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Chemo-Enzymatic Manufacturing Routes to High- Value compounds

Objective

The aim of this project is to bring together subject matter experts from the academic and non-academic sectors to develop a platform of “green” chemoenzymatic methods for the production of high value active pharmaceutical ingredients – both those currently on the market, and those in development pipelines of the Pharma industry. The partners will exemplify the use of the platform through its application in the production of 4 drugs currently on the market – namely Duloxetine, Atomexetine, Ramosetron and Paricalcitol.
In order to achieve this objective the proposal brings together 3 partners with complementary skills:
Kelada Pharmachem: Phase transfer catalysis/organo catalysis/scale-up of chemical processes
Cerbios Pharma: Biocatalysis and fermentation methodologies for drug production
IC-CNR: Protein crystallography and enzymatic engineering

Field of science

  • /social sciences/economics and business/business and management/commerce
  • /engineering and technology/industrial biotechnology/bioprocessing technologies/biocatalysis
  • /natural sciences/earth and related environmental sciences/geology/mineralogy/crystallography
  • /engineering and technology/industrial biotechnology/bioprocessing technologies/fermentation

Call for proposal

H2020-MSCA-RISE-2014
See other projects for this call

Funding Scheme

MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)

Coordinator

CONSIGLIO NAZIONALE DELLE RICERCHE
Address
Piazzale Aldo Moro 7
00185 Roma
Italy
Activity type
Research Organisations
EU contribution
€ 162 000

Participants (1)

KELADA PHARMACHEM LIMITED
Ireland
EU contribution
€ 72 000
Address
21 Obelisk Rise
A94 Dublin
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)

Partners (1)

CERBIOS-PHARMA SA
Switzerland
Address
Via Figinio 6
6917 Barbengo
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)