Engineering a scaffold based therapy for corneal regeneration

Informazioni relative al progetto

EyeRegen

ID dell’accordo di sovvenzione: 637460

DOI 10.3030/637460

Progetto chiuso

Data della firma CE 26 Febbraio 2015

Data di avvio 1 Luglio 2015

Data di completamento 31 Dicembre 2020

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 498 734,00

Contributo UE € 1 498 734,00

Coordinato da

THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
Ireland

Pubblicazioni

Peer reviewed articles (14)

Silk fibroin safety in the eye: a review that highlights a concern

Autori: Peter W Madden, Igor Klyubin, Mark J Ahearne
Pubblicato in: BMJ Open Ophthalmology, Numero 5/1, 2020, Pagina/e e000510, ISSN 2397-3269
Editore: BMJ Journals
DOI: 10.1136/bmjophth-2020-000510

Engineering a Corneal Stromal Equivalent Using a Novel Multilayered Fabrication Assembly Technique

Autori: Julia Fernández-Pérez, Peter W. Madden, Mark Ahearne
Pubblicato in: Tissue Engineering Part A, Numero 26/19-20, 2020, Pagina/e 1030-1041, ISSN 1937-3341
Editore: Mary Ann Liebert Inc.
DOI: 10.1089/ten.tea.2020.0019

Designing Scaffolds for Corneal Regeneration

Autori: Mark Ahearne, Julia Fernández‐Pérez, Sophia Masterton, Peter W. Madden, Promita Bhattacharjee
Pubblicato in: Advanced Functional Materials, Numero 30/44, 2020, Pagina/e 1908996, ISSN 1616-301X
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/adfm.201908996

Effect of substrate topography on the regulation of human corneal stromal cells

Autori: Promita Bhattacharjee, Brenton. L. Cavanagh, Mark Ahearne
Pubblicato in: Colloids and Surfaces B: Biointerfaces, Numero 190, 2020, Pagina/e 110971, ISSN 0927-7765
Editore: Elsevier BV
DOI: 10.1016/j.colsurfb.2020.110971

Fabrication and Biocompatibility of Electroconductive Silk Fibroin/PEDOT: PSS Composites for Corneal Epithelial Regeneration

Autori: Promita Bhattacharjee, Mark Ahearne
Pubblicato in: Polymers, Numero 12/12, 2020, Pagina/e 3028, ISSN 2073-4360
Editore: MDPI
DOI: 10.3390/polym12123028

Influence of micropatterned substrates on keratocyte phenotype

Autori: Promita Bhattacharjee, Brenton L. Cavanagh, Mark Ahearne
Pubblicato in: Scientific Reports, Numero 10/1, 2020, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-020-62640-5

Mechanobiology of the corneal epithelium

Autori: Sophia Masterton, Mark Ahearne
Pubblicato in: Experimental Eye Research, Numero 177, 2018, Pagina/e 122-129, ISSN 0014-4835
Editore: Academic Press
DOI: 10.1016/j.exer.2018.08.001

Influence of Biochemical Cues in Human Corneal Stromal Cell Phenotype

Autori: Julia Fernández-Pérez, Mark Ahearne
Pubblicato in: Current Eye Research, Numero 44:2, 135-146, 2018, Pagina/e 1-12, ISSN 0271-3683
Editore: Swets & Zeitlinger
DOI: 10.1080/02713683.2018.1536216

Potential for combined delivery of riboflavin and all-trans retinoic acid, from silk fibroin for corneal bioengineering

Autori: Promita Bhattacharjee, Julia Fernández-Pérez, Mark Ahearne
Pubblicato in: Materials Science and Engineering: C, Numero 105, 2019, Pagina/e 110093, ISSN 0928-4931
Editore: Elsevier BV
DOI: 10.1016/j.msec.2019.110093

The impact of decellularization methods on extracellular matrix derived hydrogels

Autori: Julia Fernández-Pérez, Mark Ahearne
Pubblicato in: Scientific Reports, Numero 9/1, 2019, ISSN 2045-2322
Editore: Nature Publishing Group
DOI: 10.1038/s41598-019-49575-2

Characterization of extracellular matrix modified poly(ε-caprolactone) electrospun scaffolds with differing fiber orientations for corneal stroma regeneration

Autori: Julia Fernández-Pérez, Karl E. Kador, Amy P. Lynch, Mark Ahearne
Pubblicato in: Materials Science and Engineering: C, Numero 108, 2020, Pagina/e 110415, ISSN 0928-4931
Editore: Elsevier BV
DOI: 10.1016/j.msec.2019.110415

Influence of polydimethylsiloxane substrate stiffness on corneal epithelial cells

Autori: Sophia Masterton, Mark Ahearne
Pubblicato in: Royal Society Open Science, Numero 6/12, 2019, Pagina/e 191796, ISSN 2054-5703
Editore: Royal Society
DOI: 10.1098/rsos.191796

The Effect of Calcium and Glucose Concentration on Corneal Epithelial Cell Lines Differentiation, Proliferation, and Focal Adhesion Expression

Autori: Sophia Masterton, Mark Ahearne
Pubblicato in: BioResearch Open Access, Numero 8/1, 2019, Pagina/e 74-83, ISSN 2164-7860
Editore: Mary Ann Liebert
DOI: 10.1089/biores.2018.0036

Significance of Crosslinking Approaches in the Development of Next Generation Hydrogels for Corneal Tissue Engineering

Autori: Promita Bhattacharjee, Mark Ahearne
Pubblicato in: Pharmaceutics, Numero 13/3, 2021, Pagina/e 319, ISSN 1999-4923
Editore: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13030319