Project description
International coordination in developing treatments for neurodegenerative diseases
The development of treatments that prevent or stop the progression of neurodegenerative diseases (ND) requires the highest level of coordination of national efforts to expedite discovery. The EU Joint Programme – Neurodegenerative Disease Research (JPND) involves 30 countries and has long-standing experience in collaborative actions regarding European and international research policies and joint project funding strategies. The EU-funded JPco-fuND project will support these collective efforts to focus on three priority areas: the identification of genetic, epigenetic and environmental risk factors, the development of longitudinal cohorts, and the creation of novel experimental models. These studies will increase understanding of ND mechanisms, resulting in significant acceleration of the execution of the JPND programme.
Objective
Over 12 million people in Europe suffer from neurodegenerative diseases (ND), yet treatments that prevent or stop the progression of neurodegeneration are still lacking. Tackling this grand challenge requires enhanced coordination of national efforts to accelerate discovery. Such synergies have been created among 28 countries in the pilot EU JPI on Neurodegenerative Disease Research (JPND). JPND has a long standing experience in collaborative action with €75 million of additional national funds being successfully mobilized between 2011 and 2014 to support transnational research programs. The JPND Research Strategy is now ripe for further enhancement in tight coordination with the EC through an ERA-Net Cofund instrument JPco-fuND with an unprecedented commitment of €30 million of national funds associated to a highly incentivizing EC top-up fund.
Among the most burning questions, three priority topics have emerged through a consultative process between researchers and JPND members in order to unlock several major issues within ND research: the identification of genetic, epigenetic and environmental risk and protective factors, the development and maintenance of longitudinal cohorts, the creation of advanced experimental models. These are key questions of equal priority to increase understanding of ND mechanisms that will be addressed through a common joint transnational call allowing a significant acceleration of the execution of the JPND research strategy. Moreover, to expand the impact of JPco-fuND, JPND will continue to implement other actions without EU co-funding such as aligning national research strategies, making databases more accessible and interoperable, developing enabling capacities such as supportive infrastructure and platforms, capacity building, education and training. These actions are required in parallel to achieve the highest impact for the patients, their carers and for society as whole and address this grand challenge in the coming years.
Fields of science
Programme(s)
Funding Scheme
ERA-NET-Cofund - ERA-NET CofundCoordinator
75654 Paris
France
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Participants (26)
75013 Paris
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Participation ended
1010 Wien
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00531 Helsinki
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101 38 Stockholm
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101 37 Stockholm
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K1T 4H8 Ottawa Ontario
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9101002 Jerusalem
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1100 Kobenhavn K
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51147 Koln
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0283 Oslo
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813 30 Bratislava
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2593 CE DEN HAAG
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SN2 1FL Swindon
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1249 074 Lisboa
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4365 Esch-Sur-Alzette
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1000 Bruxelles / Brussel
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1000 Bruxelles / Brussel
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00-801 WARSZAWA
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00144 Roma
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Participation ended
00153 Roma
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28029 Madrid
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06100 Ankara
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75013 Paris
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010168 Bucuresti
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1010 Wien
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00153 Roma
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