Mark Ahearne
Publicado en: BioResearch Open Access, Edición 8/1, 2019, Página(s) 74-83, ISSN 2164-7860
Editor: Mary Ann Liebert
DOI: 10.1089/biores.2018.0036

Significance of Crosslinking Approaches in the Development of Next Generation Hydrogels for Corneal Tissue Engineering

Autores: Promita Bhattacharjee, Mark Ahearne
Publicado en: Pharmaceutics, Edición 13/3, 2021, Página(s) 319, ISSN 1999-4923
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13030319