Publications Peer reviewed articles (26) HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1. Author(s): Schoofs T, Klein F, Braunschweig M, Kreider EF, Feldmann A, Nogueira L, Oliveira T, Lorenzi JC, Parrish EH, Learn GH, West AP Jr, Bjorkman PJ, Schlesinger SJ, Seaman MS, Czartoski J, McElrath MJ, Pfeifer N, Hahn BH, Caskey M, Nussenzweig MC. Published in: Science, Issue May 20;352(6288):997-1001, 2016, ISSN 0036-8075 Publisher: American Association for the Advancement of Science DOI: 10.1126/science.aaf0972 Natively glycosylated HIV-1 Env structure reveals new mode for antibody recognition of the CD4-binding site Author(s): Gristick HB, von Boehmer L, West AP Jr, Schamber M, Gazumyan A, Golijanin J, Seaman MS, Fätkenheuer G, Klein F, Nussenzweig MC, Bjorkman PJ Published in: Nat Struct Mol Biol, Issue Oct;23(10):906-915, 2016, ISSN 1545-9993 Publisher: Nature Publishing Group DOI: 10.1038/nsmb.3291 Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV. Author(s): Theobald SJ, Kreer C, Khailaie S, Bonifacius A, Eiz-Vesper B, Figueiredo C, Mach M, Backovic M, Ballmaier M, Koenig J, Olbrich H, Schneider A, Volk V, Danisch S, Gieselmann L, Ercanoglu MS, Messerle M, Kaisenberg CV, Witte T, Klawonn F, Meyer-Hermann M, Klein F, Stripecke R. Published in: PLoS Pathog, Issue 16(7): e1008560, 2020, ISSN 1553-7374 Publisher: Pubic Library Science DOI: 10.1371/journal.ppat.1008560 Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizers Author(s): Vanshylla K, Fan C, Wunsch M, Poopalasingam N, Meijers M, Kreer C, Kleipass F, Ruchnewitz D, Ercanoglu MS, Gruell H, Münn F, Pohl K, Janicki H, Nolden T, Bartl S, Stein SC, Augustin M, Dewald F, Gieselmann L, Schommers P, Schulz TF, Sander LE, Koch M, Łuksza M, Lässig M, Bjorkman PJ, Klein F. Published in: Cell Host Microbe, Issue 30(1): 69-82.e10., 2022, ISSN 1931-3128 Publisher: Cell Press DOI: 10.1016/j.chom.2021.12.010 Evaluation of a New Spike (S)-Protein-Based Commercial Immunoassay for the Detection of Anti-SARS-CoV-2 IgG. Author(s): Eberhardt KA, Dewald F, Heger E, Gieselmann L, Vanshylla K, Wirtz M, Kleipass F, Johannis W, Schommers P, Gruell H, Brensing KA, Müller RU, Augustin M, Lehmann C, Koch M, Klein F, Di Cristanziano V. Published in: Microorganisms, Issue 31;9(4):733, 2021, ISSN 2076-2607 Publisher: MDPI DOI: 10.3390/microorganisms9040733 Relationship between intact HIV-1 proviruses in circulating CD4(+) T cells and rebound viruses emerging during treatment interruption Author(s): Lu CL, Pai JA, Nogueira L, Mendoza P, Gruell H, Oliveira TY, Barton J, Lorenzi JCC, Cohen YZ, Cohn LB, Klein F, Caskey M, Nussenzweig MC, Jankovic M. Published in: Acad Sci U S A, Issue 115(48): E11341-e8, 2018, ISSN 0027-8424 Publisher: National Academy of Sciences DOI: 10.1073/pnas.1813512115 Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV Author(s): Ehrhardt SA, Zehner M, Krahling V, Cohen-Dvashi H, Kreer C, Elad N, Gruell H, Ercanoglu MS, Schommers P, Gieselmann L, Eggeling R, Dahlke C, Wolf T, Pfeifer N, Addo MM, Diskin R, Becker S, Klein F. Published in: Nat Med, Issue 25(10):1589-1600., 2019, ISSN 1546-170X Publisher: Nature Publishing Group DOI: 10.1038/s41591-019-0602-4 Kinetics and correlates of the neutralizing antibody response to SARS-CoV-2 infection in humans. Author(s): Vanshylla K, Di Cristanziano V, Kleipass F, Dewald F, Schommers P, Gieselmann L, Gruell H, Schlotz M, Ercanoglu MS, Stumpf R, Mayer P, Zehner M, Heger E, Johannis W, Horn C, Suárez I, Jung N, Salomon S, Eberhardt KA, Gathof B, Fätkenheuer G, Pfeifer N, Eggeling R, Augustin M, Lehmann C, Klein F. Published in: Cell Host Microbe, Issue 29(6): 917-29.e4, 2021, ISSN 1931-3128 Publisher: Cell Press DOI: 10.1016/j.chom.2021.04.015 Antibody 10-1074 suppresses viremia in HIV-1-infected individuals Author(s): Caskey M, Schoofs T, Gruell H, Settler A, Karagounis T, Kreider EF, Murrell B, Pfeifer N, Nogueira L, Oliveira TY, Learn GH, Cohen YZ, Lehmann C, Gillor D, Shimeliovich I, Unson-O'Brien C, Weiland D, Robles A, Kümmerle T, Wyen C, Levin R, Witmer-Pack M, Eren K, Ignacio C, Kiss S, West AP, Jr., Mouquet H, Zingman BS, Gulick RM, Keler T, Bjorkman PJ, Seaman MS, Hahn BH, Fätkenheuer G, Schlesinger Published in: Nat Med, Issue 23(2): 185-91, 2017, ISSN 1078-8956 Publisher: Nature Publishing Group DOI: 10.1038/nm.4268 Broad and Potent Neutralizing Antibodies Recognize the Silent Face of the HIV Envelope Author(s): Schoofs T, Barnes CO, Suh-Toma N, Golijanin J, Schommers P, Gruell H, West AP, Jr., Bach F, Lee YE, Nogueira L, Georgiev IS, Bailer RT, Czartoski J, Mascola JR, Seaman MS, McElrath MJ, Doria-Rose NA, Klein F, Nussenzweig MC, Bjorkman PJ. Published in: Immunity, Issue 50(6): 1513-29 e9, 2019, ISSN 1074-7613 Publisher: Cell Press DOI: 10.1016/j.immuni.2019.04.014 Broadly neutralizing anti-HIV-1 monoclonal antibodies in the clinic Author(s): Caskey M, Klein F, Nussenzweig MC Published in: Nat Med, Issue 25(4): 547-53, 2019, ISSN 1078-8956 Publisher: Nature Publishing Group DOI: 10.1038/s41591-019-0412-8 Exploiting B Cell Receptor Analyses to Inform on HIV-1 Vaccination Strategies Author(s): Kreer C, Gruell H, Mora T, Walczak A.M. and Klein F. Published in: Vaccines, Issue 1;8(1):13, 2020, ISSN 2076-393X Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/vaccines8010013 Antibody-mediated prevention and treatment of HIV-1 infection. Author(s): Gruell H, Klein F. Published in: Retrovirology, Issue 15(1): 73, 2018, ISSN 1742-4690 Publisher: BioMed Central DOI: 10.1186/s12977-018-0455-9 Combination therapy with anti-HIV-1 antibodies maintains viral suppression Author(s): Pilar Mendoza, Henning Gruell, Lilian Nogueira, Joy A. Pai, Allison L. Butler, Katrina Millard, Clara Lehmann, Isabelle Suárez, Thiago Y. Oliveira, Julio C. C. Lorenzi, Yehuda Z. Cohen, Christoph Wyen, Tim Kümmerle, Theodora Karagounis, Ching-Lan Lu, Lisa Handl, Cecilia Unson-O’Brien, Roshni Patel, Carola Ruping, Maike Schlotz, Maggi Witmer-Pack, Irina Shimeliovich, Gisela Kremer, Eleonore Tho Published in: Nature, Issue 561/7724, 2018, Page(s) 479-484, ISSN 0028-0836 Publisher: Nature Publishing Group DOI: 10.1038/s41586-018-0531-2 Antibody-mediated prevention and treatment of HIV-1 infection Author(s): Henning Gruell, Florian Klein Published in: Retrovirology, Issue 15/1, 2018, ISSN 1742-4690 Publisher: BioMed Central DOI: 10.1186/s12977-018-0455-9 Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals Author(s): Yotam Bar-On, Henning Gruell, Till Schoofs, Joy A. Pai, Lilian Nogueira, Allison L. Butler, Katrina Millard, Clara Lehmann, Isabelle Suárez, Thiago Y. Oliveira, Theodora Karagounis, Yehuda Z. Cohen, Christoph Wyen, Stefan Scholten, Lisa Handl, Shiraz Belblidia, Juan P. Dizon, Jörg J. Vehreschild, Maggi Witmer-Pack, Irina Shimeliovich, Kanika Jain, Kerstin Fiddike, Kelly E. Seaton, Nicole L. Yate Published in: Nature Medicine, Issue 24/11, 2018, Page(s) 1701-1707, ISSN 1078-8956 Publisher: Nature Publishing Group DOI: 10.1038/s41591-018-0186-4 Broadly neutralizing anti-HIV-1 monoclonal antibodies in the clinic Author(s): Marina Caskey, Florian Klein, Michel C. Nussenzweig Published in: Nature Medicine, Issue 25/4, 2019, Page(s) 547-553, ISSN 1078-8956 Publisher: Nature Publishing Group DOI: 10.1038/s41591-019-0412-8 Relationship between intact HIV-1 proviruses in circulating CD4 + T cells and rebound viruses emerging during treatment interruption Author(s): Ching-Lan Lu, Joy A. Pai, Lilian Nogueira, Pilar Mendoza, Henning Gruell, Thiago Y. Oliveira, John Barton, Julio C. C. Lorenzi, Yehuda Z. Cohen, Lillian B. Cohn, Florian Klein, Marina Caskey, Michel C. Nussenzweig, Mila Jankovic Published in: Proceedings of the National Academy of Sciences, Issue 115/48, 2018, Page(s) E11341-E11348, ISSN 0027-8424 Publisher: National Academy of Sciences DOI: 10.1073/pnas.1813512115 HIV-1 therapy with monoclonal antibody 3BNC117 elicits host immune responses against HIV-1 Author(s): T. Schoofs, F. Klein, M. Braunschweig, E. F. Kreider, A. Feldmann, L. Nogueira, T. Oliveira, J. C. C. Lorenzi, E. H. Parrish, G. H. Learn, A. P. West, P. J. Bjorkman, S. J. Schlesinger, M. S. Seaman, J. Czartoski, M. J. McElrath, N. Pfeifer, B. H. Hahn, M. Caskey, M. C. Nussenzweig Published in: Science, Issue 352/6288, 2016, Page(s) 997-1001, ISSN 0036-8075 Publisher: American Association for the Advancement of Science DOI: 10.1126/science.aaf0972 Antibody 10-1074 suppresses viremia in HIV-1-infected individuals Author(s): Marina Caskey, Till Schoofs, Henning Gruell, Allison Settler, Theodora Karagounis, Edward F Kreider, Ben Murrell, Nico Pfeifer, Lilian Nogueira, Thiago Y Oliveira, Gerald H Learn, Yehuda Z Cohen, Clara Lehmann, Daniel Gillor, Irina Shimeliovich, Cecilia Unson-O'Brien, Daniela Weiland, Alexander Robles, Tim Kümmerle, Christoph Wyen, Rebeka Levin, Maggi Witmer-Pack, Kemal Eren, Caroline Ignacio, Sz Published in: Nature Medicine, Issue 23/2, 2017, Page(s) 185-191, ISSN 1078-8956 Publisher: Nature Publishing Group DOI: 10.1038/nm.4268 OpenPrimeR for multiplex amplification of highly diverse templates Author(s): Kreer C, Döring M, Lehnen N, Ercanoglu MS, Gieselmann L, Luca D, Jain K, Schommers P, Pfeifer N, Klein F. Published in: J Immunol Methods, Issue May;480:112752, 2020, ISSN 1872-7905 Publisher: Elsevier DOI: 10.1016/j.jim.2020.112752 Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody. Author(s): Schommers P, Gruell H, Abernathy ME, Tran M-K, Dingens AS, Gristick HB, Barnes CO, Schoofs T, Schlotz M, Vanshylla K, Kreer C, Weiland D, Holtick U, Scheid C, Valter MV, van Gils MJ, Sanders RW, Vehreschild JJ, Cornely OA, Lehmann C, Fätkenheuer G, Seaman MS, Bloom JD, Bjorkman J, Klein F. Published in: Cell, Issue Feb 6;180(3):471-489.e22, 2020, ISSN 1097-4172 Publisher: Cell press DOI: 10.1016/j.cell.2020.01.010 Effective high-throughput isolation of fully human antibodies targeting infectious pathogens Author(s): Gieselmann L, Kreer C, Ercanoglu MS, Lehnen N, Zehner M, Schommers P, Potthoff J, Gruell H, Klein F. Published in: Nat Protoc, Issue 16(7): 3639-71, 2021, ISSN 1754-2189 Publisher: Nature Publishing Group DOI: 10.1038/s41596-021-00554-w Safety and antiviral activity of combination HIV-1 broadly neutralizing antibodies in viremic individuals Author(s): Bar-On Y, Gruell H, Schoofs T, Pai JA, Nogueira L, Butler AL, Millard K, Lehmann C, Suárez I, Oliveira TY, Karagounis T, Cohen YZ, Wyen C, Scholten S, Handl L, Belblidia S, Dizon JP, Vehreschild JJ, Witmer-Pack M, Shimeliovich I, Jain K, Fiddike K, Seaton KE, Yates NL, Horowitz J, Gulick RM, Pfeifer N, Tomaras GD, Seaman MS, Fätkenheuer G, Caskey M, Klein F, Nussenzweig MC. Published in: Nat Med, Issue 24(11): 1701-7, 2018, ISSN 1078-8956 Publisher: Nature Publishing Group DOI: 10.1038/s41591-018-0186-4 Combination therapy with anti-HIV-1 antibodies maintains viral suppression Author(s): Mendoza P, Gruell H, Nogueira L, Pai JA, Butler AL, Millard K, Lehmann C, Suárez I, Oliveira TY, Lorenzi JCC, Cohen YZ, Wyen C, Kümmerle T, Karagounis T, Lu CL, Handl L, Unson-O'Brien C, Patel R, Ruping C, Schlotz M, Witmer-Pack M, Shimeliovich I, Kremer G, Thomas E, Seaton KE, Horowitz J, West AP, Jr., Bjorkman PJ, Tomaras GD, Gulick RM, Pfeifer N, Fätkenheuer G, Seaman MS, Klein F, Caskey M, Published in: Nature, Issue 561(7724): 479-84, 2018, ISSN 0028-0836 Publisher: Nature Publishing Group DOI: 10.1038/s41586-018-0531-2 CD34T+ Humanized Mouse Model to Study Mucosal HIV-1 Transmission and Prevention Author(s): Vanshylla K, Held K, Eser TM, Gruell H, Kleipass F, Stumpf R, Jain K, Weiland D, Münch J, Grüttner B, Geldmacher C, Klein F. . 2021; 9(3). Published in: Vaccines (Basel), Issue Feb 27;9(3):198, 2021, ISSN 2076-393X Publisher: Multidisciplinary Digital Publishing Institute (MDPI) DOI: 10.3390/vaccines9030198 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
