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Targeting Cartilage Regeneration in joint and intervertebral disc diseases

Deliverables

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Publications

Gold Nanocluster Extracellular Vesicle Supraparticles: Self-Assembled Nanostructures for Three-Dimensional Uptake Visualization.

Author(s): Kauscher U, Penders J, Nagelkerke A, Holme MN, Nele V, Massi L, Gopal S, Whittaker TE, Stevens MM. r
Published in: Langmui, 2020, ISSN 0743-7463
Publisher: American Chemical Society
DOI: 10.1021/acs.langmuir.9b03479

Enhanced chondrogenic phenotype of primary bovine articular chondrocytes in Fibrin-Hyaluronan hydrogel by multi-axial mechanical loading and FGF18.

Author(s): Antunes BP, Vainieri ML, Alini M, Monsonego-Ornan E, Grad S, Yayon A
Published in: Acta Biomaterialia, 2020, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2020.01.032

Tuneable peptide cross-linked nanogels for enzyme-triggered protein delivery

Author(s): Lucia Massi; Adrian Najer; Robert Chapman; Christopher D. Spicer; Valeria Nele; Junyi Che; Marsilea A. Booth; James Doutch; Molly M. Stevens
Published in: 2050-750X, 7, 2020, ISSN 2050-7518
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0tb01546f

Controlled Dendrimersome Nanoreactor System for Localized Hypochlorite-Induced Killing of Bacteria.

Author(s): Potter M, Najer A, Klöckner A, Zhang S, Holme MN, Nele V, Che J, Massi L, Penders J, Saunders C, Doutch JJ, Edwards AM, Ces O, Stevens MM
Published in: ACS Nano, 2021, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.0c07459

Hydrogel-based delivery of antimiR-221 enhances cartilage regeneration by endogenous cells

Author(s): Lolli, Andrea; Sivasubramaniyan, Kavitha; Vainieri, Maria Letizia; Oieni, J. (Jacopo); Kops, Nicole; Yayon, A. (A.); Osch, Gerjo
Published in: J Control Release, 3, 2019, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2019.07.040

Nano-ghosts: Novel biomimetic nano-vesicles for the delivery of antisense oligonucleotides.

Author(s): Oieni J, Lolli A, D'Atri D, Kops N, Yayon A, van Osch GJVM, Machluf M
Published in: J control release, 2021, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2021.03.018

Emerging potential of gene silencing approaches targeting anti-chondrogenic factors for cell-based cartilage repair.

Author(s): Andrea Lolli; Letizia Penolazzi; Roberto Narcisi; Gerjo J.V.M. van Osch; Roberta Piva
Published in: STARTPAGE=1;ENDPAGE=15;ISSN=1420682X;TITLE=Cellular and Molecular Life Sciences, 2, 2017, ISSN 1420-682X
Publisher: Birkhauser Verlag
DOI: 10.1007/s00018-017-2531-z

Functional cell phenotype induction with TGF-β1 and collagen-polyurethane scaffold for annulus fibrosus rupture repair.

Author(s): J. Du; Rose G. Long; Tomoko Nakai; Daisuke Sakai; Lorin Michael Benneker; G. Zhou; B. Li; David Eglin; James C. Iatridis; M. Alini; Sibylle Grad; Zhen Li
Published in: eur Cells Materials, 3, 2020, ISSN 1473-2262
Publisher: Swiss Society for Biomaterials
DOI: 10.22203/ecm.v039a01

Drug delivery in intervertebral disc degeneration and osteoarthritis: Selecting the optimal platform for the delivery of disease-modifying agents

Author(s): Colella F, Garcia JP, Sorbona M, Lolli A, Antunes B, D'Atri D, Barré FPY, Oieni J, Vainieri ML, Zerrillo L, Capar S, Häckel S, Cai Y, Creemers LB
Published in: J Control Release, 2020, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2020.08.041

Evaluation of biomimetic hyaluronic-based hydrogels with enhanced endogenous cell recruitment and cartilage matrix formation.

Author(s): Vainieri ML, Lolli A, Kops N, D'Atri D, Eglin D, Yayon A, Alini M, Grad S, Sivasubramaniyan K, van Osch GJVM
Published in: Acta Biomater, 2020, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2019.11.015

Modulation of Inflamed Synovium Improves Migration of Mesenchymal Stromal Cells in Vitro Through Anti-Inflammatory Macrophages.

Author(s): Wesdorp MA, Bastiaansen-Jenniskens YM, Capar S, Verhaar JAN, Narcisi R, Van Osch GJVM.
Published in: Cartilage, 2022, ISSN 1947-6035
Publisher: SAGE Publications Inc.
DOI: 10.1177/19476035221085136

Association between Oncostatin M Expression and Inflammatory Phenotype in Experimental Arthritis Models and Osteoarthritis Patients.

Author(s): J. Garcia; Lizette Utomo; Imke Rudnik-Jansen; Jie Du; Nicolaas P.A. Zuithoff; Anita Krouwels; Gerjo J.V.M. van Osch; Laura B. Creemers
Published in: Cells, 1, 2021, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells10030508

pH-responsive poly(lactide-co-glycolide) nanoparticles containing near-infrared dye for visualization and hyaluronic acid for treatment of osteoarthritis.

Author(s): Zerrillo, L.; Que, I.; Vepris, O.; Morgado, L.N.; Chan, A.; Bierau, K.; Li, Y.; Galli, F.; Bos, E.; Censi, R.; Di Martino, P.; van Osch, G.J.V.M.; Cruz, L.J.
Published in: VOLUME=309;STARTPAGE=265;ENDPAGE=276;TITLE=Journal of Controlled Release, 8, 2019, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2019.07.031

Fibrin-Hyaluronic Acid Hydrogel (RegenoGel) with Fibroblast Growth Factor-18 for In Vitro 3D Culture of Human and Bovine Nucleus Pulposus Cells.

Author(s): Häckel, Sonja; Zolfaghar, Mona; Du, Jie; Hoppe, Sven; Benneker, Lorin M.; Garstka, Nathalie; Peroglio, Marianna; Alini, Mauro; Grad, Sibylle; Yayon, Avner; Li, Zhen
Published in: International Journal of Molecular Sciences, Vol 20, Iss 20, p 5036 (2019), 1, 2019, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.7892/boris.134168

Regulation of Gdf5 expression in joint remodelling, repair and osteoarthritis

Author(s): Kania, Karolina; Colella, Fabio; Riemen, Anna H. K.; Wang, Hui; Howard, Kenneth A.; Aigner, Thomas; Dell’Accio, Francesco; Capellini, Terence D.; Roelofs, Anke J.; De Bari, Cosimo
Published in: Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020), 3, 2020, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-019-57011-8

Enhanced Sensitivity Using MALDI Imaging Coupled with Laser Postionization (MALDI-2) for Pharmaceutical Research.

Author(s): Barré, Florian P. Y.; Paine, Martin R. L.; Flinders, Bryn; Trevitt, Adam J.; Kelly, Patrick D.; Ait-Belkacem, Rima; Garcia, João P.; Creemers, Laura B.; Stauber, Jonathan; Vreeken, Rob J.; Cillero-Pastor, Berta; Ellis, Shane R.; Heeren, Ron M. A.
Published in: urn:issn:0003-2700, 1, 2019, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.9b02495

Molecular imaging of extracellular vesicles in vitro via Raman metabolic labelling

Author(s): Conor C. Horgan; Anika Nagelkerke; Thomas E. Whittaker; Valeria Nele; Lucia Massi; Ulrike Kauscher; Jelle Penders; Mads Sylvest Bergholt; Steve R. Hood; Molly M. Stevens
Published in: J mater chem B, 7, 2020, ISSN 2050-7518
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0tb00620c

Fatty Acid-Modified Gapmer Antisense Oligonucleotide and Serum Albumin Constructs for Pharmacokinetic Modulation

Author(s): Michael Lykke Hvam, Yunpeng Cai, Frederik Dagnæs-Hansen, Jesper Sejrup Nielsen, Jesper Wengel, Jørgen Kjems, Kenneth A. Howard
Published in: Molecular Therapy, 25/7, 2017, Page(s) 1710-1717, ISSN 1525-0016
Publisher: Nature Publishing Group
DOI: 10.1016/j.ymthe.2017.05.009

Specific Lipid and Metabolic Profiles of R-CHOP-Resistant Diffuse Large B-Cell Lymphoma Elucidated by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging and in Vivo Imaging

Author(s): Florian P.Y. Barré, Britt S.R. Claes, Frédéric Dewez, Carine Peutz-Kootstra, Helga F. Munch-Petersen, Kirsten Grønbæk, Anders H. Lund, Ron M.A. Heeren, Christophe Côme, Berta Cillero-Pastor
Published in: Analytical Chemistry, 90/24, 2018, Page(s) 14198-14206, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.8b02910

Fibrin-hyaluronic acid hydrogel-based delivery of antisense oligonucleotides for ADAMTS5 inhibition in co-delivered and resident joint cells in osteoarthritis

Author(s): João Pedro Garcia, Jeroen Stein, Yunpeng Cai, Frank Riemers, Ezequiel Wexselblatt, Jesper Wengel, Marianna Tryfonidou, Avner Yayon, Kenneth A. Howard, Laura B. Creemers
Published in: Journal of Controlled Release, 294, 2019, Page(s) 247-258, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2018.12.030

Targeting anti-chondrogenic factors for the stimulation of chondrogenesis: A new paradigm in cartilage repair

Author(s): Andrea Lolli, Fabio Colella, Cosimo De Bari, Gerjo J. V. M. van Osch
Published in: Journal of Orthopaedic Research®, 2018, ISSN 0736-0266
Publisher: Elsevier BV
DOI: 10.1002/jor.24136

Mechanically stimulated osteochondral organ culture for evaluation of biomaterials in cartilage repair studies

Author(s): M.L. Vainieri, D. Wahl, M. Alini, G.J.V.M. van Osch, S. Grad
Published in: Acta Biomaterialia, 81, 2018, Page(s) 256-266, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2018.09.058

Palmitoylated phosphodiester gapmer designs with albumin binding capacity and maintained in vitro gene silencing activity

Author(s): Yunpeng Cai, Anna-Marie Makarova, Jesper Wengel, Kenneth A. Howard
Published in: The Journal of Gene Medicine, 20/7-8, 2018, Page(s) e3025, ISSN 1099-498X
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/jgm.3025

Hyaluronan-based hydrogel delivering antimiR-221 for the guidance of endogenous cartilage repair

Author(s): A. Lolli, K. Sivasubramaniyan, M.L. Vainieri, D. Eglin, E. Wexselblatt, A. Yayon, S. Grad, M. Alini, G.J. van Osch
Published in: Osteoarthritis and Cartilage, 26, 2018, Page(s) S163, ISSN 1063-4584
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.joca.2018.02.355

Distribution, quantification and effects of triamcinolone acetonide in human osteoarthritic cartilage

Author(s): F.P. Barré, M. Paine, B. Flinders, M. Eveque-Mourroux, J. Garcia, S. Ellis, R.M. Heeren, L. Creemers, B. Cillero Pastor
Published in: Osteoarthritis and Cartilage, 26, 2018, Page(s) S284-S285, ISSN 1063-4584
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.joca.2018.02.574

Fibrin/hyaluronic acid hydrogel for combined delivery of gapmers and chondrocytes as a gene therapy approach for osteoarthritis

Author(s): J. Garcia, J. Stein, Y. Cai, E. Wexselblatt, L. Creemers, J. Wengel, K. Howard, D. Saris, A. Yayon
Published in: Osteoarthritis and Cartilage, 26, 2018, Page(s) S145, ISSN 1063-4584
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.joca.2018.02.313

YAP targeting in synovial MSCs as a novel therapeutic approach for osteoarthritis

Author(s): F. Colella, Y. Cai, K. Howard, A. Roelofs, C. De Bari
Published in: Osteoarthritis and Cartilage, 26, 2018, Page(s) S301, ISSN 1063-4584
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.joca.2018.02.605

Inhibiting Stat Signaling Pathways as a Possible Therapy to Modulate Synovial Inflammation in Osteoarthritis

Author(s): M.A. Suijkerbuijk, S. Çapar, N. Kops, D.E. Meuffels, G.J. van Osch, Y.M. Bastiaansen-Jenniskens
Published in: Osteoarthritis and Cartilage, 25, 2017, Page(s) S271-S272, ISSN 1063-4584
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.joca.2017.02.457

Depletion of the anti-chondrogenic regulators MIR-221 and slug: a novel approach to induce chondrogenesis

Author(s): A. Lolli, R. Narcisi, E. Lambertini, L. Penolazzi, M. Angelozzi, G.J. van Osch, R. Piva
Published in: Osteoarthritis and Cartilage, 24, 2016, Page(s) S39-S40, ISSN 1063-4584
Publisher: W. B. Saunders Co., Ltd.
DOI: 10.1016/j.joca.2016.01.095

The Paradoxical Effects of Chronic Intra-Amniotic <b><i>Ureaplasma parvum</i></b> Exposure on Ovine Fetal Brain Development

Author(s): Ruth Gussenhoven, Daan R.M.G. Ophelders, Matthew W. Kemp, Matthew S. Payne, Owen B. Spiller, Michael L. Beeton, Sarah J. Stock, Bertha Cillero-Pastor, Florian P.Y. Barré, Ron M.A. Heeren, Lilian Kessels, Bas Stevens, Bart P. Rutten, Suhas G. Kallapur, Alan H. Jobe, Boris W. Kramer, Tim G.A.M. Wolfs
Published in: Developmental Neuroscience, 39/6, 2017, Page(s) 472-486, ISSN 0378-5866
Publisher: S. Karger AG
DOI: 10.1159/000479021

Faster raster matrix-assisted laser desorption/ionization mass spectrometry imaging of lipids at high lateral resolution

Author(s): Florian Barré, Beatriz Rocha, Frédéric Dewez, Mark Towers, Paul Murray, Emmanuelle Claude, Berta Cillero-Pastor, Ron Heeren, Tiffany Porta Siegel
Published in: International Journal of Mass Spectrometry, 437, 2019, Page(s) 38-48, ISSN 1387-3806
Publisher: Elsevier BV
DOI: 10.1016/j.ijms.2018.09.015

Development and evaluation of matrix application techniques for high throughput mass spectrometry imaging of tissues in the clinic

Author(s): Lennart R.S. Huizing, Shane R. Ellis, Bart W.A.M.M. Beulen, Florian P.Y. Barré, Paul B. Kwant, Rob J. Vreeken, Ron M.A. Heeren
Published in: Clinical Mass Spectrometry, 12, 2019, Page(s) 7-15, ISSN 2376-9998
Publisher: elsevier
DOI: 10.1016/j.clinms.2019.01.004

Mass spectrometry imaging in nanomedicine: unravelling the potential of MSI for detection of nanoparticles in neuroscience

Author(s): Florian P.Y. Barré, Ron M. A. Heeren, Nina Ogrinc Potočnik
Published in: Current Pharmaceutical Design, 23, 2017, ISSN 1381-6128
Publisher: Bentham Science Publishers

A hyaluronic acid-based hydrogel enabling CD44-mediated chondrocyte binding and gapmer oligonucleotide release for modulation of gene expression in osteoarthritis

Author(s): Yunpeng Cai, Elena López-Ruiz, Jesper Wengel, Laura B. Creemers, Kenneth A. Howard
Published in: Journal of Controlled Release, 253, 2017, Page(s) 153-159, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2017.03.004

Derivatization Strategies for the Detection of Triamcinolone Acetonide in Cartilage by Using Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging

Author(s): Florian P. Y. Barré, Bryn Flinders, João P. Garcia, Imke Jansen, Lennart R. S. Huizing, Tiffany Porta, Laura B. Creemers, Ron M. A. Heeren, Berta Cillero-Pastor
Published in: Analytical Chemistry, 88/24, 2016, Page(s) 12051-12059, ISSN 0003-2700
Publisher: American Chemical Society
DOI: 10.1021/acs.analchem.6b02491

Emerging potential of gene silencing approaches targeting anti-chondrogenic factors for cell-based cartilage repair

Author(s): Andrea Lolli, Letizia Penolazzi, Roberto Narcisi, Gerjo J.V.M. van Osch, Roberta Piva
Published in: Cellular and Molecular Life Sciences, 2017, ISSN 1420-682X
Publisher: Birkhauser Verlag

Proinflammatory intervertebral disc cell and organ culture models induced by tumor necrosis factor alpha.

Author(s): Jie Du; Judith‐J. Pfannkuche; Gernot Lang; Sonja Häckel; Laura B. Creemers; Mauro Alini; Sibylle Grad; Zhen Li
Published in: JOR Spine, Vol 3, Iss 3, Pp n/a-n/a (2020), 2, 2020, ISSN 2572-1143
Publisher: Wiley
DOI: 10.48350/149054

Targeting the IL-6-Yap-Snail signalling axis in synovial fibroblasts ameliorates inflammatory arthritis.

Author(s): Rebecca A Symons; Fabio Colella; Fraser L. Collins; Alexandra J Rafipay; Karolina Kania; Jessica J McClure; Nathan White; Iain Cunningham; Sadaf Ashraf; Elizabeth A. Hay; Kevin Mackenzie; Kenneth A. Howard; Anna H. K. Riemen; Antonio Manzo; Susan Clark; Anke J. Roelofs; Cosimo De Bari
Published in: Annals of the Rheumatic Diseases, 1, 2021, ISSN 0003-4967
Publisher: BMJ Publishing Group
DOI: 10.1136/annrheumdis-2021-220875

Novel Fluorinated Poly (Lactic-Co-Glycolic acid) (PLGA) and Polyethylene Glycol (PEG) Nanoparticles for Monitoring and Imaging in Osteoarthritis.

Author(s): Zerrillo L, Gupta KBSS, Lefeber FAWM, Da Silva CG, Galli F, Chan A, Veltien A, Dou W, Censi R, Di Martino P, Srinivas M, Cruz L
Published in: Pharmaceutics, 2021, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics13020235

Targeting anti-chondrogenic factors for the stimulation of chondrogenesis: A new paradigm in cartilage repair.

Author(s): Andrea Lolli; Fabio Colella; Cosimo De Bari; Gerjo J.V.M. van Osch
Published in: Journal of Orthopaedic Research: a journal for musculoskeletal investigation, 1, 2018, ISSN 1554-527X
Publisher: Wiley
DOI: 10.1002/jor.24136

Mechanical Stress Inhibits Early Stages of Endogenous Cell Migration: A Pilot Study in an Ex Vivo Osteochondral Model.

Author(s): Vainieri ML, Alini M, Yayon A, van Osch GJVM, Grad S
Published in: Polymers, 2020, ISSN 2073-4360
Publisher: MPDI
DOI: 10.3390/polym12081754

Intra-articular Administration of Triamcinolone Acetonide in a Murine Cartilage Defect Model Reduces Inflammation but Inhibits Endogenous Cartilage Repair

Author(s): Wesdorp MA, Capar S, Bastiaansen-Jenniskens YM, Kops N, Creemers LB, Verhaar JAN, Van Osch GJVM, Wei W
Published in: Am J Sports Med, 2022, ISSN 0363-5465
Publisher: SAGE Publications
DOI: 10.1177/03635465221083693

Contrast enhanced computed tomography for real-time quantification of glycosaminoglycans in cartilage tissue engineered constructs

Author(s): Garcia, João P.; Longoni, Alessia; Gawlitta, Debby; J.W.P. Rosenberg, Antoine; Grinstaff, Mark W.; Töyräs, Juha; Weinans, Harrie; Creemers, Laura B.; Pouran, Behdad
Published in: urn:issn:1742-7061, 1, 2019, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2019.09.014

Nanoghosts targeted delivery of RNA interference therapy for the treatment of Osteoarthritis

Author(s): Jacopo Oieni, Marcelle Machluf
Published in: 2017
Publisher: ecmconferences

Effects of FGF18 on OA human articular chondrocytes embedded in a novel FBG:HA hydrogel

Author(s): Bernardo Antunes1,2, João Pedro Garcia3, Efrat Monsonego-Ornan2, Laura Creemers3, Avner Yayon1
Published in: 2017
Publisher: ecmconferences

Nano-ghosts delivery system and Link-N peptide, enhanced anti-inflammatory activity: a new approaches for the treatment of osteoarthritis

Author(s): Domenico D'Atri, Marcelle Machluf
Published in: 2017
Publisher: ecmconferences

Establishment of a hydrogel-based antimiR-221 delivery system for in situ guidance of cartilage repair

Author(s): Andrea Lolli1, Kavitha Sivasubramaniyan1, Gerjo van Osch1,2
Published in: 2017
Publisher: ecmconferences

Inhibiting STAT signaling pathways in macrophages to improve tissue regeneration

Author(s): Mathijs Suijkerbuijk, Serdar Çapar, Nicole Kops, Duncan Meuffels, Gerjo van Osch, Yvonne Bastiaansen-Jenniskens
Published in: 2017
Publisher: ecmconferences

Novel ex-vivo osteochondral model for cartilage repair in mechanical stimulated joint bioreactor

Author(s): ML Vainieri1,2, D Wahl 1, G Van Osch2, M Alini1, S Grad1
Published in: 2018, Page(s) 50
Publisher: ecmconferences

Novel ex-vivo osteochondral defect model in a joint bioreactor system for articular cartilage repair studies

Author(s): M.Letizia Vainieri, Dieter Whal, Patrick Leuzo, Gerjo van Osch, Mauro Alini, Sibylle Grad
Published in: 2017
Publisher: ecmconferences

3D non-invasive bioimaging of cartilage tissue engineered constructs using contrast enhanced computed tomography

Author(s): J.P. Garcia1, A. Longoni2, L.B. Creemers1, M.W. Grinstaff3, J. Töyräs4, H. Weinans1,5, B. Pouran1,5
Published in: 2018, Page(s) 44
Publisher: ecmconferences

A novel nano-ghosts based system for targeted delivery of antimir-221 and stimulation of cartilage repair

Author(s): J Oieni1, A Lolli2, GJVM van Osch2, M Machluf1
Published in: 2018, Page(s) 43
Publisher: ecmconferences

Effects of mechanical stimulation combined with FGF18 on bovine chondrocytes embedded in a novel Fibrin:HA hydrogel

Author(s): BP Antunes1, 2, ML Vainieri3, E Monsonego-Ornan2, M Alini3, S Grad3, A Yayon1
Published in: 2018, Page(s) 2
Publisher: ecmconferences

P268 - Antimir-221 Loaded Fibrin/Hyaluronic Acid Hydrogel For The Guidance Of Endogenous Cartilage Repair

Author(s): A. Lolli (Rotterdam, Netherlands), K. Sivasubramaniyan (Rotterdam, Netherlands), M. Vainieri (Davos Platz, Switzerland), A. Yayon (Nes Ziona, Israel), G. Van Osch (Rotterdam, Netherlands)
Published in: 2018
Publisher: ICRS

P75 - Hyaluronic acid-based hydrogels promote mesenchymal stem cell ingrowth and cartilage production in vitro and in vivo.

Author(s): M. Vainieri, K. Sivasubramaniyan, A. Lolli , D. Eglid , A. Yayon, E. Wexselblatt, M. Alini S. Grad , G. van Osch
Published in: 2018
Publisher: ICRS

Uniek onderzoek behandeling artroseL Slimme Medicijnen

Author(s): Gerben Stolk
Published in: Monitor, nummer 4, jaargang 46 (4x per year), 2017, Page(s) 34-35
Publisher: Erasmus MC

. Enzyme and temperature dual-responsive polymer nanostructures towards the treatment of osteoarthritis

Author(s): Massi L
Published in: 2019
Publisher: n.a.

Local and systemic delivery of gapmer antisense oligonucleotides for arthritis treatment

Author(s): Cai Y
Published in: 2018
Publisher: n.a.