Non-coding RNA in Vascular Ageing

Project Information

NOVA

Grant agreement ID: 638178

DOI 10.3030/638178

Project closed

EC signature date 4 March 2015

Start date 1 April 2015

End date 31 March 2021

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 499 693,71

EU contribution € 1 499 693,71

Coordinated by

JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN
Germany

Publications

Peer reviewed articles (8)

Long Non-coding RNA Aerrie Controls DNA Damage Repair via YBX1 to Maintain Endothelial Cell Function

Author(s): Tan Phát Pham, Diewertje I. Bink, Laura Stanicek, Anke van Bergen, Esmee van Leeuwen, Yvonne Tran, Ljubica Matic, Ulf Hedin, Ilka Wittig, Stefanie Dimmeler, Reinier A. Boon
Published in: Frontiers in Cell and Developmental Biology, Issue 8, 2021, ISSN 2296-634X
Publisher: Frontiers Media SA
DOI: 10.3389/fcell.2020.619079

Long non-coding RNA LASSIE regulates shear stress sensing and endothelial barrier function

Author(s): Laura Stanicek, Noelia Lozano-Vidal, Diewertje Ilse Bink, Aukie Hooglugt, Wenjie Yao, Ilka Wittig, Jos van Rijssel, Jaap Diederik van Buul, Anke van Bergen, Alina Klems, Anne Sophie Ramms, Ferdinand Le Noble, Patrick Hofmann, Robert Szulcek, ShengPeng Wang, Stefan Offermanns, Meryem Seda Ercanoglu, Hyouk-Bum Kwon, Didier Stainier, Stephan Huveneers, Leo Kurian, Stefanie Dimmeler, Reinier Abraham B
Published in: Communications Biology, Issue 3/1, 2020, ISSN 2399-3642
Publisher: Nature publishing group
DOI: 10.1038/s42003-020-0987-0

Long Noncoding RNA Meg3 Controls Endothelial Cell Aging and Function

Author(s): Reinier A. Boon, Patrick Hofmann, Katharina M. Michalik, Noelia Lozano-Vidal, Denise Berghäuser, Ariane Fischer, Andrea Knau, Nicolas Jaé, Christoph Schürmann, Stefanie Dimmeler
Published in: Journal of the American College of Cardiology, Issue 68/23, 2016, Page(s) 2589-2591, ISSN 0735-1097
Publisher: Elsevier BV
DOI: 10.1016/j.jacc.2016.09.949

Long Noncoding RNAs

Author(s): Reinier A. Boon, Nicolas Jaé, Lesca Holdt, Stefanie Dimmeler
Published in: Journal of the American College of Cardiology, Issue 67/10, 2016, Page(s) 1214-1226, ISSN 0735-1097
Publisher: Elsevier BV
DOI: 10.1016/j.jacc.2015.12.051

Long non-coding RNA H19 regulates endothelial cell aging via inhibition of STAT3 signalling

Author(s): Patrick Hofmann, Janina Sommer, Kosta Theodorou, Luisa Kirchhof, Ariane Fischer, Yuhuang Li, Ljubica Perisic, Ulf Hedin, Lars Maegdefessel, Stefanie Dimmeler, Reinier A Boon
Published in: Cardiovascular Research, Issue 115/1, 2018, Page(s) 230-242, ISSN 0008-6363
Publisher: Elsevier BV
DOI: 10.1093/cvr/cvy206

Endothelial Cell Metabolism in Atherosclerosis

Author(s): Kosta Theodorou, Reinier A. Boon
Published in: Frontiers in Cell and Developmental Biology, Issue 6, 2018, ISSN 2296-634X
Publisher: Frontiers Media SA
DOI: 10.3389/fcell.2018.00082

The lncRNA GATA6-AS epigenetically regulates endothelial gene expression via interaction with LOXL2

Author(s): Philipp Neumann, Nicolas Jaé, Andrea Knau, Simone F. Glaser, Youssef Fouani, Oliver Rossbach, Marcus Krüger, David John, Albrecht Bindereif, Phillip Grote, Reinier A. Boon, Stefanie Dimmeler
Published in: Nature Communications, Issue 9/1, 2018, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-017-02431-1

Aging-regulated anti-apoptotic long non-coding RNA Sarrah augments recovery from acute myocardial infarction

Author(s): D. Julia Trembinski, Diewertje I. Bink, Kosta Theodorou, Janina Sommer, Ariane Fischer, Anke van Bergen, Chao-Chung Kuo, Ivan G. Costa, Christoph Schürmann, Matthias S. Leisegang, Ralf P. Brandes, Tijna Alekseeva, Boris Brill, Astrid Wietelmann, Christopher N. Johnson, Alexander Spring-Connell, Manuel Kaulich, Stanislas Werfel, Stefan Engelhardt, Marc N. Hirt, Kaja Yorgan, Thomas Eschenhagen, Lui
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-15995-2

Intellectual Property Rights

Patent (3)

Long non-coding RNA for the treatment of diseases associated with endothelial dysfunction

Application/Publication number: EP 15153717
Date: 2015-02-03

Long non-coding RNA for the treatment of diseases associated with endothelial dysfunction

Application/Publication number: EP 15153717
Date: 2015-02-03
Applicant(s): JOHANN WOLFGANG GOETHE-UNIVERSITAET FRANKFURT AM MAIN

Long non-coding RNA for the treatment of diseases associated with endothelial dysfunction

Application/Publication number: EP 15153717
Date: 2015-02-03