Objective
The aim of this project is to bring together subject matter experts from the academic and non-academic sectors to develop a platform of “green” chemoenzymatic methods for the production of high value active pharmaceutical ingredients – both those currently on the market, and those in development pipelines of the Pharma industry. The partners will exemplify the use of the platform through its application in the production of 4 drugs currently on the market – namely Duloxetine, Atomexetine, Ramosetron and Paricalcitol.
In order to achieve this objective the proposal brings together 3 partners with complementary skills:
Kelada Pharmachem: Phase transfer catalysis/organo catalysis/scale-up of chemical processes
Cerbios Pharma: Biocatalysis and fermentation methodologies for drug production
IC-CNR: Protein crystallography and enzymatic engineering
Fields of science
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugs
- natural scienceschemical sciencesorganic chemistryketones
- natural sciencesearth and related environmental sciencesgeologymineralogycrystallography
- natural scienceschemical sciencesorganic chemistryalcohols
- engineering and technologyindustrial biotechnologybioprocessing technologiesfermentation
Call for proposal
H2020-MSCA-RISE-2014
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Coordinator
00185 Roma
Italy
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Participants (1)
A94 Dublin
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Partners (1)
6917 Barbengo
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