Muscle Stress Relief: An integrated research program linking together basic research on secondary myopathies in stress states to innovative translation in applied myology.

Información del proyecto

Muscle stress relief

Identificador del acuerdo de subvención: 645648

DOI

10.3030/645648

Proyecto cerrado

Fecha de la firma de la CE 3 Diciembre 2014

Fecha de inicio 1 Marzo 2016

Fecha de finalización 29 Febrero 2020

Financiado con arreglo a

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Coste total

€ 1 606 500,00

Aportación de la UE

€ 1 458 000,00

Coordinado por

PANEPISTIMIO THESSALIAS
Greece

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

Websites, patent fillings, videos etc. (1)

Management

D7.1 Establish the Muscle Stress Relief network office and the project's website

Other (1)

Workshop

D 7.3: Workshop in Athens (as above, as a Satellite event) and biannual ESR retreat

Publicaciones

Peer reviewed articles (24)

Age-Associated Loss of OPA1 in Muscle Impacts Muscle Mass, Metabolic Homeostasis, Systemic Inflammation, and Epithelial Senescence

Autores: Caterina Tezze, Vanina Romanello, Maria Andrea Desbats, Gian Paolo Fadini, Mattia Albiero, Giulia Favaro, Stefano Ciciliot, Maria Eugenia Soriano, Valeria Morbidoni, Cristina Cerqua, Stefan Loefler, Helmut Kern, Claudio Franceschi, Stefano Salvioli, Maria Conte, Bert Blaauw, Sandra Zampieri, Leonardo Salviati, Luca Scorrano, Marco Sandri
Publicado en: Cell Metabolism, Edición 25/6, 2017, Página(s) 1374-1389.e6, ISSN 1550-4131
Editor: Cell Press
DOI: 10.1016/j.cmet.2017.04.021

Modulators of actin-myosin dissociation: basis for muscle type functional differences during fatigue

Autores: Christina Karatzaferi, Nancy Adamek, Michael A Geeves
Publicado en: American Journal of Physiology - Cell Physiology, 2017, Página(s) ajpcell.00023.2017, ISSN 0363-6143
Editor: American Physiological Society
DOI: 10.1152/ajpcell.00023.2017

Immunostick ELISA for rapid and easy diagnosis of myasthenia gravis

Autores: Nikolaos Trakas, Socrates J. Tzartos
Publicado en: Journal of Immunological Methods, Edición 460, 2018, Página(s) 107-112, ISSN 0022-1759
Editor: Elsevier BV
DOI: 10.1016/j.jim.2018.06.016

Positive End-Expiratory Pressure Ventilation Induces Longitudinal Atrophy in Diaphragm Fibers

Autores: Johan Lindqvist, Marloes van den Berg, Robbert van der Pijl, Pleuni E. Hooijman, Albertus Beishuizen, Judith Elshof, Monique de Waard, Armand Girbes, Angelique Spoelstra-de Man, Zhong-Hua Shi, Charissa van den Brom, Sylvia Bogaards, Shengyi Shen, Joshua Strom, Henk Granzier, Jeroen Kole, René J. P. Musters, Marinus A. Paul, Leo M. A. Heunks, Coen A. C. Ottenheijm
Publicado en: American Journal of Respiratory and Critical Care Medicine, Edición 198/4, 2018, Página(s) 472-485, ISSN 1073-449X
Editor: American Thoracic Society
DOI: 10.1164/rccm.201709-1917OC

Functional responses of uremic single skeletal muscle fibers to redox imbalances

Autores: Mitrou GI, Poulianiti KP, Koutedakis Y, Jamurtas AZ, Maridaki MD, Stefanidis I, Sakkas GK, Karatzaferi C
Publicado en: Hippokratia, Edición 21(1), 2017, Página(s) 3-7, ISSN 1108-4189
Editor: Lithografia Antoniadis I - Psarras Th G.P

Evidence of Blood and Muscle Redox Status Imbalance in Experimentally Induced Renal Insufficiency in a Rabbit Model

Autores: Konstantina P. Poulianiti, Aggeliki Karioti, Antonia Kaltsatou, Georgia I. Mitrou, Yiannis Koutedakis, Konstantinos Tepetes, Grigoris Christodoulidis, Giannis Giakas, Maria D. Maridaki, Ioannis Stefanidis, Athanasios Z. Jamurtas, Giorgos K. Sakkas, Christina Karatzaferi
Publicado en: Oxidative Medicine and Cellular Longevity, Edición 2019, 2019, Página(s) 1-14, ISSN 1942-0900
Editor: Landes Bioscience
DOI: 10.1155/2019/8219283

Evidence of functional deficits at the single muscle fiber level in experimentally-induced renal insufficiency

Autores: Georgia I. Mitrou, Giorgos K. Sakkas, Konstantina P. Poulianiti, Aggeliki Karioti, Konstantinos Tepetes, Grigorios Christodoulidis, Giannis Giakas, Ioannis Stefanidis, Michael A. Geeves, Yiannis Koutedakis, Christina Karatzaferi
Publicado en: Journal of Biomechanics, Edición 82, 2019, Página(s) 259-265, ISSN 0021-9290
Editor: Elsevier BV
DOI: 10.1016/j.jbiomech.2018.10.035

MuRF1 and MuRF2 are key players in skeletal muscle regeneration involving myogenic deficit and deregulation of the chromatin-remodeling complex

Autores: Anselmo Sigari Moriscot, Igor Luchini Baptista, William José Silva, João Guilherme Silvestre, Volker Adams, Alexander Gasch, Julius Bogomolovas, Siegfried Labeit
Publicado en: JCSM Rapid Communications, Edición 2/1, 2019, Página(s) 1-25, ISSN 2617-1619
Editor: Wiley Online Library
DOI: 10.1002/j.2617-1619.2019.tb00010.x

miR‐29c improves skeletal muscle mass and function throughout myocyte proliferation and differentiation and by repressing atrophy‐related genes

Autores: William José Silva, Flavia Aparecida Graça, André Cruz, João Guilherme Silvestre, Siegfried Labeit, Elen Haruka Miyabara, Chao Yun Irene Yan, Da Zhi Wang, Anselmo Sigari Moriscot
Publicado en: Acta Physiologica, 2019, Página(s) e13278, ISSN 1748-1708
Editor: Blackwell Publishing Inc.
DOI: 10.1111/apha.13278

Diaphragm contractile weakness due to reduced mechanical loading: role of titin

Autores: Robbert J. van der Pijl, Henk L. Granzier, Coen A. C. Ottenheijm
Publicado en: American Journal of Physiology-Cell Physiology, Edición 317/2, 2019, Página(s) C167-C176, ISSN 0363-6143
Editor: American Physiological Society
DOI: 10.1152/ajpcell.00509.2018

Titin-based mechanosensing modulates muscle hypertrophy

Autores: Robbert van der Pijl, Joshua Strom, Stefan Conijn, Johan Lindqvist, Siegfried Labeit, Henk Granzier, Coen Ottenheijm
Publicado en: Journal of Cachexia, Sarcopenia and Muscle, Edición 9/5, 2018, Página(s) 947-961, ISSN 2190-5991
Editor: Springer Verlag
DOI: 10.1002/jcsm.12319

The E3 ligase MuRF2 plays a key role in the functional capacity of skeletal muscle fibroblasts

Autores: J.G. Silvestre, I.L. Baptista, W.J. Silva, A. Cruz, M.T. Silva, E.H. Miyabara, S. Labeit, A.S. Moriscot
Publicado en: Brazilian Journal of Medical and Biological Research, Edición 52/9, 2019, ISSN 0100-879X
Editor: Associacao Brasileira de Divulgacao Cientifica
DOI: 10.1590/1414-431x20198551

Deciphering anti-MOG IgG antibodies: Clinical and radiological spectrum, and comparison of antibody detection assays

Autores: John S. Tzartos, Katerina Karagiorgou, Dimitrios Tzanetakos, Marianthi Breza, Maria Eleftheria Evangelopoulos, Sygkliti-Henrietta Pelidou, Christos Bakirtzis, Ioannis Nikolaidis, Georgios Koutsis, Konstantinos Notas, Elisabeth Chroni, Ioannis Markakis, Nikolaos C. Grigoriadis, Maria Anagnostouli, Anastasios Orologas, Dimitrios Parisis, Theodoros Karapanayiotides, Dimitra Papadimitriou, Vasiliki Ko
Publicado en: Journal of the Neurological Sciences, Edición 410, 2020, Página(s) 116673, ISSN 0022-510X
Editor: Elsevier BV
DOI: 10.1016/j.jns.2020.116673

DRP1-mediated mitochondrial shape controls calcium homeostasis and muscle mass

Autores: Giulia Favaro, Vanina Romanello, Tatiana Varanita, Maria Andrea Desbats, Valeria Morbidoni, Caterina Tezze, Mattia Albiero, Marta Canato, Gaia Gherardi, Diego De Stefani, Cristina Mammucari, Bert Blaauw, Simona Boncompagni, Feliciano Protasi, Carlo Reggiani, Luca Scorrano, Leonardo Salviati, Marco Sandri
Publicado en: Nature Communications, Edición 10/1, 2019, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-019-10226-9

Inhibition of the Fission Machinery Mitigates OPA1 Impairment in Adult Skeletal Muscles

Autores: Vanina Romanello, Marco Scalabrin, Mattia Albiero, Bert Blaauw, Luca Scorrano, Marco Sandri
Publicado en: Cells, Edición 8/6, 2019, Página(s) 597, ISSN 2073-4409
Editor: MDPI
DOI: 10.3390/cells8060597

Small‐molecule‐mediated chemical knock‐down of MuRF1/MuRF2 and attenuation of diaphragm dysfunction in chronic heart failure

Autores: Volker Adams, T. Scott Bowen, Sarah Werner, Peggy Barthel, Christina Amberger, Anne Konzer, Johannes Graumann, Peter Sehr, Joe Lewis, Jan Provaznik, Vladimir Benes, Petra Büttner, Alexander Gasch, Norman Mangner, Christian C. Witt, Dittmar Labeit, Axel Linke, Siegfried Labeit
Publicado en: Journal of Cachexia, Sarcopenia and Muscle, Edición 10/5, 2019, Página(s) 1102-1115, ISSN 2190-5991
Editor: Springer Verlag
DOI: 10.1002/jcsm.12448

Effects of Redox Disturbances on Motility, Contractility and Muscle Tissue Pathogenesis

Autores: C. Karatzaferi, M. Sandri, G. K. Sakkas, C. Smith
Publicado en: Oxidative Medicine and Cellular Longevity, Edición 2019, 2019, Página(s) 1-2, ISSN 1942-0900
Editor: Landes Bioscience
DOI: 10.1155/2019/3272035

Expression of MuRF1 or MuRF2 is essential for the induction of skeletal muscle atrophy and dysfunction in a murine pulmonary hypertension model

Autores: Thanh Nguyen, T. Scott Bowen, Antje Augstein, Antje Schauer, Alexander Gasch, Axel Linke, Siegfried Labeit, Volker Adams
Publicado en: Skeletal Muscle, Edición 10/1, 2020, ISSN 2044-5040
Editor: BioMed Central
DOI: 10.1186/s13395-020-00229-2

Cardiac specific titin N2B exon is a novel sensitive serological marker for cardiac injury

Autores: Julius Bogomolovas, Alexander Gasch, Vilhelmas Bajoras, Dovilė Karčiauskaitė, Pranas Šerpytis, Virginija Grabauskienė, Dittmar Labeit, Siegfried Labeit
Publicado en: International Journal of Cardiology, Edición 212, 2016, Página(s) 232-234, ISSN 0167-5273
Editor: Elsevier BV
DOI: 10.1016/j.ijcard.2016.03.045

Skeletal muscle atrophy: disease-induced mechanisms may mask disuse atrophy

Autores: C. J. Malavaki, G. K. Sakkas, G. I. Mitrou, A. Kalyva, I. Stefanidis, K. H. Myburgh, C. Karatzaferi
Publicado en: Journal of Muscle Research and Cell Motility, Edición 36/6, 2015, Página(s) 405-421, ISSN 0142-4319
Editor: Kluwer Academic Publishers
DOI: 10.1007/s10974-015-9439-8

Titin antibodies in “seronegative” myasthenia gravis — A new role for an old antigen

Autores: C. Stergiou, K. Lazaridis, V. Zouvelou, J. Tzartos, R. Mantegazza, C. Antozzi, F. Andreetta, A. Evoli, F. Deymeer, G. Saruhan-Direskeneli, H. Durmus, T. Brenner, A. Vaknin, S. Berrih-Aknin, A. Behin, T. Sharshar, M. De Baets, M. Losen, P. Martinez-Martinez, K.A. Kleopa, E. Zamba-Papanicolaou, T. Kyriakides, A. Kostera-Pruszczyk, P. Szczudlik, B. Szyluk, D. Lavrnic, I. Basta, S. Peric, C. Tallaksen
Publicado en: Journal of Neuroimmunology, Edición 292, 2016, Página(s) 108-115, ISSN 0165-5728
Editor: Elsevier BV
DOI: 10.1016/j.jneuroim.2016.01.018

The Binding Sites of miR-619-5p in the mRNAs of Human and Orthologous Genes

Autores: Shara Atambayeva, Raigul Niyazova, Anatoliy Ivashchenko, Anna Pyrkova, Ilya Pinsky, Aigul Akimniyazova, Siegfried Labeit
Publicado en: BMC Genomics, Edición 18/1, 2017, ISSN 1471-2164
Editor: BioMed Central
DOI: 10.1186/s12864-017-3811-6

Small-molecule inhibition of MuRF1 attenuates skeletal muscle atrophy and dysfunction in cardiac cachexia

Autores: Thomas Scott Bowen, Volker Adams, Sarah Werner, Tina Fischer, Paulien Vinke, Maria Noel Brogger, Norman Mangner, Axel Linke, Peter Sehr, Joe Lewis, Dittmar Labeit, Alexander Gasch, Siegfried Labeit
Publicado en: Journal of Cachexia, Sarcopenia and Muscle, 2017, ISSN 2190-5991
Editor: Springer Verlag
DOI: 10.1002/jcsm.12233

Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Improves Energetic Status and Cardiomyogenic Differentiation of Human Dilated Myocardium-Derived Primary Mesenchymal Cells

Autores: Rokas Miksiunas, Kestutis Rucinskas, Vilius Janusauskas, Siegfried Labeit, Daiva Bironaite
Publicado en: International Journal of Molecular Sciences, Edición 21/14, 2020, Página(s) 4845, ISSN 1422-0067
Editor: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21144845