Obiettivo
The aim of this project is to bring together subject matter experts from the academic and non-academic sectors to develop a platform of “green” chemoenzymatic methods for the production of high value active pharmaceutical ingredients – both those currently on the market, and those in development pipelines of the Pharma industry. The partners will exemplify the use of the platform through its application in the production of 4 drugs currently on the market – namely Duloxetine, Atomexetine, Ramosetron and Paricalcitol.
In order to achieve this objective the proposal brings together 3 partners with complementary skills:
Kelada Pharmachem: Phase transfer catalysis/organo catalysis/scale-up of chemical processes
Cerbios Pharma: Biocatalysis and fermentation methodologies for drug production
IC-CNR: Protein crystallography and enzymatic engineering
Campo scientifico
- medical and health sciencesbasic medicinepharmacology and pharmacypharmaceutical drugs
- natural scienceschemical sciencesorganic chemistryketones
- natural sciencesearth and related environmental sciencesgeologymineralogycrystallography
- natural scienceschemical sciencesorganic chemistryalcohols
- engineering and technologyindustrial biotechnologybioprocessing technologiesfermentation
Programma(i)
Meccanismo di finanziamento
MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)Coordinatore
00185 Roma
Italia