Self-amplified photonic biosensing platform for microRNA-based early diagnosis of diseases

Project Information

SAPHELY

Grant agreement ID: 644242

DOI 10.3030/644242

Project closed

EC signature date 15 December 2014

Start date 1 February 2015

End date 31 July 2018

Funded under

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Information and Communication Technologies (ICT)

Total cost € 3 228 838,00

EU contribution € 3 228 838,00

Coordinated by

UNIVERSITAT POLITECNICA DE VALENCIA
Spain

Deliverables

Documents, reports (5)

Final roadmap for future POC IVC devices

First version of the roadmap for future POC IVD devices

Final report on the project's societal impact and implication

Composition of the end-users advisory panel

Report on combination to standardization of the SAPHELY project

Websites, patent fillings, videos etc. (6)

Updated version of the Data Management Plan

SAPHELY promotional material

Creation of a final SAPHELY Dissemination Kit

SAPHELY project website set up

First draft of the Data Management Plan

Final report on dissemination and promotion of project results

Open Research Data Pilot (1)

Final version of the Data Management Plan

Publications

Peer reviewed articles (5)

Lysozyme Photochemistry as a Function of Temperature. The Protective Effect of Nanoparticles on Lysozyme Photostability

Author(s): Catarina Oliveira Silva, Steffen B. Petersen, Catarina Pinto Reis, Patrícia Rijo, Jesús Molpeceres, Henrik Vorum, Maria Teresa Neves-Petersen
Published in: PLOS ONE, Issue 10/12, 2015, Page(s) e0144454, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0144454

Experimental study of the evanescent-wave photonic sensors response in presence of molecular beacon conformational changes

Author(s): Ángela Ruiz-Tórtola, Francisco Prats-Quílez, Daniel González-Lucas, María-José Bañuls, Ángel Maquieira, Guy Wheeler, Tamas Dalmay, Amadeu Griol, Juan Hurtado, Helge Bohlmann, Reiner Götzen, Jaime García-Rupérez
Published in: Journal of Biophotonics, 2018, Page(s) e201800030, ISSN 1864-063X
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/jbio.201800030

Covalent attachment of biotinylated molecular beacons via thiol-ene coupling. A study on conformational changes upon hybridization and streptavidin binding

Author(s): Daniel González-Lucas, María-José Bañuls, Jaime García-Rupérez, Ángel Maquieira
Published in: Microchimica Acta, Issue 184/9, 2017, Page(s) 3231-3238, ISSN 0026-3672
Publisher: Springer Verlag
DOI: 10.1007/s00604-017-2310-4

High sensitivity and label-free oligonucleotides detection using photonic bandgap sensing structures biofunctionalized with molecular beacon probes

Author(s): Ángela Ruiz-Tórtola, Francisco Prats-Quílez, Daniel González-Lucas, María-José Bañuls, Ángel Maquieira, Guy Wheeler, Tamas Dalmay, Amadeu Griol, Juan Hurtado, Jaime García-Rupérez
Published in: Biomedical Optics Express, Issue 9/4, 2018, Page(s) 1717, ISSN 2156-7085
Publisher: The Optical Society
DOI: 10.1364/BOE.9.001717

Improved Performance of DNA Microarray Multiplex Hybridization Using Probes Anchored at Several Points by Thiol–Ene or Thiol–Yne Coupling Chemistry

Author(s): Maria-Jose Bañuls, Pilar Jiménez-Meneses, Albert Meyer, Jean-Jacques Vasseur, François Morvan, Jorge Escorihuela, Rosa Puchades, Ángel Maquieira
Published in: Bioconjugate Chemistry, Issue 28/2, 2017, Page(s) 496-506, ISSN 1043-1802
Publisher: American Chemical Society
DOI: 10.1021/acs.bioconjchem.6b00624

Intellectual Property Rights

Patent (2)

DISPOSITIVO Y MÉTODO DE SENSADO FOTÓNICO QUE COMPRENDEN ELEMENTOS DE BIORECONOCIMIENTO CON CAMBIO CONFORMACIONAL

Application/Publication number: ES P201631409
Date: 2016-11-04

DISPOSITIVO Y MÉTODO DE SENSADO FOTÓNICO QUE COMPRENDEN ELEMENTOS DE BIORECONOCIMIENTO CON CAMBIO CONFORMACIONAL

Application/Publication number: ES P201631409
Date: 2016-11-04