Deliverables
Directed random from Clostridium sp
Directed random from Clostridium sp
Improved epidemiology/ diagnostics
Role of sporulation genes determined
Target date for all starters
Given at nationalinternational meeting
Supervisory Board committee members selected
Prototype strain for clinical trial
Understanding sporulationtoxigenesis
Delivery of ethics documents before commencement of the relevant part of the research
Demonstrated in target Clostridium sp
Role of germination genes determined
Webdownloads and meeting flyers
Conference Proceedings at website
Subject to National requirements
Exemplified in target Clostridium
Conference Proceedings at website
Links to toxin/metabolite production
In pathogenic nonpathogenic clostridia
In C acetobutylicum Clostridium sp
Final Project report submitted to commission
Twitter account Facebook Page active
Website established at wwwclosporenet
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Publications
Author(s): Ioannis Mougiakos, Elleke F Bosma, Joyshree Ganguly, John van der Oost, Richard van Kranenburg
Published in: Current Opinion in Biotechnology, 50, 2018, Page(s) 146-157, ISSN 0958-1669
Publisher: Elsevier BV
DOI: 10.1016/j.copbio.2018.01.002
Author(s): Jeroen Girwar Koendjbiharie, Kilian Wiersma, Richard van Kranenburg
Published in: Applied and Environmental Microbiology, 84/13, 2018, Page(s) e00363-18, ISSN 0099-2240
Publisher: American Society for Microbiology
DOI: 10.1128/AEM.00363-18
Author(s): M. Diallo, A. D. Simons, H. van der Wal, F. Collas, Bwee Houweling-Tan, S. W. M. Kengen, A. M. López-Contreras
Published in: Applied and Environmental Microbiology, 2018, ISSN 0099-2240
Publisher: American Society for Microbiology
DOI: 10.1128/aem.02656-18
Author(s): Patrick Ingle, Daphne Groothuis, Peter Rowe, He Huang, Alan Cockayne, Sarah A. Kuehne, Weihong Jiang, Yang Gu, Christopher M. Humphreys, Nigel P. Minton
Published in: Scientific Reports, 9/1, 2019, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-44458-y
Author(s): Inés C. Cañadas, Daphne Groothuis, Maria Zygouropoulou, Raquel Rodrigues, Nigel P. Minton
Published in: ACS Synthetic Biology, 2019, ISSN 2161-5063
Publisher: American Chemical Society
DOI: 10.1021/acssynbio.9b00075