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Antibody-Mediated Therapy of HIV-1 Infection

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Combination therapy with anti-HIV-1 antibodies maintains viral suppression

Author(s): Pilar Mendoza, Henning Gruell, Lilian Nogueira, Joy A. Pai, Allison L. Butler, Katrina Millard, Clara Lehmann, Isabelle Suárez, Thiago Y. Oliveira, Julio C. C. Lorenzi, Yehuda Z. Cohen, Christoph Wyen, Tim Kümmerle, Theodora Karagounis, Ching-Lan Lu, Lisa Handl, Cecilia Unson-O’Brien, Roshni Patel, Carola Ruping, Maike Schlotz, Maggi Witmer-Pack, Irina Shimeliovich, Gisela Kremer, Eleonore Tho
Published in: Nature, Issue 561/7724, 2018, Page(s) 479-484, ISSN 0028-0836
DOI: 10.1038/s41586-018-0531-2

Antibody-mediated prevention and treatment of HIV-1 infection

Author(s): Henning Gruell, Florian Klein
Published in: Retrovirology, Issue 15/1, 2018, ISSN 1742-4690
DOI: 10.1186/s12977-018-0455-9

Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals

Author(s): Yotam Bar-On, Henning Gruell, Till Schoofs, Joy A. Pai, Lilian Nogueira, Allison L. Butler, Katrina Millard, Clara Lehmann, Isabelle Suárez, Thiago Y. Oliveira, Theodora Karagounis, Yehuda Z. Cohen, Christoph Wyen, Stefan Scholten, Lisa Handl, Shiraz Belblidia, Juan P. Dizon, Jörg J. Vehreschild, Maggi Witmer-Pack, Irina Shimeliovich, Kanika Jain, Kerstin Fiddike, Kelly E. Seaton, Nicole L. Yate
Published in: Nature Medicine, Issue 24/11, 2018, Page(s) 1701-1707, ISSN 1078-8956
DOI: 10.1038/s41591-018-0186-4

Broadly neutralizing anti-HIV-1 monoclonal antibodies in the clinic

Author(s): Marina Caskey, Florian Klein, Michel C. Nussenzweig
Published in: Nature Medicine, Issue 25/4, 2019, Page(s) 547-553, ISSN 1078-8956
DOI: 10.1038/s41591-019-0412-8

Relationship between intact HIV-1 proviruses in circulating CD4 + T cells and rebound viruses emerging during treatment interruption

Author(s): Ching-Lan Lu, Joy A. Pai, Lilian Nogueira, Pilar Mendoza, Henning Gruell, Thiago Y. Oliveira, John Barton, Julio C. C. Lorenzi, Yehuda Z. Cohen, Lillian B. Cohn, Florian Klein, Marina Caskey, Michel C. Nussenzweig, Mila Jankovic
Published in: Proceedings of the National Academy of Sciences, Issue 115/48, 2018, Page(s) E11341-E11348, ISSN 0027-8424
DOI: 10.1073/pnas.1813512115

HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1

Author(s): T. Schoofs, F. Klein, M. Braunschweig, E. F. Kreider, A. Feldmann, L. Nogueira, T. Oliveira, J. C. C. Lorenzi, E. H. Parrish, G. H. Learn, A. P. West, P. J. Bjorkman, S. J. Schlesinger, M. S. Seaman, J. Czartoski, M. J. McElrath, N. Pfeifer, B. H. Hahn, M. Caskey, M. C. Nussenzweig
Published in: Science, Issue 352/6288, 2016, Page(s) 997-1001, ISSN 0036-8075
DOI: 10.1126/science.aaf0972

Antibody 10-1074 suppresses viremia in HIV-1-infected individuals

Author(s): Marina Caskey, Till Schoofs, Henning Gruell, Allison Settler, Theodora Karagounis, Edward F Kreider, Ben Murrell, Nico Pfeifer, Lilian Nogueira, Thiago Y Oliveira, Gerald H Learn, Yehuda Z Cohen, Clara Lehmann, Daniel Gillor, Irina Shimeliovich, Cecilia Unson-O'Brien, Daniela Weiland, Alexander Robles, Tim Kümmerle, Christoph Wyen, Rebeka Levin, Maggi Witmer-Pack, Kemal Eren, Caroline Ignacio, Sz
Published in: Nature Medicine, Issue 23/2, 2017, Page(s) 185-191, ISSN 1078-8956
DOI: 10.1038/nm.4268