Objective
The beginning of this century has seen the development of optical super-resolution fluorescence microscopic methods, which yield pictures to resolutions of a few tens of nanometers. This breakthrough has transformed the field of cellular biology, but relies on approaches generally demanding in terms of optics, and which can be applied only on limited classes of fluorophores. This project aims at preparing the commercialization of a new, simple, and cheap, way of extracting super-resolution from images obtained with classical confocal fluorescence microscopes. Currently, this approach yields images with a resolution between 80 nm to 50 nm, which can most likely be increased in a near future. This method can thus be used with any type of fluorophore, just by equipping (confocal) microscopes with a high-end X-Y table and a 2D detector. More complex super-resolution fluorescence microscopic techniques have generated more than 7000 citations in the last years, mostly in biology, but also in chemistry and material sciences. The proposed technology, which can i) easily be implemented for a limited cost and ii) requires no more maintenance and alignment than classical confocal microscopy, is expected to be rapidly implemented in a very large number of laboratories, thus generating new knowledge and a vast range of scientific advances. In the frame of this project, which is a direct consequence of the work started in the frame of the PhotProt ERC advanced grant (id n° 267333), we will in parallel i) improve the performances of this technology by modifying its present design, ii) perform the necessary patenting of this technology, iii) start market studies to evaluate its actual commercial potential iv) enter in contact with companies devoted to microscope engineering and development, and with detector manufacturers, to raise their interest, and envision under which form this new technology can be commercialized, how to conceive the corresponding commercial prototype.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences physical sciences optics microscopy super resolution microscopy
- natural sciences physical sciences optics microscopy confocal microscopy
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
ERC-POC - Proof of Concept Grant
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2014-PoC
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1081 HV Amsterdam
Netherlands
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.