Injectable anisotropic microgel-in-hydrogel matrices for spinal cord repair

Project Information

ANISOGEL

Grant agreement ID: 637853

DOI

10.3030/637853

Project closed

EC signature date 13 February 2015

Start date 1 March 2015

End date 31 August 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 435 396,00

EU contribution

€ 1 435 396,00

Coordinated by

DWI LEIBNIZ-INSTITUT FUR INTERAKTIVE MATERIALIEN EV
Germany

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (15)

Granular Cellulose Nanofibril Hydrogel Scaffolds for 3D Cell Cultivation

Author(s): David B. Gehlen, Niklas Jürgens, Abdolrahman Omidinia‐Anarkoli, Tamás Haraszti, Julian George, Andreas Walther, Hua Ye, Laura De Laporte
Published in: Macromolecular Rapid Communications, Issue 41/18, 2020, Page(s) 2000191, ISSN 1022-1336
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/marc.202000191

Bicyclic RGD peptides enhance nerve growth in synthetic PEG-based Anisogels

Author(s): Sitara Vedaraman, Dominik Bernhagen, Tamas Haraszti, Christopher Licht, Arturo Castro Nava, Abdolrahman Omidinia Anarkoli, Peter Timmerman, Laura De Laporte
Published in: Biomaterials Science, Issue 9/12, 2021, Page(s) 4329-4342, ISSN 2047-4830
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0bm02051f

Predicting the orientation of magnetic microgel rods for soft anisotropic biomimetic hydrogels

Author(s): Jonas C. Rose, Maaike Fölster, Lukas Kivilip, Jose L. Gerardo-Nava, Esther E. Jaekel, David B. Gehlen, Wilko Rohlfs, Laura De Laporte
Published in: Polymer Chemistry, Issue 11/2, 2020, Page(s) 496-507, ISSN 1759-9954
Publisher: Royal Society of Chemistry
DOI: 10.1039/c9py01008d

How Much Physical Guidance is Needed to Orient Growing Axons in 3D Hydrogels?

Author(s): Jonas C. Rose, David B. Gehlen, Abdolrahman Omidinia‐Anarkoli, Maaike Fölster, Tamás Haraszti, Esther E. Jaekel, Laura De Laporte
Published in: Advanced Healthcare Materials, Issue 9/21, 2020, Page(s) 2000886, ISSN 2192-2640
Publisher: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202000886

Compartmentalized Jet Polymerization as a High‐Resolution Process to Continuously Produce Anisometric Microgel Rods with Adjustable Size and Stiffness

Author(s): Andreas J. D. Krüger, Onur Bakirman, Luis. P. B. Guerzoni, Alexander Jans, David B. Gehlen, Dirk Rommel, Tamás Haraszti, Alexander J. C. Kuehne, Laura De Laporte
Published in: Advanced Materials, Issue 31/49, 2019, Page(s) 1903668, ISSN 0935-9648
Publisher: United Nations Industrial Developement Organization
DOI: 10.1002/adma.201903668

Anisometric Microstructures to Determine Minimal Critical Physical Cues Required for Neurite Alignment

Author(s): Sitara Vedaraman, Amaury Perez‐Tirado, Tamas Haraszti, Jose Gerardo‐Nava, Akihiro Nishiguchi, Laura De Laporte
Published in: Advanced Healthcare Materials, Issue 10/20, 2021, Page(s) 2100874, ISSN 2192-2640
Publisher: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202100874

Biofunctionalized aligned microgels provide 3D cell guidance to mimic complex tissue matrices

Author(s): Jonas C. Rose, David B. Gehlen, Tamás Haraszti, Jens Köhler, Christopher J. Licht, Laura De Laporte
Published in: Biomaterials, Issue 163, 2018, Page(s) 128-141, ISSN 0142-9612
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2018.02.001

Solvent-Induced Nanotopographies of Single Microfibers Regulate Cell Mechanotransduction

Author(s): Abdolrahman Omidinia-Anarkoli, Rahul Rimal, Yashoda Chandorkar, David B. Gehlen, Jonas C. Rose, Khosrow Rahimi, Tamás Haraszti, Laura De Laporte
Published in: ACS Applied Materials & Interfaces, Issue 11/8, 2019, Page(s) 7671-7685, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.8b17955

A catalyst-free, temperature controlled gelation system for in-mold fabrication of microgels

Author(s): Andreas J. D. Krüger, Jens Köhler, Stefan Cichosz, Jonas C. Rose, David B. Gehlen, Tamás Haraszti, Martin Möller, Laura De Laporte
Published in: Chemical Communications, Issue 54/50, 2018, Page(s) 6943-6946, ISSN 1359-7345
Publisher: Royal Society of Chemistry
DOI: 10.1039/c8cc02478b

Hierarchical Design of Tissue Regenerative Constructs

Author(s): Jonas C. Rose, Laura De Laporte
Published in: Advanced Healthcare Materials, Issue 7/6, 2018, Page(s) 1701067, ISSN 2192-2640
Publisher: John Wiley and Sons Ltd
DOI: 10.1002/adhm.201701067

Nerve Cells Decide to Orient inside an Injectable Hydrogel with Minimal Structural Guidance

Author(s): Jonas C. Rose, María Cámara-Torres, Khosrow Rahimi, Jens Köhler, Martin Möller, Laura De Laporte
Published in: Nano Letters, Issue 17/6, 2017, Page(s) 3782-3791, ISSN 1530-6984
Publisher: American Chemical Society
DOI: 10.1021/acs.nanolett.7b01123

An Injectable Hybrid Hydrogel with Oriented Short Fibers Induces Unidirectional Growth of Functional Nerve Cells

Author(s): Abdolrahman Omidinia-Anarkoli, Sarah Boesveld, Urandelger Tuvshindorj, Jonas C. Rose, Tamás Haraszti, Laura De Laporte
Published in: Small, Issue 13/36, 2017, Page(s) 1702207, ISSN 1613-6810
Publisher: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.201702207

Synthetic 3D PEG-Anisogel Tailored with Fibronectin Fragments Induce Aligned Nerve Extension

Author(s): Christopher Licht, Jonas C. Rose, Abdolrahman Omidinia Anarkoli, Delphine Blondel, Marta Roccio, Tamás Haraszti, David B. Gehlen, Jeffrey A. Hubbell, Matthias P. Lutolf, Laura De Laporte
Published in: Biomacromolecules, Issue 20/11, 2019, Page(s) 4075-4087, ISSN 1525-7797
Publisher: American Chemical Society
DOI: 10.1021/acs.biomac.9b00891

Hierarchical fibrous guiding cues at different scales influence linear neurite extension

Author(s): Abdolrahman Omidinia-Anarkoli, John Wesley Ephraim, Rahul Rimal, Laura De Laporte
Published in: Acta Biomaterialia, Issue 113, 2020, Page(s) 350-359, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2020.07.014

Controlling Structure with Injectable Biomaterials to Better Mimic Tissue Heterogeneity and Anisotropy

Author(s): Susan Babu, Filippo Albertino, Abdolrahman Omidinia Anarkoli, Laura De Laporte
Published in: Advanced Healthcare Materials, Issue 10/11, 2021, Page(s) 2002221, ISSN 2192-2640
Publisher: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202002221

Book chapters (1)

Nanofibers and Nanostructured Scaffolds for Nervous System Lesions

Author(s): Jose L. Gerardo Nava, Jonas C. Rose, Haktan Altinova, Paul D. Dalton, Laura De Laporte, Gary A. Brook
Published in: Nanomedicines for Brain Drug Delivery, Issue 157, 2021, Page(s) 61-101, ISBN 978-1-0716-0837-1
Publisher: Springer US
DOI: 10.1007/978-1-0716-0838-8_3

Intellectual Property Rights

Patent (2)

MACROSCOPICALLY ALIGNABLE, INJECTABLE, SOFT HYDROGEL COMPOSITION

Application/Publication number: 16 002078
Date: 2016-09-26
Applicant(s): DWI LEIBNIZ-INSTITUT FUR INTERAKTIVE MATERIALIEN EV

MACROSCOPICALLY ALIGNABLE, INJECTABLE, SOFT HYDROGEL COMPOSITION

Application/Publication number: 17 784168
Date: 2017-09-25
Applicant(s): DWI LEIBNIZ-INSTITUT FUR INTERAKTIVE MATERIALIEN EV