Objective
HIV-1 is one of the most genetically variable human pathogens. Given this extremely high evolutionary rate of the virus, we can trace the recent spread of the HIV-1 epidemic using molecular data. Phylogenetic analyses have been used in monitoring the molec ular epidemiology of HIV-1 at a global scale, within single countries and risk groups, or for the investigation of the HIV-1 transmission in several cases of uncertain histories. The accuracy of different phylogenetic methods, to truly reconstruct HIV-1 ep idemiological relationships, has been previously investigated by analyzing DNA sequences from patients, for which the transmission events and dates were accurately known. (HIV-1 Swedish transmission chain) Although analyses of DNA sequences isolated from p atients infected from a single source (transmission chains) provide valuable information about the evolution of the virus after sequential transmissions, as well as about the levels of concordance between the evolutionary tree and the transmission tree; th ey don¿t provide evidence about the ability of different phylogenetic methods to truly reconstruct potential clusters of epidemiologically closely linked patients within a population. It is our objective to address the latter question, by analyzing HIV-1 s equences isolated from individuals, for which the close epidemiological link has been independently documented, including also sequences from diverse origin; thus searching for the optimal methodology for HIV-1 contact tracing. Moreover, we will perform a molecular epidemiology study of HIV-1 infection in Greece; investigating how the epidemic spreads among and within different transmission risk groups, and inferring the intermixing (migration) rates of viral infection between the Greek residents and immigr ants or contacts from Africa, Europe, or other geographic areas, and vice versa.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- humanities history and archaeology history
- natural sciences biological sciences microbiology virology
- natural sciences biological sciences genetics DNA
- medical and health sciences health sciences public health epidemiology
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
FP6-2002-MOBILITY-11
See other projects for this call
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Coordinator
ATHENS
Greece
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.