Injectable anisotropic microgel-in-hydrogel matrices for spinal cord repair

Informazioni relative al progetto

ANISOGEL

ID dell’accordo di sovvenzione: 637853

DOI 10.3030/637853

Progetto chiuso

Data della firma CE 13 Febbraio 2015

Data di avvio 1 Marzo 2015

Data di completamento 31 Agosto 2021

Finanziato da

• EXCELLENT SCIENCE - European Research Council (ERC)

Costo totale € 1 435 396,00

Contributo UE € 1 435 396,00

Coordinato da

DWI LEIBNIZ-INSTITUT FUR INTERAKTIVE MATERIALIEN EV
Germany

Pubblicazioni

Peer reviewed articles (15)

Granular Cellulose Nanofibril Hydrogel Scaffolds for 3D Cell Cultivation

Autori: David B. Gehlen, Niklas Jürgens, Abdolrahman Omidinia‐Anarkoli, Tamás Haraszti, Julian George, Andreas Walther, Hua Ye, Laura De Laporte
Pubblicato in: Macromolecular Rapid Communications, Numero 41/18, 2020, Pagina/e 2000191, ISSN 1022-1336
Editore: John Wiley & Sons Ltd.
DOI: 10.1002/marc.202000191

Bicyclic RGD peptides enhance nerve growth in synthetic PEG-based Anisogels

Autori: Sitara Vedaraman, Dominik Bernhagen, Tamas Haraszti, Christopher Licht, Arturo Castro Nava, Abdolrahman Omidinia Anarkoli, Peter Timmerman, Laura De Laporte
Pubblicato in: Biomaterials Science, Numero 9/12, 2021, Pagina/e 4329-4342, ISSN 2047-4830
Editore: Royal Society of Chemistry
DOI: 10.1039/d0bm02051f

Predicting the orientation of magnetic microgel rods for soft anisotropic biomimetic hydrogels

Autori: Jonas C. Rose, Maaike Fölster, Lukas Kivilip, Jose L. Gerardo-Nava, Esther E. Jaekel, David B. Gehlen, Wilko Rohlfs, Laura De Laporte
Pubblicato in: Polymer Chemistry, Numero 11/2, 2020, Pagina/e 496-507, ISSN 1759-9954
Editore: Royal Society of Chemistry
DOI: 10.1039/c9py01008d

How Much Physical Guidance is Needed to Orient Growing Axons in 3D Hydrogels?

Autori: Jonas C. Rose, David B. Gehlen, Abdolrahman Omidinia‐Anarkoli, Maaike Fölster, Tamás Haraszti, Esther E. Jaekel, Laura De Laporte
Pubblicato in: Advanced Healthcare Materials, Numero 9/21, 2020, Pagina/e 2000886, ISSN 2192-2640
Editore: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202000886

Compartmentalized Jet Polymerization as a High‐Resolution Process to Continuously Produce Anisometric Microgel Rods with Adjustable Size and Stiffness

Autori: Andreas J. D. Krüger, Onur Bakirman, Luis. P. B. Guerzoni, Alexander Jans, David B. Gehlen, Dirk Rommel, Tamás Haraszti, Alexander J. C. Kuehne, Laura De Laporte
Pubblicato in: Advanced Materials, Numero 31/49, 2019, Pagina/e 1903668, ISSN 0935-9648
Editore: United Nations Industrial Developement Organization
DOI: 10.1002/adma.201903668

Anisometric Microstructures to Determine Minimal Critical Physical Cues Required for Neurite Alignment

Autori: Sitara Vedaraman, Amaury Perez‐Tirado, Tamas Haraszti, Jose Gerardo‐Nava, Akihiro Nishiguchi, Laura De Laporte
Pubblicato in: Advanced Healthcare Materials, Numero 10/20, 2021, Pagina/e 2100874, ISSN 2192-2640
Editore: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202100874

Biofunctionalized aligned microgels provide 3D cell guidance to mimic complex tissue matrices

Autori: Jonas C. Rose, David B. Gehlen, Tamás Haraszti, Jens Köhler, Christopher J. Licht, Laura De Laporte
Pubblicato in: Biomaterials, Numero 163, 2018, Pagina/e 128-141, ISSN 0142-9612
Editore: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2018.02.001

Solvent-Induced Nanotopographies of Single Microfibers Regulate Cell Mechanotransduction

Autori: Abdolrahman Omidinia-Anarkoli, Rahul Rimal, Yashoda Chandorkar, David B. Gehlen, Jonas C. Rose, Khosrow Rahimi, Tamás Haraszti, Laura De Laporte
Pubblicato in: ACS Applied Materials & Interfaces, Numero 11/8, 2019, Pagina/e 7671-7685, ISSN 1944-8244
Editore: American Chemical Society
DOI: 10.1021/acsami.8b17955

A catalyst-free, temperature controlled gelation system for in-mold fabrication of microgels

Autori: Andreas J. D. Krüger, Jens Köhler, Stefan Cichosz, Jonas C. Rose, David B. Gehlen, Tamás Haraszti, Martin Möller, Laura De Laporte
Pubblicato in: Chemical Communications, Numero 54/50, 2018, Pagina/e 6943-6946, ISSN 1359-7345
Editore: Royal Society of Chemistry
DOI: 10.1039/c8cc02478b

Hierarchical Design of Tissue Regenerative Constructs

Autori: Jonas C. Rose, Laura De Laporte
Pubblicato in: Advanced Healthcare Materials, Numero 7/6, 2018, Pagina/e 1701067, ISSN 2192-2640
Editore: John Wiley and Sons Ltd
DOI: 10.1002/adhm.201701067

Nerve Cells Decide to Orient inside an Injectable Hydrogel with Minimal Structural Guidance

Autori: Jonas C. Rose, María Cámara-Torres, Khosrow Rahimi, Jens Köhler, Martin Möller, Laura De Laporte
Pubblicato in: Nano Letters, Numero 17/6, 2017, Pagina/e 3782-3791, ISSN 1530-6984
Editore: American Chemical Society
DOI: 10.1021/acs.nanolett.7b01123

An Injectable Hybrid Hydrogel with Oriented Short Fibers Induces Unidirectional Growth of Functional Nerve Cells

Autori: Abdolrahman Omidinia-Anarkoli, Sarah Boesveld, Urandelger Tuvshindorj, Jonas C. Rose, Tamás Haraszti, Laura De Laporte
Pubblicato in: Small, Numero 13/36, 2017, Pagina/e 1702207, ISSN 1613-6810
Editore: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.201702207

Synthetic 3D PEG-Anisogel Tailored with Fibronectin Fragments Induce Aligned Nerve Extension

Autori: Christopher Licht, Jonas C. Rose, Abdolrahman Omidinia Anarkoli, Delphine Blondel, Marta Roccio, Tamás Haraszti, David B. Gehlen, Jeffrey A. Hubbell, Matthias P. Lutolf, Laura De Laporte
Pubblicato in: Biomacromolecules, Numero 20/11, 2019, Pagina/e 4075-4087, ISSN 1525-7797
Editore: American Chemical Society
DOI: 10.1021/acs.biomac.9b00891

Hierarchical fibrous guiding cues at different scales influence linear neurite extension

Autori: Abdolrahman Omidinia-Anarkoli, John Wesley Ephraim, Rahul Rimal, Laura De Laporte
Pubblicato in: Acta Biomaterialia, Numero 113, 2020, Pagina/e 350-359, ISSN 1742-7061
Editore: Elsevier BV
DOI: 10.1016/j.actbio.2020.07.014

Controlling Structure with Injectable Biomaterials to Better Mimic Tissue Heterogeneity and Anisotropy

Autori: Susan Babu, Filippo Albertino, Abdolrahman Omidinia Anarkoli, Laura De Laporte
Pubblicato in: Advanced Healthcare Materials, Numero 10/11, 2021, Pagina/e 2002221, ISSN 2192-2640
Editore: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202002221

Book chapters (1)

Nanofibers and Nanostructured Scaffolds for Nervous System Lesions

Autori: Jose L. Gerardo Nava, Jonas C. Rose, Haktan Altinova, Paul D. Dalton, Laura De Laporte, Gary A. Brook
Pubblicato in: Nanomedicines for Brain Drug Delivery, Numero 157, 2021, Pagina/e 61-101, ISBN 978-1-0716-0837-1
Editore: Springer US
DOI: 10.1007/978-1-0716-0838-8_3

Diritti di proprietà intellettuale

Patent (2)

MACROSCOPICALLY ALIGNABLE, INJECTABLE, SOFT HYDROGEL COMPOSITION

Numero candidatura/pubblicazione: 16 002078
Data: 2016-09-26

MACROSCOPICALLY ALIGNABLE, INJECTABLE, SOFT HYDROGEL COMPOSITION

Numero candidatura/pubblicazione: 17 784168
Data: 2017-09-25