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CORDIS

Stem Cell therapy in IschEmic Non-treatable Cardiac diseasE (SCIENCE)

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

First patient treated (opens in new window)

First patient treated.

IMP production final (opens in new window)

Production of IMP for clinical trial final.

Clinical trial kick-off (opens in new window)

Clinical Trial Kick-off meeting with all clinical partners.

International workshop (opens in new window)

Arrangements for an international scientific workshop on stem cell-based treatment of cardiac disease.

Monitoring of clinical sites (opens in new window)

Monitoring of clinical sites.

Status on posting of results (opens in new window)

Report on the status of the posting of results (to the study registry).

Training logs (opens in new window)

Training logs for personnel complete

Quantification of cardiac fibrosis (opens in new window)

A clinically applicable technique to determine and quantify cardiac fibrosis by MRI

Determination of local deformation parameters (opens in new window)

Easy to use protocol for 3D echocardiography to determine local deformation parameters. Use the local myocardial deformation to assess the local effects of cardiac regenerative therapy on local cardiac function

Comprehensive cost-PU effectiveness (opens in new window)

Comprehensive cost-PU effectiveness: Using country comparisons results and refinement of methods, a conclusive assessment of the economic effects of ASC therapy can be given.

Planning tool for cardiac cell therapy (opens in new window)

Validation of a novel treatment planning tool for cardiac cell therapy, that is based on real time image integration

IP management (opens in new window)

IP management final.

Dissemination (opens in new window)

Dissemination to relevant groups and meetings. Production technology published in peer reviewed journal. Clinical trial design published in peer reviewed journal.

Preliminary cost-effectiveness analysis (opens in new window)

First preliminary results of health economics: Standard cost-effectiveness analysis of ASC therapy for each country involved, analysis of country differences

All approvals package (opens in new window)

All approvals from national ethics committees and national competent authorities of all study sites recieved.

Method for a financial analysis (opens in new window)

Developed tools: A methodology for a financial analysis of innovative medical technology will be set up comprising a software tool to be used on the spot by the developers of the technologies

Qualification of production facility (opens in new window)

Documentation of proper classification for sterile GMP production.

Website (opens in new window)

Establishment of SCIENCE website for public and partner use.

Publications

Intracoronary autologous bone marrow cell transfer after acute myocardial infarction: abort and refocus (opens in new window)

Author(s): Jozef Bartunek, Wojtek Wojakowski
Published in: European Heart Journal, Issue 38/39, 2017, Page(s) 2944-2947, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehx300

Global position paper on cardiovascular regenerative medicine (opens in new window)

Author(s): Francisco Fernández-Avilés, Ricardo Sanz-Ruiz, Andreu M. Climent, Lina Badimon, Roberto Bolli, Dominique Charron, Valentin Fuster, Stefan Janssens, Jens Kastrup, Hyo-Soo Kim, Thomas F. Lüscher, John F. Martin, Philippe Menasché, Robert D. Simari, Gregg W. Stone, Andre Terzic, James T. Willerson, Joseph C. Wu, Francisco Fernández-Avilés, Andre Terzic, Lina Badimon, Kathleen Broughton, Darcy L
Published in: European Heart Journal, Issue 38/33, 2017, Page(s) 2532-2546, ISSN 0195-668X
Publisher: Oxford University Press
DOI: 10.1093/eurheartj/ehx248

Rationale and design of the European multicentre study on Stem Cell therapy in IschEmic Non-treatable Cardiac diseasE (SCIENCE) (opens in new window)

Author(s): Christina Paitazoglou, Martin W. Bergmann, Bojan Vrtovec, Steven A.J. Chamuleau, Bas van Klarenbosch, Wojtek Wojakowski, Aleksandra Michalewska-Włudarczyk, Mariann Gyöngyösi, Annette Ekblond, Mandana Haack-Sørensen, Kai Jaquet, Karsten Vrangbaek, Jens Kastrup
Published in: European Journal of Heart Failure, 2019, ISSN 1388-9842
Publisher: Elsevier BV
DOI: 10.1002/ejhf.1412

Global Overview of the Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes (TACTICS) Recommendations (opens in new window)

Author(s): Francisco Fernández-Avilés, Ricardo Sanz-Ruiz, Andreu M. Climent, Lina Badimon, Roberto Bolli, Dominique Charron, Valentin Fuster, Stefan Janssens, Jens Kastrup, Hyo-Soo Kim, Thomas F. Lüscher, John F. Martin, Philippe Menasché, Fausto J. Pinto, Robert D. Simari, Gregg W. Stone, Andre Terzic, James T. Willerson, Joseph C. Wu
Published in: Circulation Research, Issue 122/2, 2018, Page(s) 199-201, ISSN 0009-7330
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/circresaha.117.312099

Intellectual Property Rights

STEM CELL THERAPY BASED ON ADIPOSE-DERIVED STEM CELLS

Application/Publication number: 20 16075407
Date: 2016-10-21
Applicant(s): REGION HOVEDSTADEN

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