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Stem Cell therapy in IschEmic Non-treatable Cardiac diseasE (SCIENCE)

Objective

Stem Cell therapy in IschEmic Non-treatable Cardiac diseasE (SCIENCE)

With more than 17 million deaths worldwide each year, ischemic heart disease (IHD) caused by coronary artery disease is the most common cause of death and a major cause of hospital admissions in industrialised countries. IHD caused over four million deaths in Europe in the year 2012 constituting 47% of all deaths. Today IHD is the main cause of death among women throughout Europe and the main cause of death among men in all but six European countries.

Conventional therapies have reduced mortality of IHD significantly, but have left an increasing number of patients with chronic IHD and/or heart failure without further treatment options. An increasing morbidity rate of this nature in an ageing population is a huge burden for society.

The overall aim of the SCIENCE project is to implement an effective stem cell-based therapy with allogeneic adipose derived stromal cells to improve myocardial function in patients with ischemic heart disease and heart failure. This goal will be achieved by conducting a multicentre clinical trial in a strong consortium of experienced international scientists and experts as well as significant representatives of the biomedical industry within translational medicine and a close collaboration with relevant authorities.

The consortium will ensure feasibility of treatment by simplifying and rationalising cell production and distribution using state-of-the art manufacturing technology that makes cell therapy a realistic option for clinical practise. The consortium expects the SCIENCE project to pave the way for future approval of this treatment by national authorities throughout Europe as the standard form of care for patients with ischemic heart disease and heart failure.

This concept will establish a new platform for growth and consolidation of innovative small and medium-size companies within stem cell research and development. Such a platform will ease implementati

Call for proposal

H2020-PHC-2014-2015

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Sub call

H2020-PHC-2014-single-stage

Coordinator

REGION HOVEDSTADEN
Net EU contribution
€ 3 309 862,00
Address
Kongens Vaenge 2
3400 Hillerod
Denmark

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Region
Danmark Hovedstaden Nordsjælland
Activity type
Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
Non-EU contribution
€ 0,00

Participants (9)

SLASKI UNIWERSYTET MEDYCZNY W KATOWICACH
Poland
Net EU contribution
€ 376 000,00
Address
Ul. Poniatowskiego 15
40 055 Katowice

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Region
Makroregion południowy Śląskie Katowicki
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

GORNOSLASKIE CENTRUM MEDYCZNE IM. PROF. LESZKA GIECA SLASKIEGO UNIWERSYTETU MEDYCZNEGO W KATOWICACH
Poland
Net EU contribution
€ 40 000,00
Address
Ul Ziolowa 45-47
40 635 Katowice

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Region
Makroregion południowy Śląskie Katowicki
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
MEDIZINISCHE UNIVERSITAET WIEN
Austria
Net EU contribution
€ 321 875,00
Address
Spitalgasse 23
1090 Wien

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Region
Wien Wien
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERZITETNI KLINICNI CENTER LJUBLJANA
Slovenia
Net EU contribution
€ 423 125,00
Address
Zaloska Cesta 002
1000 Ljubljana

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Region
Slovenija Zahodna Slovenija Osrednjeslovenska
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
TERUMO BCT EUROPE NV
Belgium
Net EU contribution
€ 232 083,00
Address
Ikaroslaan 41
1930 Zaventem

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Region
Vlaams Gewest Prov. Vlaams-Brabant Arr. Halle-Vilvoorde
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
UNIVERSITAIR MEDISCH CENTRUM UTRECHT
Netherlands
Net EU contribution
€ 670 625,00
Address
Heidelberglaan 100
3584 CX Utrecht

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Region
West-Nederland Utrecht Utrecht
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
WILLIAM COOK EUROPE APS
Denmark
Net EU contribution
€ 57 812,00
Address
Sandet 6
4632 Bjaeverskov

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Region
Danmark Sjælland Østsjælland
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
CARDIOLOGICUM HAMBURG
Germany
Net EU contribution
€ 423 750,00
Address
Schlossgarten 3
22041 Hamburg

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Region
Hamburg Hamburg Hamburg
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
KOBENHAVNS UNIVERSITET
Denmark
Net EU contribution
€ 143 750,00
Address
Norregade 10
1165 Kobenhavn

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Region
Danmark Hovedstaden Byen København
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00