Objective
The main objective of VIVOIMAG is to develop bone implants including a new contrast agent sensitive to enzymatic activity of metaloproteases, which will permit for the first time to follow the integration and cell differentiation activity in bone tissue bioreactors in vitro and in grafts in vivo using existing non invasive magnetic resonance imaging techniques. The proposal aims at integrating a magnetically functionalized extracellular matrix material into the bone scaffolds, seeding them with cells, implanting them in animal models and following the fate of the implants in vivo using MRI. The aim is to obtain similar results with the magnetically modified scaffolds as the ones obtained currently but having now endowed the grafts with enzymatic reporting activity that can be monitored noninvasively in the living animal. There are currently no methods to detect in situ and in vivo this enzymatic activity without previously sacrificing the transplanted animals, therefore the successful accomplishment of this project would have huge and prolonged impact in the medical field of tissue regeneration.
The VIVOIMAG project brings together a multidisciplinary consortium of specialists in different areas of bone implant research, nanoparticles formulation and characterization, magnetic resonance and scintigraphic imaging, who will join forces in order to propose and assess a novel technique for the evaluation of the progress of bone implants in vivo, which can substitute existing invasive techniques based on biopsies.
A well planned exchange program among academic and industrial partners will facilitate knowledge sharing, maximize collaborative work and finally achievement of project objectives. The consortium, being aware of the scientific and social importance of bone tissue engineering, has planned a series of dissemination and training activities, aiming at making project knowledge and outcomes available to the scientific community and society.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences clinical medicine surgery
- medical and health sciences medical biotechnology tissue engineering
- medical and health sciences medical biotechnology nanomedicine
- engineering and technology medical engineering diagnostic imaging magnetic resonance imaging
- medical and health sciences medical biotechnology implants artificial bone
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.3. - EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions
MAIN PROGRAMME
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H2020-EU.1.3.3. - Stimulating innovation by means of cross-fertilisation of knowledge
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-MSCA-RISE-2014
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
15 341 AGIA PARASKEVI
Greece
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.