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Chemo-Enzymatic Manufacturing Routes to High- Value compounds

Objective

The aim of this project is to bring together subject matter experts from the academic and non-academic sectors to develop a platform of “green” chemoenzymatic methods for the production of high value active pharmaceutical ingredients – both those currently on the market, and those in development pipelines of the Pharma industry. The partners will exemplify the use of the platform through its application in the production of 4 drugs currently on the market – namely Duloxetine, Atomexetine, Ramosetron and Paricalcitol.
In order to achieve this objective the proposal brings together 3 partners with complementary skills:
Kelada Pharmachem: Phase transfer catalysis/organo catalysis/scale-up of chemical processes
Cerbios Pharma: Biocatalysis and fermentation methodologies for drug production
IC-CNR: Protein crystallography and enzymatic engineering

Coordinator

CONSIGLIO NAZIONALE DELLE RICERCHE
Net EU contribution
€ 162 000,00
Address
Piazzale Aldo Moro 7
00185 Roma
Italy

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Region
Centro (IT) Lazio Roma
Activity type
Research Organisations
Other funding
€ 0,00

Participants (1)

KELADA PHARMACHEM LIMITED
Ireland
Net EU contribution
€ 72 000,00
Address
161 Rathmines Road Lower
A94 Dublin

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ireland Eastern and Midland Dublin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00

Partners (1)

Partner

Partner organisations contribute to the implementation of the action, but do not sign the Grant Agreement.

CERBIOS-PHARMA SA
Switzerland
Net EU contribution
€ 0,00
Address
Via Figinio 6
6917 Barbengo

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Schweiz/Suisse/Svizzera Ticino Ticino
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00